{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:02:28Z","timestamp":1785427348182,"version":"3.56.0"},"reference-count":21,"publisher":"Akademiai Kiado Zrt.","issue":"31","license":[{"start":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T00:00:00Z","timestamp":1754179200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"HUN\u00adREN\u00ad OOI\u00adTTK\u00adHCEMM Onkogenomikai Kutat\u00f3csoport"},{"name":"SZTE SZAOK, Patholo\u00adgiai Int\u00e9zet"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,8,3]]},"abstract":"\n A perirenalis zs\u00edrsz\u00f6vetben ritk\u00e1n kialakul\u00f3, incident\u00e1lisan felfedezett myxoid\n pseudotumorok a r\u00e9gi\u00f3 szint\u00e9n ritka benignus \u00e9s malignus daganatait\n ut\u00e1nozhatj\u00e1k, emiatt sz\u00f6vettani ismeret\u00fck kiemelten fontos. K\u00f6zlem\u00e9ny\u00fcnkben egy\n 38 \u00e9ves f\u00e9rfi eset\u00e9t mutatjuk be, akin\u00e9l bilater\u00e1lis vesicoureteralis reflux \u00e9s\n bal oldali hydronephrosis talaj\u00e1n v\u00e9gst\u00e1dium\u00fa vesebetegs\u00e9g alakult ki, amely\n miatt veseallograft-be\u00fcltet\u00e9s t\u00f6rt\u00e9nt. 19 \u00e9vvel a transzplant\u00e1ci\u00f3t k\u00f6vet\u0151en\n graftectomia v\u00e1lt sz\u00fcks\u00e9gess\u00e9. A sz\u00f6vettani feldolgoz\u00e1s sor\u00e1n a v\u00e9gst\u00e1dium\u00fa\n vesebetegs\u00e9g sz\u00f6veti k\u00e9pe mellett a vesekapuban k\u00f6r\u00fcl\u00edrt, myxoid ter\u00fcleteket\n tartalmaz\u00f3 ors\u00f3sejtes prolifer\u00e1ci\u00f3t \u00e9szlelt\u00fcnk. A citol\u00f3giai at\u00edpia hi\u00e1nya \u00e9s az\n immunhisztok\u00e9miai reakci\u00f3k alapj\u00e1n a laesi\u00f3t a perirenalis zs\u00edrsz\u00f6vet myxoid\n pseudotumor\u00e1nak v\u00e9lem\u00e9nyezt\u00fck. Az ismeretlen patogenezis\u0171 betegs\u00e9g tumoros \u00e9s\n nem tumoros vesebetegs\u00e9gekhez t\u00e1rsultan alakul ki. Az eddigi adatok alapj\u00e1n\n j\u00f3indulat\u00fa tumorszer\u0171 laesi\u00f3r\u00f3l van sz\u00f3, \u00e9s elt\u00e1vol\u00edt\u00e1st k\u00f6vet\u0151 ki\u00fajul\u00e1sr\u00f3l\n eddig m\u00e9g nem sz\u00e1moltak be. A ritka entit\u00e1s a leggyakrabban j\u00f3l differenci\u00e1lt\n liposarcom\u00e1ra hasonl\u00edt, amelynek elk\u00fcl\u00f6n\u00edt\u00e9s\u00e9ben a morfol\u00f3gia, az immunprofil,\n valamint az\n MDM2<\/jats:italic>\n -FISH-vizsg\u00e1lat seg\u00edt. A jelen esetben a\n perirenalis myxoid pseudotumorban a FISH-vizsg\u00e1lat sem jelzett a tumorsejtekben\n MDM2<\/jats:italic>\n g\u00e9namplifik\u00e1ci\u00f3t. Orv Hetil. 2025; 166(31):\n 1224\u20131229.\n <\/jats:p>","DOI":"10.1556\/650.2025.33342","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T21:53:46Z","timestamp":1754344426000},"page":"1224-1229","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["A perirenalis zs\u00edrsz\u00f6vet myxoid pseudotumora"],"prefix":"10.1556","volume":"166","author":[{"given":"Bogl\u00e1rka","family":"P\u00f3sfai","sequence":"first","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Jenei","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Pancsa","sequence":"additional","affiliation":[{"name":"Eurofins-Medserv Kft. Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levente","family":"Kuthi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"},{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Tumorpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest Magyarorsz\u00e1g"},{"name":"HUN-REN-OOI-TTK-HCEMM Onkogenomikai Kutat\u00f3csoport, Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Tanas MR, Sthapanachai C, Nonaka D, et al. Pseudosarcomatous\n fibroblastic\/myofibroblastic proliferation in perinephric adipose tissue\n adjacent to renal cell carcinoma: a lesion mimicking well-differentiated\n liposarcoma. Mod Pathol. 2009; 22: 1196\u20131200.","DOI":"10.1038\/modpathol.2009.84"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Dashti NK, Fritchie KJ, Folpe AL. Perinephric myxoid pseudotumor of\n fat: a distinctive pseudoneoplasm most often associated with non-neoplastic\n renal disease. Hum Pathol. 2019; 87: 37\u201343.","DOI":"10.1016\/j.humpath.2019.02.005"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Thoeni C, Ordon M, Krizova A, et al. Perinephric myxoid pseudotumour\n of fat. First described case in allograft kidney, a mimicker of malignancy.\n Histopathology 2021; 79: 1108\u20131110.","DOI":"10.1111\/his.14382"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Pham M, Janiszewski RA, Stanton ML, et al. Renal transplants with\n perinephric myxoid pseudotumor of fat mimicking malignancy. Jpn J Clin Oncol.\n 2022; 52: 654\u2013655. Erratum: Jpn J Clin Oncol. 2022; 52: 1358.","DOI":"10.1093\/jjco\/hyac038"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Liu RW, Tan G, Lim YT, et al. Perinephric myxoid pseudotumor of fat\n in a young patient with a horseshoe kidney complicated by an obstructing renal\n calculus. Asian J Urol. 2023; 10: 382\u2013384.","DOI":"10.1016\/j.ajur.2022.04.007"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Amato M, Piazza P, Ferrari I, et al. Rare perinephric myxoid\n pseudotumor of fat causing ureteropelvic junction obstruction: a case report.\n CEN Case Rep. 2023; 12: 210\u2013214.","DOI":"10.1007\/s13730-022-00746-7"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Hogan K, McKenney JK, Cox RM, et al. Myxoid pseudotumor involving\n the renal sinus: clinicopathologic study of 33 cases supporting a distinct\n benign non-neoplastic lesion. Am J Surg Pathol. 2023; 47:\n 218\u2013223.","DOI":"10.1097\/PAS.0000000000001968"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"P\u00f3sfai B, S\u00e1nta F, Schubert A, et al. Morphological variants of the\n invasive urothelial cell carcinoma. [Az invaz\u00edv urothelsejtes carcinoma\n morfol\u00f3giai vari\u00e1nsai.] Orv Hetil. 2023; 164: 1567\u20131582.\n [Hungarian]","DOI":"10.1556\/650.2023.32881"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Ortiz-Rey JA, Garc\u00eda-Baiz\u00e1n A, Bellas-Pereira A, et al. Myxoid\n pseudotumor changes affecting the distal ureter associated with urothelial\n carcinoma in situ. Int J Surg Pathol. 2024; 32: 772\u2013775.","DOI":"10.1177\/10668969231188894"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Wu Q, Baraban E, Gross JM. Perinephric myxoid pseudotumor of fat. A\n series of 13 cases and literature review. Hum Pathol. 2024; 154:\n 105681.","DOI":"10.1016\/j.humpath.2024.105681"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Kallen ME, Drachenberg CB, Legesse TB. Lesson of the month:\n perinephric myxoid pseudotumor of fat co-occurring with polycystic kidney\n disease. Histopathology 2024; 85: 521\u2013522.","DOI":"10.1111\/his.15210"},{"key":"R12","doi-asserted-by":"crossref","unstructured":"Schnoz C, Bonani M, Huber FA, et al. Perinephric myxoid pseudotumor\n of fat. Histopathological and molecular characterization of 3 cases after renal\n transplantation. Diagn Pathol. 2025; 20: 25.","DOI":"10.1186\/s13000-025-01615-4"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Campo-Verde-Arbocco F, L\u00f3pez-Laur JD, Romeo LR, et al. Human renal\n adipose tissue induces the invasion and progression of renal cell carcinoma.\n Oncotarget 2017; 8: 94223\u201394234.","DOI":"10.18632\/oncotarget.21666"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"Lee J, King KG, Chopra S, et al. Perinephric myxoid pseudotumor of\n fat: a multimodality imaging case series. Abdom Radiol (NY) 2023; 48: 1820\u20131830.\n Erratum: Abdom Radiol (NY) 2023; 48: 1831\u20131839.","DOI":"10.1007\/s00261-022-03747-3"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Broski SM, Knight JA, Larsen BT, et al. Imaging features of\n perinephric myxoid pseudotumors of fat. Abdom Radiol (NY) 2024; 49:\n 3107\u20133116.","DOI":"10.1007\/s00261-024-04294-9"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Setsu N, Miyake M, Wakai S, et al. Primary retroperitoneal myxoid\n liposarcomas. Am J Surg Pathol. 2016; 40: 1286\u20131290.","DOI":"10.1097\/PAS.0000000000000657"},{"key":"R17","doi-asserted-by":"crossref","unstructured":"Lewis DJ, Moul JW, Williams SC, et al. Perirenal liposarcoma\n containing extramedullary hematopoiesis assciated with renal cell carcinoma.\n Urology 1994; 43: 106\u2013109.","DOI":"10.1016\/S0090-4295(94)80279-3"},{"key":"R18","unstructured":"Williamson JM, Konig TC, Canelo R. Incidental finding of renal cell\n carcinoma in recurrent retroperitoneal liposarcoma. Ann R Col Surg Engl. 2008;\n 90: W4\u2013W5."},{"key":"R19","doi-asserted-by":"crossref","unstructured":"Akbarzadeh M, Pancsa T, Sejben A. Evaluation of morphological\n patterns and immunohistochemical characteristics of well-differentiated and\n dedifferentiated liposarcomas. [A j\u00f3l \u00e9s a dedifferenci\u00e1lt liposarcom\u00e1k\n morfol\u00f3giai \u00e9s immunhisztok\u00e9miai jellegzetess\u00e9gei.] Orv Hetil. 2024; 165:\n 1700\u20131706. 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