{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T17:55:39Z","timestamp":1772387739333,"version":"3.50.1"},"reference-count":15,"publisher":"Akademiai Kiado Zrt.","issue":"9","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:p>A techn\u00e9cium-99m-MIBI (metoxi-izobutil-izonitril) egy radiofarmakol\u00f3giai\n                    k\u00e9sz\u00edtm\u00e9ny, amelyet a sz\u00edv v\u00e9rell\u00e1t\u00e1s\u00e1nak, illetve mell\u00e9kpajzsmirigy-sz\u00f6vetek\n                    patol\u00f3gi\u00e1j\u00e1nak kivizsg\u00e1l\u00e1s\u00e1ra haszn\u00e1lnak. A MIBI-vel v\u00e9gzett szcintigr\u00e1fia\n                    gyakran haszn\u00e1lt diagnosztikus m\u00f3dszer mell\u00e9kpajzsmirigy-adenoma kivizsg\u00e1l\u00e1s\u00e1nak\n                    r\u00e9szek\u00e9nt az elv\u00e1ltoz\u00e1s lokaliz\u00e1l\u00e1s\u00e1ra, esetleg ectopi\u00e1s adenoma kiz\u00e1r\u00e1s\u00e1ra,\n                    azonban pajzsmirigy-adenoma, pajzsmirigyr\u00e1k \u00e9s egy\u00e9b sejtd\u00fas, sok mitokondriumot\n                    tartalmaz\u00f3 elv\u00e1ltoz\u00e1sok is okozhatnak izot\u00f3pd\u00fas\u00edt\u00e1st. Tanulm\u00e1nyunkban egy 79\n                    \u00e9ves n\u0151beteg eset\u00e9t mutatjuk be, aki 1997 \u00f3ta osteoporosis miatt endokrinol\u00f3giai\n                    kezel\u00e9s alatt \u00e1ll. A 2023 v\u00e9g\u00e9t\u0151l intermitt\u00e1l\u00f3 hypercalcaemia \u00e9s emelkedett\n                    parathormonszintek h\u00e1tter\u00e9ben primer hyperparathyreosist v\u00e9lem\u00e9nyezt\u00fcnk. A nyaki\n                    ultrahangvizsg\u00e1lattal \u00e9s a SPECT\/CT-vel kieg\u00e9sz\u00edtett\n                    mell\u00e9kpajzsmirigy-szcintigr\u00e1fi\u00e1s vizsg\u00e1lat a bal als\u00f3\n                    mell\u00e9kpajzsmirigy-adenom\u00e1ra utal\u00f3 elt\u00e9r\u00e9st igazolt, emellett a bal\n                    retro\/parapharyngealis t\u00e9rs\u00e9gben is kifejezett izot\u00f3phalmoz\u00e1s volt l\u00e1that\u00f3, ami\n                    a malignit\u00e1s lehet\u0151s\u00e9g\u00e9t vetette fel. Az MRI alapj\u00e1n a parapharyngealis laesio\n                    malignus jellege nem mer\u00fclt fel. A seb\u00e9szi felt\u00e1r\u00e1s sor\u00e1n a bal fels\u0151\n                    mell\u00e9kpajzsmirigy-adenoma \u00e9s a parapharyngealis t\u00e9rben elhelyezked\u0151 k\u00e9plet\n                    elt\u00e1vol\u00edt\u00e1sra ker\u00fclt, ez ut\u00f3bbi minim\u00e1linvaz\u00edv m\u00f3don, transoralis\n                    endoszk\u00f3passziszt\u00e1lt technik\u00e1val. A sz\u00f6vettani vizsg\u00e1lat\n                    mell\u00e9kpajzsmirigy-adenom\u00e1t, illetve ny\u00e1lmirigy-oncocytom\u00e1t igazolt. Az eset\n                    r\u00e1vil\u00e1g\u00edt a SPECT\/CT-vel kieg\u00e9sz\u00edtett mell\u00e9kpajzsmirigy-szcintigr\u00e1fia\n                    jelent\u0151s\u00e9g\u00e9re a mell\u00e9kpajzsmirigy-adenoma lokaliz\u00e1ci\u00f3s diagnosztik\u00e1j\u00e1ban,\n                    valamint arra, hogy a fokozott izot\u00f3phalmoz\u00e1s nem minden esetben\n                    mell\u00e9kpajzsmirigy-eredet\u0171 elt\u00e9r\u00e9st jelez. Orv Hetil. 2026; 167(9): 351\u2013358.<\/jats:p>","DOI":"10.1556\/650.2026.33482","type":"journal-article","created":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T17:05:22Z","timestamp":1772384722000},"page":"351-358","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Primer hyperparathyreosis SPECT\/CT vizsg\u00e1lattal kieg\u00e9sz\u00edtett szcintigr\u00e1fi\u00e1ja sor\u00e1n radiofarmakon-halmoz\u00e1st mutat\u00f3 parapharyngealis ny\u00e1lmirigy-oncocytoma endoszk\u00f3passziszt\u00e1lt transoralis elt\u00e1vol\u00edt\u00e1sa"],"prefix":"10.1556","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3392-254X","authenticated-orcid":true,"given":"Krist\u00f3f P\u00e9ter","family":"Lud\u00e1nyi","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika Budapest, Szigony u. 36., 1083 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tibor","family":"Szal\u00f3ki","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika Budapest, Szigony u. 36., 1083 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Botond","family":"Hartmayer","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika Budapest, Szigony u. 36., 1083 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szilvia","family":"M\u00e9sz\u00e1ros","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin Krisztina","family":"B\u00fas","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Orvosi K\u00e9palkot\u00f3 Klinika, Nukle\u00e1ris Medicina Tansz\u00e9k Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gl\u00f3ria","family":"Radv\u00e1nszki","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"},{"name":"\u00c9szak-pesti Centrumk\u00f3rh\u00e1z \u2013 Honv\u00e9dk\u00f3rh\u00e1z Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krist\u00f3f Attila","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Korn\u00e9l","family":"D\u00e1nos","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika Budapest, Szigony u. 36., 1083 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Yan X, Li S, Wang L, et al. 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