{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T13:11:39Z","timestamp":1785503499161,"version":"3.56.0"},"reference-count":48,"publisher":"Akademiai Kiado Zrt.","issue":"17","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,4,26]]},"abstract":"<jats:p>A szerz\u0151k \u00e1ttekint\u00e9st adnak a fizioter\u00e1pi\u00e1s kezel\u00e9sek immunv\u00e1laszt befoly\u00e1sol\u00f3\n                    hat\u00e1sair\u00f3l. A fizioter\u00e1pia f\u00e1jdalomcsillap\u00edt\u00f3 \u00e9s gyullad\u00e1scs\u00f6kkent\u0151\n                    mechanizmus\u00e1ban d\u00f6nt\u0151 szerepet j\u00e1tszik az immunmodul\u00e1ci\u00f3. A v\u00e1zizomzat\n                    szekr\u00e9ci\u00f3s szerv, amely mozg\u00e1s hat\u00e1s\u00e1ra miokineket v\u00e1laszt ki. Az egyik\n                    legismertebb ezek k\u00f6z\u00fcl az irizin, amely fontos szerepet j\u00e1tszik az oxidat\u00edv\n                    stressz g\u00e1tl\u00e1s\u00e1ban, a sziszt\u00e9m\u00e1s gyullad\u00e1sos reakci\u00f3k cs\u00f6kkent\u00e9s\u00e9ben \u00e9s a\n                    neuroprotekci\u00f3ban, emellett pozit\u00edv hat\u00e1st gyakorol a szab\u00e1lyoz\u00f3 T-sejtek\n                    funkci\u00f3ira, modul\u00e1lja az immunsejteket, n\u00f6veli a gyullad\u00e1scs\u00f6kkent\u0151 citokinek\n                    termel\u00e9s\u00e9t. A legfontosabb fizioter\u00e1pi\u00e1s kezel\u00e9s a gy\u00f3gytorna, amelyr\u0151l a\n                    legt\u00f6bb bizony\u00edt\u00e9k \u00e1ll rendelkez\u00e9s\u00fcnkre. A gy\u00f3gytorna jelent\u0151s szerepet j\u00e1tszik\n                    az autoimmun betegs\u00e9gek klinikai \u00e1llapot\u00e1nak jav\u00edt\u00e1s\u00e1ban. A rendszeres fizikai\n                    aktivit\u00e1s kedvez\u0151 tumorimmunol\u00f3giai hat\u00e1sokkal b\u00edr, amelyek nem j\u00e1rnak k\u00e1ros\n                    mell\u00e9khat\u00e1sokkal. Emellett a gy\u00f3gytorna fokozza a daganatellenes immunv\u00e1laszban\n                    kulcsszerepet bet\u00f6lt\u0151 term\u00e9szetes \u00f6l\u0151sejtek sz\u00e1m\u00e1t. A massz\u00e1zs, valamint sz\u00e1mos\n                    elektroter\u00e1pi\u00e1s \u00e9s fotobiomodul\u00e1ci\u00f3s kezel\u00e9s is befoly\u00e1solja az immunv\u00e1laszt.\n                    Radon- \u00e9s k\u00e9nes f\u00fcrd\u0151k\u00far\u00e1kat k\u00f6vet\u0151en a citokinszintek \u00e9s egy\u00e9b gyullad\u00e1sos\n                    biomarkerek statisztikailag szignifik\u00e1ns cs\u00f6kken\u00e9s\u00e9t \u00edrt\u00e1k le. A\n                    teljestest-krioter\u00e1pia gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1sa feltehet\u0151en az interleukin-6 \u00e9s\n                    a tumornekr\u00f3zisfaktor-alfa szintj\u00e9nek m\u00e9rs\u00e9kl\u0151d\u00e9s\u00e9n kereszt\u00fcl \u00e9rv\u00e9nyes\u00fcl. A\n                    fizioter\u00e1pi\u00e1s kezel\u00e9sek immunv\u00e1laszra gyakorolt hat\u00e1sainak ismerete fontos a\n                    gyullad\u00e1sos betegs\u00e9gek kezel\u00e9si srat\u00e9gi\u00e1j\u00e1nak megv\u00e1laszt\u00e1sakor. Orv Hetil. 2026;\n                    176(17): 651\u2013660.<\/jats:p>","DOI":"10.1556\/650.2026.33525","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:28:37Z","timestamp":1777688917000},"page":"651-660","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["A fizioter\u00e1pi\u00e1s kezel\u00e9sek hat\u00e1sa az immunrendszerre"],"prefix":"10.1556","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1170-3767","authenticated-orcid":true,"given":"Tam\u00e1s","family":"Bender","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Reumatol\u00f3giai \u00e9s Immunol\u00f3giai Klinika Budapest, Frankel Le\u00f3 \u00fat 25\u201329., 1023 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u00f6rgy","family":"Nagy","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Reumatol\u00f3giai \u00e9s Immunol\u00f3giai Klinika Budapest, Frankel Le\u00f3 \u00fat 25\u201329., 1023 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Ong KL, Santomauro DF, Bhoomadevi A, et al. 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