{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T04:39:44Z","timestamp":1779079184010,"version":"3.51.4"},"reference-count":41,"publisher":"Akademiai Kiado Zrt.","issue":"15","license":[{"start":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:00:00Z","timestamp":1744502400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,4,13]]},"abstract":"<jats:p>A hasny\u00e1lmirigy szokatlan helye a daganatos \u00e1tt\u00e9tek (szekunder daganatok)\n                    kialakul\u00e1s\u00e1nak. A hasny\u00e1lmirigyet \u00e9rint\u0151 \u00e1tt\u00e9tes megbeteged\u00e9s lehet izol\u00e1lt vagy\n                    diff\u00faz, m\u00edg a megjelen\u00e9s alapj\u00e1n szinkr\u00f3n vagy metakr\u00f3n. A k\u00fcl\u00f6nb\u00f6z\u0151 szekunder\n                    pancreasdaganatok progn\u00f3zisa a primer daganatt\u00f3l f\u00fcgg\u0151en v\u00e1ltoz\u00f3. Az irodalmi\n                    \u00e1ttekint\u00e9s c\u00e9lja, hogy k\u00e9pet adjon a hasny\u00e1lmirigyben kialakul\u00f3 \u00e1tt\u00e9tekr\u0151l \u00e9s\n                    azok ter\u00e1pi\u00e1s lehet\u0151s\u00e9geir\u0151l. A szakirodalom retrospekt\u00edv \u00e1ttekint\u00e9s\u00e9t v\u00e9gezt\u00fck\n                    a 2014 \u00e9s 2023 k\u00f6z\u00f6tti id\u0151szakra vonatkoz\u00f3an a PubMed adatb\u00e1zis haszn\u00e1lat\u00e1val.\n                    Az \u00edgy nyert adatokb\u00f3l a szekunder pancreasdaganatokat elemezt\u00fck el\u0151fordul\u00e1si\n                    gyakoris\u00e1guk, az \u00e1tt\u00e9tet ad\u00f3 els\u0151dleges malignus daganatok, a klinikai t\u00fcnetek,\n                    k\u00f3rism\u00e9j\u00fck, a kialakul\u00e1si mechanizmusok \u00e9s a kezel\u00e9si elvek alapj\u00e1n. A pancreas\n                    szekunder daganatai ritk\u00e1k, a malignus hasny\u00e1lmirigy-daganatok 2\u20135%-\u00e1t alkotj\u00e1k.\n                    A vil\u00e1gos sejtes vesesejtes carcinoma okoz a leggyakrabban \u00e1tt\u00e9tet a\n                    hasny\u00e1lmirigyben. A pancreas szekunder daganatai gyakran t\u00fcnetmentesek, a\n                    k\u00f3risme fel\u00e1ll\u00edt\u00e1sa neh\u00e9z, \u00f6sszet\u00e9veszthet\u0151k a primer daganatokkal, ez\u00e9rt\n                    sz\u00fcks\u00e9gesek a sz\u00f6vettani \u00e9s immunhisztok\u00e9miai vizsg\u00e1latok. A m\u00e1sodlagos\n                    hasny\u00e1lmirigy-daganatok kialakul\u00e1s\u00e1ban a sziszt\u00e9m\u00e1s-hematog\u00e9n mechanizmus az\n                    elfogadott. A seb\u00e9szeti kezel\u00e9s meghosszabb\u00edtja a t\u00fal\u00e9l\u00e9st, a sziszt\u00e9m\u00e1s,\n                    molekul\u00e1ris c\u00e9lzott ter\u00e1pia alkalmaz\u00e1sa az ut\u00f3bbi id\u0151ben hat\u00e9konynak bizonyult.\n                    Orv Hetil. 2025; 166(15): 563\u2013568.<\/jats:p>","DOI":"10.1556\/650.2025.33276","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T22:04:20Z","timestamp":1744668260000},"page":"563-568","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["A hasny\u00e1lmirigy \u00e1tt\u00e9tes daganatai \u2013 kialakul\u00e1sukt\u00f3l a ter\u00e1pi\u00e1s lehet\u0151s\u00e9gekig"],"prefix":"10.1556","volume":"166","author":[{"given":"Tivadar","family":"Bara","sequence":"first","affiliation":[{"name":"II. Department of Surgery, \u201eGeorge Emil Palade\u201d University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u0219 T\u00e2rgu Mure\u0219 Romania"},{"name":"Maros Megyei S\u00fcrg\u0151ss\u00e9gi Klinikai K\u00f3rh\u00e1z, II. Seb\u00e9szeti Klinika Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"F\u00fcl\u00f6p","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika Szeged, Magyarorsz\u00e1g Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mircea Gabriel","family":"Muresan","sequence":"additional","affiliation":[{"name":"Department of Anatomy, \u201eGeorge Emil Palade\u201d University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u0219 T\u00e2rgu Mure\u0219 Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tivadar","family":"Bara","sequence":"additional","affiliation":[{"name":"Maros Megyei S\u00fcrg\u0151ss\u00e9gi Klinikai K\u00f3rh\u00e1z, II. 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Pancreatic cancer with liver metastases: is it possible to improve survival by resection of oligopersistent primary tumor following neoadjuvant chemotherapy? [M\u00e1j\u00e1tt\u00e9tes pancreasr\u00e1k: meghosszabb\u00edthat\u00f3-e a t\u00fal\u00e9l\u00e9s az oligoperzisztens primer daganat neoadjuv\u00e1ns kemoter\u00e1pi\u00e1t k\u00f6vet\u0151 reszekci\u00f3j\u00e1val?] Orv Hetil. 2023; 164: 1712-1718. 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