{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T15:10:43Z","timestamp":1785510643232,"version":"3.56.0"},"reference-count":17,"publisher":"Akademiai Kiado Zrt.","issue":"5","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:p>\n                    <jats:italic>Bevezet\u00e9s:<\/jats:italic>\n                    A s\u00fcrg\u0151ss\u00e9gi oszt\u00e1lyokra kis kock\u00e1zat\u00fa mellkasi\n                    f\u00e1jdalommal \u00e9rkez\u0151 betegek differenci\u00e1ldiagnosztik\u00e1ja vil\u00e1gszerte jelent\u0151s\n                    klinikai \u00e9s eg\u00e9szs\u00e9g-gazdas\u00e1gtani kih\u00edv\u00e1st jelent. B\u00e1r a legt\u00f6bb esetben nem\n                    cardiopulmonalis eredet\u0171 k\u00f3rk\u00e9pek \u00e1llnak a t\u00fcnetek h\u00e1tter\u00e9ben, az ell\u00e1t\u00e1s\n                    els\u0151dleges c\u00e9lja az \u00e9letet vesz\u00e9lyeztet\u0151 \u00e1llapotok \u2013 els\u0151sorban az akut\n                    coronariaszindr\u00f3ma \u00e9s a t\u00fcd\u0151embolia \u2013 gyors \u00e9s biztons\u00e1gos felismer\u00e9se\/kiz\u00e1r\u00e1sa.\n                    A t\u00falzott diagnosztikus vizsg\u00e1latok ugyanakkor n\u00f6velik az ell\u00e1t\u00e1si k\u00f6lts\u00e9geket,\n                    \u00e9s fokozz\u00e1k az oszt\u00e1lyok leterhelts\u00e9g\u00e9t. Kor\u00e1bban publik\u00e1lt megfigyel\u00e9seink\n                    szerint a pleuriticus \u00e9s\/vagy mozg\u00e1sszervi jelleg\u0171 mellkasi f\u00e1jdalommal\n                    jelentkez\u0151 feln\u0151tt betegek k\u00f6r\u00e9ben gyakrabban el\u0151fordul kor\u00e1bban fel nem ismert\n                    gerincaszimmetria, amely a borda\u00edz\u00fcletek (costosternalis, ritk\u00e1bban\n                    costovertebralis) subluxati\u00f3j\u00e1ra hajlamos\u00edthat.\n                    <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    A\n                    tervezett multicentrikus, prospekt\u00edv vizsg\u00e1lat c\u00e9lja a gerincaszimmetria\n                    el\u0151fordul\u00e1s\u00e1nak \u00e9s klinikai jelent\u0151s\u00e9g\u00e9nek meghat\u00e1roz\u00e1sa ambul\u00e1ns, kis\n                    kock\u00e1zat\u00fa, mellkasi f\u00e1jdalommal jelentkez\u0151 feln\u0151ttek k\u00f6r\u00e9ben, valamint egy \u00faj,\n                    mozg\u00e1sszervi eredet\u0171 mellkasi f\u00e1jdalmat azonos\u00edt\u00f3 klinikai predikci\u00f3s modell\n                    fejleszt\u00e9se.\n                    <jats:italic>M\u00f3dszerek:<\/jats:italic>\n                    A vizsg\u00e1lat els\u0151dleges kimeneti\n                    v\u00e1ltoz\u00f3i a t\u00fcd\u0151embolia \u00e9s a major cardialis esem\u00e9nyek (nem ST-elev\u00e1ci\u00f3s\n                    myocardialis infarktus, instabil angina). Kor\u00e1bban valid\u00e1lt sz\u00e1m\u00edt\u00e1s alapj\u00e1n\n                    2500 beteg bevon\u00e1sa biztos\u00edtja a megfelel\u0151 statisztikai er\u0151t a II. t\u00edpus\u00fa hiba\n                    elker\u00fcl\u00e9s\u00e9re. A betegek 30, 90 \u00e9s 365 napos ut\u00e1nk\u00f6vet\u00e9se sor\u00e1n regisztr\u00e1ljuk a\n                    sz\u00f6v\u0151dm\u00e9nyeket, az ism\u00e9telt megjelen\u00e9seket, a major cardialis esem\u00e9nyeket \u00e9s a\n                    mortalit\u00e1st.\n                    <jats:italic>V\u00e1rhat\u00f3 eredm\u00e9nyek:<\/jats:italic>\n                    Felt\u00e9telez\u00e9s\u00fcnk szerint a\n                    gerincaszimmetria jelenl\u00e9te oki \u00f6sszef\u00fcgg\u00e9st mutat az akut, mozg\u00e1sszervi jelleg\u0171\n                    mellkasi f\u00e1jdalommal, amely ebben a betegcsoportban nem j\u00e1r egy\u00fctt emelkedett\n                    mortalit\u00e1si kock\u00e1zattal. Egy \u00fajonnan kidolgozott predikci\u00f3s eszk\u00f6z feltehet\u0151en\n                    lehet\u0151v\u00e9 teheti a mozg\u00e1sszervi eredet\u0171 mellkasi f\u00e1jdalom korai felismer\u00e9s\u00e9t \u00e9s\n                    biztons\u00e1gos elk\u00fcl\u00f6n\u00edt\u00e9s\u00e9t a cardiopulmonalis k\u00f3rk\u00e9pekt\u0151l.\n                    <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic>\n                    A vizsg\u00e1lat eredm\u00e9nyei hozz\u00e1j\u00e1rulhatnak a\n                    s\u00fcrg\u0151ss\u00e9gi betegell\u00e1t\u00e1s diagnosztikus protokollj\u00e1nak finom\u00edt\u00e1s\u00e1hoz, a\n                    sz\u00fcks\u00e9gtelen vizsg\u00e1latok sz\u00e1m\u00e1nak cs\u00f6kkent\u00e9s\u00e9hez, valamint a k\u00f6lts\u00e9ghat\u00e9konys\u00e1g\n                    \u00e9s a betegel\u00e9gedetts\u00e9g jav\u00edt\u00e1s\u00e1hoz. Orv Hetil. 2026; 167(5): 180\u2013187.\n                  <\/jats:p>","DOI":"10.1556\/650.2026.33484","type":"journal-article","created":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T09:05:38Z","timestamp":1769936738000},"page":"180-187","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Mozg\u00e1sszervi eredet\u0171 mellkasi f\u00e1jdalmat felismer\u0151 klinikai predikci\u00f3s modell fejleszt\u00e9se"],"prefix":"10.1556","volume":"167","author":[{"given":"Korn\u00e9l","family":"\u00c1d\u00e1m","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, S\u00fcrg\u0151ss\u00e9gi Orvostani Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Varga","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, S\u00fcrg\u0151ss\u00e9gi Orvostani Klinika Budapest Magyarorsz\u00e1g"},{"name":"Somogy V\u00e1rmegyei Kaposi M\u00f3r Oktat\u00f3 K\u00f3rh\u00e1z Kaposv\u00e1r Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Eg\u00e9szs\u00e9gtudom\u00e1nyi Kar, S\u00fcrg\u0151ss\u00e9gi, Eg\u00e9szs\u00e9gpedag\u00f3giai \u00e9s \u00c1pol\u00e1studom\u00e1nyi Int\u00e9zet P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1nk G.","family":"Fenyves","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, S\u00fcrg\u0151ss\u00e9gi Orvostani Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina","family":"Hegyi","sequence":"additional","affiliation":[{"name":"Taksony 1. sz. feln\u0151tt h\u00e1ziorvosi k\u00f6rzet Taksony Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"Kosty\u00e1l","sequence":"additional","affiliation":[{"name":"Borsod-Aba\u00faj-Zempl\u00e9n V\u00e1rmegyei K\u00f6zponti K\u00f3rh\u00e1z \u00e9s Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Miskolc Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ervin","family":"Finta","sequence":"additional","affiliation":[{"name":"D\u00e9l-budai Centrumk\u00f3rh\u00e1z \u2013 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Kanizsai","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, S\u00fcrg\u0151ss\u00e9gi Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6454-6078","authenticated-orcid":true,"given":"Zsuzsanna","family":"Lelovics","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Orvosi N\u00e9peg\u00e9szs\u00e9gtani Int\u00e9zet P\u00e9cs, Szigeti \u00fat 12., 7624 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Xantus","sequence":"additional","affiliation":[{"name":"D\u00e9l-budai Centrumk\u00f3rh\u00e1z \u2013 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Csal\u00e1dorvosi Tansz\u00e9k Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Body R, Carlton E. Understanding cardiac troponin. Part 1: Avoiding\n                    troponinitis. Emerg Med J. 2018; 35: 120-125.\n                        https:\/\/doi.org\/10.1136\/emermed-2017-206812","DOI":"10.1136\/emermed-2017-206812"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Kupovits TR. Symptoms and options in rehabilit\u00e1ltidon of\n                    post-COVID-19 syndrome (long-COVID). [A poszt-COVID-19-szindr\u00f3ma (long-COVID)\n                    t\u00fcnetei \u00e9s a rehabilit\u00e1ci\u00f3 lehet\u0151s\u00e9gei.] Orv Hetil. 2024; 165: 1266-1274.\n                    [Hungarian] https:\/\/doi.org\/10.1556\/650.2024.33107","DOI":"10.1556\/650.2024.33107"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Pir\u00f3th Zs, Csan\u00e1di B, Bora N, et el. Coronary microvascular disease,\n                    vasospastic angina. [Microvascularis coronariabetegs\u00e9g, vasospasticus angina.]\n                    Orv Hetil. 2024; 165: 1613-1620. [Hungarian]\n                        https:\/\/doi.org\/10.1556\/650.2024.33131","DOI":"10.1556\/650.2024.33131"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Sayyad MH, Levi N, Bruoha S, et el. Defensive medicine in an\n                    emergency department: the overuse of high-sensitivity cardiac troponin I\n                    testing. Life (Basel) 2024; 14: 1563.\n                        https:\/\/doi.org\/10.3390\/life14121563","DOI":"10.3390\/life14121563"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Haasenritter J, Biroga T, Keunecke C, et al. Causes of chest pain in\n                    primary care - a systematic review and meta-analysis. Croat Med J. 2015; 56:\n                    422-430. https:\/\/doi.org\/10.3325\/cmj.2015.56.422","DOI":"10.3325\/cmj.2015.56.422"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Luli J, Scheidemantel A, Bennett K, et al. A retrospective\n                    validation of HEAR score. JACC Case Rep. 2024; 29: 102794.\n                        https:\/\/doi.org\/10.1016\/j.jaccas.2024.102794","DOI":"10.1016\/j.jaccas.2024.102794"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC guidelines\n                    for the diagnosis and management of acute pulmonary embolism developed in\n                    collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020;\n                    41: 543-603.\n                    https:\/\/doi.org\/10.1093\/eurheartj\/ehz405","DOI":"10.1093\/eurheartj\/ehz405"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Keskin HV, Ozcelik N, Senturk Topaloglu E, et al. Which is more\n                    valuable in the diagnosis of pulmonary thromboembolism? The Wells score, the\n                    Revised Geneva score, or the Padua score? Life (Basel) 2025; 15: 1115.\n                        https:\/\/doi.org\/10.3390\/life15071115","DOI":"10.3390\/life15071115"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Xantus G, Burke D, Kanizsai P. Previously undiagnosed scoliosis\n                    presenting as pleuritic chest pain in the emergency department - a case series\n                    and a validating retrospective audit. BMC Emerg Med. 2021; 21: 62.\n                        https:\/\/doi.org\/10.1186\/s12873-021-00455-x","DOI":"10.1186\/s12873-021-00455-x"},{"key":"R10","unstructured":"Rao SV, O\u2019Donoghue ML, Ruel M, et al. 2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI\n                    Guideline for the management of patients with acute coronary syndromes: A report\n                    of the American College of Cardiology\/American Heart Association Joint Committee\n                    on Clinical Practice Guidelines. Circulation 2025; 151: e771-e862. Erratum:\n                    Circulation 2025; 151: e865. Erratum: Circulation 2025; 151: e1098. Erratum:\n                    Circulation 2025; 152: e402."},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for\n                    the management of acute coronary syndromes. Eur Heart J. 2023; 44: 3720-3826.\n                        https:\/\/doi.org\/10.1093\/eurheartj\/ehad191","DOI":"10.1093\/eurheartj\/ehad191"},{"key":"R12","doi-asserted-by":"crossref","unstructured":"Jany B, Welte T. Pleural effusion in adults - etiology, diagnosis,\n                    and treatment. Dtsch \u00c4rztebl Int. 2019; 116: 377-386.\n                        https:\/\/doi.org\/10.3238\/arztebl.2019.0377","DOI":"10.3238\/arztebl.2019.0377"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Xantus G, Peczel\u00e1k P, Hegyi K, et al. Bedside ultrasound in adult\n                    primary care. [\u00c1gy melletti ultrahangvizsg\u00e1lat az alapell\u00e1t\u00e1sban.] Orv Hetil.\n                    2022; 163: 2067-2071. [Hungarian]\n                        https:\/\/doi.org\/10.1556\/650.2022.32683","DOI":"10.1556\/650.2022.32683"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"Peduzzi P, Concato J, Kemper E, et al. A simulation study of the\n                    number of events per variable in logistic regression analysis. J Clin Epidemiol.\n                    1996; 49: 1373-1379.\n                    https:\/\/doi.org\/10.1016\/S0895-4356(96)00236-3","DOI":"10.1016\/S0895-4356(96)00236-3"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Riley RD, Ensor J, Snell KI, et al. Calculating the sample size\n                    required for developing a clinical prediction model. BMJ 2020; 368: m441.\n                        https:\/\/doi.org\/10.1136\/bmj.m441","DOI":"10.1136\/bmj.m441"},{"key":"R16","unstructured":"Zhang Z. Multiple imputation with multivariate imputation by chained\n                    equation (MICE) package. Ann Transl Med. 2016; 4: 30."},{"key":"R17","doi-asserted-by":"crossref","unstructured":"Collins GS, Moons KG, Dhiman P, et al. TRIPOD+AI statement: updated\n                    guidance for reporting clinical prediction models that use regression or machine\n                    learning methods. BMJ 2024; 385: e078378. Erratum: BMJ 2024; 385: q902.\n                        https:\/\/doi.org\/10.1136\/bmj.q902","DOI":"10.1136\/bmj.q902"}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/www.akjournals.com\/view\/journals\/650\/167\/5\/article-p180.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akjournals.com\/downloadpdf\/journals\/650\/167\/5\/article-p180.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.akjournals.com\/downloadpdf\/journals\/650\/167\/5\/article-p180.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:32:11Z","timestamp":1785508331000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akjournals.com\/view\/journals\/650\/167\/5\/article-p180.xml"}},"subtitle":["Prospekt\u00edv pilotvizsg\u00e1lati elk\u00e9pzel\u00e9s"],"short-title":[],"issued":{"date-parts":[[2026,2,1]]},"references-count":17,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1556\/650.2026.33484","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,1]]}}}