{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:48:46Z","timestamp":1790686126614,"version":"4.1.0"},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"13","license":[{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,3,29]]},"abstract":"<jats:p>Az autol\u00f3g haematopoeticus \u0151ssejt-transzplant\u00e1ci\u00f3 magyarorsz\u00e1gi alapjai az\n                    1980-as \u00e9vek v\u00e9g\u00e9n kezdtek kibontakozni, m\u00e1ra m\u00e1r 6 hazai k\u00f6zpontban is a\n                    hematol\u00f3giai ter\u00e1pia rutinszer\u0171en alkalmazott r\u00e9sze. Az elj\u00e1r\u00e1s jelent\u0151s\n                    szerepet j\u00e1tszik a myeloma multiplex, a Hodgkin- \u00e9s non-Hodgkin-lymphom\u00e1k\n                    kezel\u00e9s\u00e9ben. Tov\u00e1bb\u00e1 a nem hematol\u00f3giai betegs\u00e9gek kezel\u00e9s\u00e9ben is egyre t\u00f6bb\n                    indik\u00e1ci\u00f3ja van. B\u00e1r az autol\u00f3g haematopoeticus \u0151ssejt-transzplant\u00e1ci\u00f3 az\n                    allog\u00e9n \u0151ssejt-transzplant\u00e1ci\u00f3n\u00e1l kevesebb akut sz\u00f6v\u0151dm\u00e9nnyel j\u00e1r, a ter\u00e1pia\n                    sor\u00e1n sz\u00e1mos r\u00f6vid \u00e9s hossz\u00fa t\u00e1v\u00fa cardiovascularis mell\u00e9khat\u00e1s fordulhat el\u0151,\n                    f\u0151k\u00e9nt a nagy d\u00f3zis\u00fa kemoter\u00e1pi\u00e1s el\u0151kezel\u00e9s \u00e9s az alapbetegs\u00e9g kezel\u00e9se kapcs\u00e1n\n                    a megel\u0151z\u0151en alkalmazott, potenci\u00e1lisan cardiotoxicus onkol\u00f3giai ter\u00e1pi\u00e1k\n                    k\u00f6vetkezt\u00e9ben. Mind az akut, a peritranszplant\u00e1ci\u00f3s id\u0151szak \u00e9s az azt k\u00f6vet\u0151 100\n                    nap alatt bek\u00f6vetkez\u0151, mind pedig a k\u00e9s\u0151i (\\&gt;100 nap) cardiovascularis esem\u00e9nyek\n                    el\u0151fordul\u00e1sa jelent\u0151sen gyakoribb, mint a hasonl\u00f3 kor\u00fa \u00e1ltal\u00e1nos popul\u00e1ci\u00f3ban. A\n                    transzplant\u00e1ci\u00f3 sor\u00e1n fell\u00e9p\u0151 major adverz cardiovascularis esem\u00e9nyek\n                    limit\u00e1lhatj\u00e1k a ter\u00e1pia siker\u00e9t, valamint ronthatj\u00e1k a hematol\u00f3giai alapbetegs\u00e9g\n                    progn\u00f3zis\u00e1t \u00e9s a kezelt beteg \u00e9letmin\u0151s\u00e9g\u00e9t is. \u00c9ppen ez\u00e9rt ezek miel\u0151bbi\n                    felismer\u00e9se, el\u0151rejelz\u00e9se fontos, a primer \u00e9s szekunder prevenci\u00f3 alapj\u00e1t\n                    k\u00e9pezi, n\u00f6velve a betegek \u00e9letkil\u00e1t\u00e1sait \u00e9s \u00e9letmin\u0151s\u00e9g\u00e9t. K\u00f6zlem\u00e9ny\u00fcnk c\u00e9lja az\n                    autol\u00f3g haematopoeticus \u0151ssejt-transzplant\u00e1ci\u00f3 potenci\u00e1lis cardiovascularis\n                    mell\u00e9khat\u00e1sainak, ezek monitoroz\u00e1s\u00e1nak \u00e9s megfelel\u0151 ell\u00e1t\u00e1s\u00e1nak \u00f6sszefoglal\u00e1sa\n                    az aktu\u00e1lis nemzetk\u00f6zi hematol\u00f3giai \u00e9s onkokardiol\u00f3giai ir\u00e1nyelvek t\u00fckr\u00e9ben. Orv\n                    Hetil. 2026; 167(13): 490\u2013498.<\/jats:p>","DOI":"10.1556\/650.2026.33480","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T13:20:19Z","timestamp":1774876819000},"page":"490-498","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Az autol\u00f3g \u0151ssejt-transzplant\u00e1ci\u00f3 kapcs\u00e1n fell\u00e9p\u0151 cardiovascularis sz\u00f6v\u0151dm\u00e9nyek"],"prefix":"10.1556","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2295-3106","authenticated-orcid":true,"given":"Zs\u00f3fia","family":"S\u00e1ndor","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Masszi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zs\u00f3fia","family":"Drobni","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Pozsonyi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Kelemen E, J\u00e1nossa M, Triska E, et al. Bone marrow transplantation\n                    in accelerated chronic granulocytic leukaemia using\n                    dibromomannitol\u2011preconditioning instead of total\u2011body irradiation. Leuk Res.\n                    1985; 9: 1009-1015.\n                    https:\/\/doi.org\/10.1016\/0145-2126(85)90071-2","DOI":"10.1016\/0145-2126(85)90071-2"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Fekete S. Remembrance of the scientist, the physician and the\n                    teacher at the 2023 annual meeting of the Hungarian Society of Internal\n                    Medicine. [Dr. Kelemen Endre: Eml\u00e9kez\u00e9s a tud\u00f3sra, az orvosra \u00e9s a tan\u00e1rra a\n                    Magyar Belgy\u00f3gy\u00e1sz T\u00e1rsas\u00e1g 2023\u2011as nagygy\u0171l\u00e9s\u00e9n.] Magy Belorv Arch. 2024; 77:\n                    284-287. [Hungarian]\n                    https:\/\/doi.org\/10.59063\/mba.2024.77.5-6.3","DOI":"10.59063\/mba.2024.77.5-6.3"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Granot N, Storb R. History of hematopoietic cell transplantation:\n                    challenges and progress. Haematologica 2020; 105: 2716-2729.\n                        https:\/\/doi.org\/10.3324\/haematol.2019.245688","DOI":"10.3324\/haematol.2019.245688"},{"key":"R4","unstructured":"Semmelweis University announces availability of stem cell\n                    transplantation. [M\u00e1r a Semmelweis Egyetemen is el\u00e9rhet\u0151 az\n                    \u0151ssejt-transzplant\u00e1ci\u00f3.] Available from:\n                        hhttps:\/\/semmelweis.hu\/hirek\/2024\/12\/11\/mar-a-semmelweis-egyetemen-is-elerheto-az-ossejt-transzplantacio\/\n                    [accessed: Nov 13, 2025]. [Hungarian]"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Sharma SK. 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