{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T09:20:17Z","timestamp":1787563217447,"version":"build-2736575974"},"reference-count":74,"publisher":"Akademiai Kiado Zrt.","issue":"39","license":[{"start":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:00:00Z","timestamp":1759017600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,9,28]]},"abstract":"<jats:p>A sarl\u00f3sejtes anaemia homozig\u00f3ta form\u00e1ban s\u00falyos betegs\u00e9g, amely az \u00e9lettartamot\n                    az afroamerikai popul\u00e1ci\u00f3ban \u00e9vtizedekkel ezel\u0151tt m\u00e9g jelent\u0151sen megr\u00f6vid\u00edtette.\n                    Ez a haemoglobinopathia j\u00e1r az ismert hematol\u00f3giai elt\u00e9r\u00e9sek k\u00f6z\u00fcl a legt\u00f6bb,\n                    vascularis talajon kialakul\u00f3 idegrendszeri, cardiovascularis, pulmonalis,\n                    renalis, infekt\u00edv \u00e9s mozg\u00e1sszervi sz\u00f6v\u0151dm\u00e9nnyel, ez\u00e9rt \u00f6sszehangolt \u00e9s integr\u00e1lt\n                    szoros egy\u00fcttm\u0171k\u00f6d\u00e9st k\u00edv\u00e1n a hematol\u00f3gus, a belgy\u00f3gy\u00e1sz, a kardiol\u00f3gus, az\n                    ideggy\u00f3gy\u00e1sz, a szem\u00e9sz, a sz\u00fcl\u00e9sz \u00e9s a gyermekgy\u00f3gy\u00e1sz r\u00e9sz\u00e9r\u0151l. A\n                    multidiszciplin\u00e1ris megk\u00f6zel\u00edt\u00e9s \u00e9s a g\u00e9nm\u00f3dos\u00edt\u00f3 kezel\u00e9sek az ut\u00f3bbi id\u0151ben\n                    jav\u00edtott\u00e1k a t\u00fal\u00e9l\u00e9st \u00e9s az \u00e9letmin\u0151s\u00e9get. Afrika \u00e9s az Amerikai Egyes\u00fclt\n                    \u00c1llamok mellett sz\u00e1mos elt\u00e9r\u0151 fejletts\u00e9g\u0171 orsz\u00e1gban is sok, sarl\u00f3sejtes\n                    anaemi\u00e1ban szenved\u0151 beteggel lehet tal\u00e1lkozni. A haz\u00e1nkban tanul\u00f3 vagy munk\u00e1t\n                    v\u00e1llal\u00f3 szem\u00e9lyek k\u00f6z\u00f6tt is tal\u00e1lkozhatunk a betegs\u00e9ggel, ez\u00e9rt indokolt a\n                    leg\u00fajabb eredm\u00e9nyek \u00e1ttekint\u00e9se. 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