{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T08:40:59Z","timestamp":1760517659138,"version":"build-2065373602"},"reference-count":17,"publisher":"Akademiai Kiado Zrt.","issue":"15","license":[{"start":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:00:00Z","timestamp":1744502400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,4,13]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic> Olyan seb\u00e9szeti oszt\u00e1lyokon, ahol kell\u0151 sz\u00e1m\u00fa\n                    pajzsmirigym\u0171t\u00e9tet v\u00e9geznek, viszonylag ritka sz\u00f6vettani diagn\u00f3zisokkal is lehet\n                    tal\u00e1lkozni. E sz\u00f6vettani diagn\u00f3zisok ismerete fontos a k\u00f3reredet meg\u00e9rt\u00e9s\u00e9ben \u00e9s\n                    a betegs\u00e9g ter\u00e1pi\u00e1j\u00e1nak megv\u00e1laszt\u00e1s\u00e1ban. <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    K\u00eds\u00e9rletet tesz\u00fcnk amyloidstruma eset\u00e9ben, gyakoris\u00e1g\u00e1nak meghat\u00e1roz\u00e1s\u00e1ra \u00e9s\n                    t\u00e1rsul\u00f3 k\u00f3rk\u00e9pekkel t\u00f6rt\u00e9n\u0151 \u00f6sszef\u00fcgg\u00e9seinek vizsg\u00e1lat\u00e1ra.\n                        <jats:italic>M\u00f3dszer:<\/jats:italic> 2001 \u00e9s 2023 k\u00f6z\u00f6tt 2215 pajzsmirigym\u0171t\u00e9tet\n                    v\u00e9gezt\u00fcnk a Fej\u00e9r V\u00e1rmegyei Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z \u00c1ltal\u00e1nos\n                    Seb\u00e9szeti Oszt\u00e1ly\u00e1n, Sz\u00e9kesfeh\u00e9rv\u00e1ron. Retrospekt\u00edven vizsg\u00e1ltuk a sz\u00f6vettani\n                    eredm\u00e9nyeket, majd a sz\u00f6vettani vizsg\u00e1lat lelet\u00e9t \u00f6sszevetett\u00fck a beteg\n                    k\u00f3rt\u00f6rt\u00e9net\u00e9vel. <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A 2215 oper\u00e1lt esetb\u0151l mind\u00f6ssze 2\n                    esetben volt a sz\u00f6vettani diagn\u00f3zis amyloidstruma, mely az \u00f6sszes eset mind\u00f6ssze\n                    0,09%-a. <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic> Amyloidstruma rendszerint valamilyen\n                    egy\u00e9b k\u00f3rk\u00e9ppel t\u00e1rsulva jelenik meg. Eseteinkben kr\u00f3nikus veseel\u00e9gtelens\u00e9g,\n                    tart\u00f3s dial\u00edziskezel\u00e9s mellett, illetve gyullad\u00e1sos b\u00e9lbetegs\u00e9g (morbus Crohn)\n                    k\u00eds\u00e9r\u0151jek\u00e9nt. A m\u0171t\u00e9ti indik\u00e1ci\u00f3t a megnagyobbodott pajzsmirigy \u00e1ltal okozott\n                    mechanikus kompresszi\u00f3 k\u00e9pezte. <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> Ismeretlen\n                    eredet\u0171 diff\u00faz, kompresszi\u00f3s t\u00fcneteket okoz\u00f3 struma eset\u00e9n gondolni lehet\n                    j\u00f3indulat\u00fa amyloidstrum\u00e1ra, de a pontos diagn\u00f3zis t\u00f6bbnyire csak a m\u0171t\u00e9ti\n                    prepar\u00e1tum sz\u00f6vettani feldolgoz\u00e1s\u00e1val tiszt\u00e1z\u00f3dik. A tot\u00e1lis thyreoidectomia\n                    megsz\u00fcnteti a beteg panaszait. Orv Hetil. 2025; 166(15): 588\u2013591.<\/jats:p>","DOI":"10.1556\/650.2025.33269","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T22:04:19Z","timestamp":1744668259000},"page":"588-591","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Amyloidstruma seb\u00e9szeti oszt\u00e1lyunk anyag\u00e1ban"],"prefix":"10.1556","volume":"166","author":[{"given":"Zolt\u00e1n","family":"Farsang","sequence":"first","affiliation":[{"name":"Fej\u00e9r V\u00e1rmegyei Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z, \u00c1ltal\u00e1nos Seb\u00e9szeti Oszt\u00e1ly Sz\u00e9kesfeh\u00e9rv\u00e1r, Sereg\u00e9lyesi \u00fat 3., 8000 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zs\u00f3fia","family":"P\u00e1ncz\u00e9l","sequence":"additional","affiliation":[{"name":"Fej\u00e9r V\u00e1rmegyei Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z, \u00c1ltal\u00e1nos Seb\u00e9szeti Oszt\u00e1ly Sz\u00e9kesfeh\u00e9rv\u00e1r, Sereg\u00e9lyesi \u00fat 3., 8000 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Szil\u00e1gyi","sequence":"additional","affiliation":[{"name":"Fej\u00e9r V\u00e1rmegyei Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z, Patol\u00f3giai Oszt\u00e1ly Sz\u00e9kesfeh\u00e9rv\u00e1r Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Vereczkei","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ron","family":"Altorjay","sequence":"additional","affiliation":[{"name":"Fej\u00e9r V\u00e1rmegyei Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z, \u00c1ltal\u00e1nos Seb\u00e9szeti Oszt\u00e1ly Sz\u00e9kesfeh\u00e9rv\u00e1r, Sereg\u00e9lyesi \u00fat 3., 8000 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1 Villa F, Dionigi G, Tanda ML, et al. Amyloid goiter. Int J Surg. 2008; 6(Suppl 1): S16-S18.","DOI":"10.1016\/j.ijsu.2008.12.025"},{"key":"ref1","unstructured":"2 Lapis K. (ed.) Pathology I-III. [Pathologia I-III.] Medicina K\u00f6nyvkiad\u00f3, Budapest, 1989; p. 91. [Hungarian]"},{"key":"ref2","unstructured":"3 Von Rokitansky C. Textbook of pathological anatomy. [Lehrbuch der pathologischen Anatomie.] 3rd ed. Vol. 1. Braum\u00fcller Verlag, Vienna, 1855; pp. 326-328. [German]"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.3324\/haematol.2009.008912","article-title":"Current treatment of AL amyloidosis","volume":"94","author":"Palladini G","year":"2009","unstructured":"4 Palladini G, Merlini G. Current treatment of AL amyloidosis. Haematologica 2009; 94: 1044-1048.","journal-title":"Haematologica"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1093\/ajcp\/36.4.341","article-title":"Review of the literature and report of a case","volume":"36","author":"Arean VM","year":"1961","unstructured":"5 Arean VM, Klein RE. Amyloid goiter. Review of the literature and report of a case. Am J Clin Pathol. 1961; 36: 341-355.","journal-title":"Am J Clin Pathol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1385\/EP:15:1:89","article-title":"Amyloid goiter with hyperthyroidism","volume":"15","author":"6 Tokyol","year":"2004","unstructured":"6 Tokyol C, Demir S, Yilmaz S, et al. Amyloid goiter with hyperthyroidism. Endocr Pathol. 2004; 15: 89-90.","journal-title":"Endocr Pathol"},{"key":"ref6","unstructured":"7 Levillain P, Piard F, Justrabo E, et al. Amyloid goiter. Apropos of a case. [Le goitre amylo\u00efde. A propos d'un cas.] Arch Anat Cytol Pathol. 1985; 33: 145-148. [French]"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8 R\u00e9ti Z, T\u0151ke J, Balla R, et al. Diagnosis and treatment of medullary thyroid cancer in four Hungarian university centers (2000-2023). [A medullaris pajzsmirigyr\u00e1k diagnosztik\u00e1ja \u00e9s kezel\u00e9se n\u00e9gy magyarorsz\u00e1gi egyetemi centrumban (2000-2023).] Orv Hetil. 2024; 165: 1735-1745. [Hungarian]","DOI":"10.1556\/650.2024.33173"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1007\/s00405-013-2777-5","article-title":"Primary amyloid goiter mimicking rapid growing thyroid malignancy","volume":"271","author":"9 Joung","year":"2014","unstructured":"9 Joung KH, Park JY, Kim KS, et al. Primary amyloid goiter mimicking rapid growing thyroid malignancy. Ear Arch Otorhinolaryngol. 2014; 271: 417-420.","journal-title":"Ear Arch Otorhinolaryngol"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10 Farsang Z, Jask\u00f3 R, R\u00e9v\u00e9sz E, et al. Safety-driven radical approaches in routine thyroid surgery: roles and challenges. [A biztons\u00e1gra t\u00f6rekv\u0151 radikalit\u00e1s helye, szerepe \u00e9s dilemm\u00e1i a pajzsmirigyseb\u00e9szet mindennapjaiban.] Orv Hetil. 2024; 165: 1548-1557. [Hungarian]","DOI":"10.1556\/650.2024.33132"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1089\/thy.2006.0045","article-title":"Amyloid goiter as a manifestation of primary systemic amyloidosis","volume":"17","author":"11 Siddiqui","year":"2007","unstructured":"11 Siddiqui MA, Gertz M, Dean D. Amyloid goiter as a manifestation of primary systemic amyloidosis. Thyroid 2007; 17: 77-80.","journal-title":"Thyroid"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12 Pinto A, Nos\u00e9 V. Localized amyloid in thyroid: are we missing it? Adv Anat Pathol. 2013; 20: 61-67.","DOI":"10.1097\/PAP.0b013e31827b6519"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.anorl.2010.02.013","article-title":"Amyloid goiter: first manifestation of systemic amyloidosis","volume":"127","author":"13 Kazdaghli Lagha","year":"2010","unstructured":"13 Kazdaghli Lagha E, M'Sakni I, Bougrine F, et al. Amyloid goiter: first manifestation of systemic amyloidosis. Eur Ann Otorhinolaryngol Head Neck Dis. 2010; 127: 108-110.","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"ref13","unstructured":"14 Amyloidosis. In: Herold G. et al. (eds.) Internal medicine. [Amyloidosis. In: Herold G, \u00e9s mtsai (szerk.) Belgy\u00f3gy\u00e1szat.] Medicina K\u00f6nyvkiad\u00f3, Budapest, 2009; pp. 142-146. [Hungarian]"},{"key":"ref14","unstructured":"15 Magyar I, Petr\u00e1nyi Gy. Basic lines of internal medicine I-III. (A belgy\u00f3gy\u00e1szat alapvonalai I-III.) Medicina K\u00f6nyvkiad\u00f3, Budapest, 1986; pp. 1701-1702. [Hungarian]"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1002\/lary.21459","article-title":"Amyloid goiter: a case of primary thyroid amyloid disease","volume":"121","author":"16 Sethi","year":"2011","unstructured":"16 Sethi Y, Gulati A, Singh I, et al. Amyloid goiter: a case of primary thyroid amyloid disease. Laryngoscope 2011; 121: 961-964.","journal-title":"Laryngoscope"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1136\/pgmj.58.677.171","article-title":"Fast growing goitre as a first clinical manifestation of systemic amyloidosis","volume":"58","author":"17 Amado","year":"1982","unstructured":"17 Amado JA, Palacios S, Manzanos J, et al. Fast growing goitre as a first clinical manifestation of systemic amyloidosis. Postgrad Med J. 1982; 58: 171-172.","journal-title":"Postgrad Med J"}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/166\/15\/article-p588.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/166\/15\/article-p588.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/166\/15\/article-p588.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T08:22:37Z","timestamp":1760516557000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/166\/15\/article-p588.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,13]]},"references-count":17,"journal-issue":{"issue":"15"},"URL":"https:\/\/doi.org\/10.1556\/650.2025.33269","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"type":"print","value":"0030-6002"},{"type":"electronic","value":"1788-6120"}],"subject":[],"published":{"date-parts":[[2025,4,13]]}}}