{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:06:09Z","timestamp":1785528369935,"version":"3.56.0"},"reference-count":23,"publisher":"Akademiai Kiado Zrt.","issue":"25","license":[{"start":{"date-parts":[[2025,6,22]],"date-time":"2025-06-22T00:00:00Z","timestamp":1750550400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Eur\u00f3pai Uni\u00f3 Helyre\u00e1ll\u00edt\u00e1si \u00e9s Ellen\u00e1ll\u00f3k\u00e9pess\u00e9gi Eszk\u00f6z","award":["RRF-2.3.1-21-2022-00011"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00011"]}]}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,6,22]]},"abstract":"<jats:p>\n                    <jats:italic>Bevezet\u00e9s:<\/jats:italic>\n                    Az \u00fajsz\u00fcl\u00f6ttkori hypoxi\u00e1s-ischaemi\u00e1s encephalopathi\u00e1t\n                    neurol\u00f3giai k\u00e1rosod\u00e1s n\u00e9lk\u00fcl t\u00fal\u00e9lt gyermekek kognit\u00edv funkci\u00f3inak (p\u00e9ld\u00e1ul\n                    nyelvi fejl\u0151d\u00e9s) r\u00e9szletes megismer\u00e9s\u00e9r\u0151l kev\u00e9s irodalmi adat \u00e1ll rendelkez\u00e9sre.\n                    <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    A korai nyelvi fejl\u0151d\u00e9si k\u00e9s\u00e9s gyakoris\u00e1g\u00e1nak\n                    felt\u00e1r\u00e1sa \u00e9s a nyelvi fejl\u0151d\u00e9s saj\u00e1toss\u00e1gainak megismer\u00e9se a hypoxi\u00e1s-ischaemi\u00e1s\n                    encephalopathia min\u0151s\u00e9gi t\u00fal\u00e9l\u0151in\u00e9l.\n                    <jats:italic>M\u00f3dszer:<\/jats:italic>\n                    Olyan\n                    hypothermi\u00e1s kezel\u00e9sben r\u00e9szes\u00fclt, k\u00f6z\u00e9ps\u00falyos-s\u00falyos hypoxi\u00e1s-ischaemi\u00e1s\n                    encephalopathi\u00e1t t\u00fal\u00e9lt gyermekek ker\u00fcltek a 2017 \u00e9s 2020 k\u00f6z\u00f6tt zajlott\n                    prospekt\u00edv vizsg\u00e1latba, akik r\u00e9szt vettek a 2 \u00e9ves kori fejl\u0151d\u00e9si ut\u00e1nk\u00f6vet\u00e9si\n                    vizsg\u00e1laton. Az ut\u00e1nk\u00f6vet\u00e9si vizsg\u00e1laton a Bayley-II. fejl\u0151d\u00e9si (kognit\u00edv)\n                    sk\u00e1l\u00e1t alkalmaztuk (kedvez\u0151tlen kognit\u00edv fejl\u0151d\u00e9si kimenet\u0171 \u226485 pont). A nyelvi\n                    fejl\u0151d\u00e9s vizsg\u00e1lat\u00e1ra a MacArthur\u2013Bates Kommunikat\u00edv Fejl\u0151d\u00e9si Adatt\u00e1r: Szavak\n                    \u00e9s Mondatok k\u00e9rd\u0151\u00edvet alkalmaztuk. Korai nyelvi fejl\u0151d\u00e9si k\u00e9s\u00e9st defini\u00e1ltunk\n                    azokn\u00e1l, akikn\u00e9l az \u00e1tlagos kognit\u00edv fejletts\u00e9g mellett az expressz\u00edv nyelvi\n                    sz\u00f3kincs 20 percentilis al\u00e1 esett.\n                    <jats:italic>Eredm\u00e9nyek:<\/jats:italic>\n                    A vizsg\u00e1latba\n                    bevont 50 csecsem\u0151 k\u00f6z\u00fcl kedvez\u0151tlen kognit\u00edv fejl\u0151d\u00e9si kimenetel 46%-ban\n                    (23\/50), kedvez\u0151 kimenetel 54%-ban (27\/50) fordult el\u0151. A kedvez\u0151 kognit\u00edv\n                    fejl\u0151d\u00e9s\u0171 gyermekek (n = 27) k\u00f6z\u00f6tt 10 gyermekn\u00e9l korai nyelvi k\u00e9s\u00e9s, 17-n\u00e9l\n                    norm\u00e1l nyelvi fejl\u0151d\u00e9s mutatkozott. A korai nyelvi k\u00e9s\u00e9s 20%-ban (10\/50) fordult\n                    el\u0151, ami magasabb a norm\u00e1lpopul\u00e1ci\u00f3n\u00e1l megfigyelt 10\u201315%-os el\u0151fordul\u00e1si\n                    ar\u00e1nyhoz k\u00e9pest. A medi\u00e1n (IQR) sz\u00f3kincs nagys\u00e1ga a megk\u00e9sett nyelvi fejl\u0151d\u00e9s\u0171ek\n                    eset\u00e9n 30 [20; 70], a norm\u00e1l nyelvi fejl\u0151d\u00e9s\u0171ekn\u00e9l 250 [159; 565] sz\u00f3 volt\n                    (p&lt;0,001), a k\u00e9t csoport minden nyelvi mutat\u00f3 (p\u00e9ld\u00e1ul morf\u00e9mahaszn\u00e1lat,\n                    sz\u00f3kapcsolatok) ment\u00e9n elt\u00e9rt egym\u00e1st\u00f3l.\n                    <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic>\n                    A\n                    hypoxi\u00e1s-ischaemi\u00e1s encephalopathi\u00e1t \u00e1t\u00e9lt min\u0151s\u00e9gi t\u00fal\u00e9l\u0151k eset\u00e9ben az\n                    \u00e1tlagpopul\u00e1ci\u00f3n\u00e1l gyakoribb a korai nyelvi fejl\u0151d\u00e9si k\u00e9s\u00e9s el\u0151fordul\u00e1sa.\n                    Eredm\u00e9nyeink alapj\u00e1n a nyelv elt\u00e9r\u0151 szintjei, \u00edgy a lexik\u00e1lis \u00e9s a nyelvtani\n                    szint is \u00e9rintett a korai nyelvi fejl\u0151d\u00e9si k\u00e9s\u00e9st mutat\u00f3, \u00e1m kedvez\u0151 kognit\u00edv\n                    fejl\u0151d\u00e9si kimenetel\u0171 hypoxi\u00e1s-ischaemi\u00e1s encephalopathi\u00e1s gyermekekn\u00e9l.\n                    <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic>\n                    Eredm\u00e9nyeink alapj\u00e1n a kedvez\u0151 kognit\u00edv\n                    fejl\u0151d\u00e9s\u0171 gyermekek eset\u00e9ben is fontos az olyan ter\u00fcletspecifikus funkci\u00f3k\n                    vizsg\u00e1lata, mint a nyelvi fejl\u0151d\u00e9s, hiszen a gondolkod\u00e1si funkci\u00f3k \u00e1tlagos\n                    szintj\u00e9b\u0151l nem k\u00f6vetkezik automatikusan a nyelvi appar\u00e1tus \u00e9rintetlens\u00e9ge ebben\n                    a specifikus betegpopul\u00e1ci\u00f3ban. Orv Hetil. 2025; 166(25): 990\u2013999.\n                  <\/jats:p>","DOI":"10.1556\/650.2025.33323","type":"journal-article","created":{"date-parts":[[2025,6,22]],"date-time":"2025-06-22T05:33:37Z","timestamp":1750570417000},"page":"990-999","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["A korai nyelvi fejl\u0151d\u00e9si k\u00e9s\u00e9s vizsg\u00e1lata \u00fajsz\u00fcl\u00f6ttkori hypoxi\u00e1s-ischaemi\u00e1s encephalopathi\u00e1t neurol\u00f3giai k\u00e1rosod\u00e1s n\u00e9lk\u00fcl t\u00fal\u00e9lt gyermekekben"],"prefix":"10.1556","volume":"166","author":[{"given":"Anna","family":"Bolod\u00e1r","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Nagy","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Budapest, B\u00f3kay J. u. 53., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00f3ra Luca","family":"Bod\u00f3cs","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Transzl\u00e1ci\u00f3s Medicina Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Ruszny\u00e1k","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1gnes","family":"Jermendy","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Budapest, B\u00f3kay J. u. 53., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikl\u00f3s","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Budapest, B\u00f3kay J. u. 53., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Varga","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Budapest, B\u00f3kay J. u. 53., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Kurinczuk JJ, White-Koning M, Badawi N. 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