{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:04:06Z","timestamp":1785506646230,"version":"3.56.0"},"reference-count":40,"publisher":"Akademiai Kiado Zrt.","issue":"20","license":[{"start":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T00:00:00Z","timestamp":1778976000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"HUNREN-ONKOL-TTK-HCEMM Onkogenomikai Kutat\u00f3csoport"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,5,17]]},"abstract":"<jats:p>A testicularis sex cord-stroma tumorok a here sex cord (ivarl\u00e9c) \u00e9s stroma\n                    elemeib\u0151l kiindul\u00f3, ritka, biol\u00f3giailag igen heterog\u00e9n viselked\u00e9st mutat\u00f3\n                    daganatok. Hab\u00e1r 90%-ban klinikailag indolens laesi\u00f3kr\u00f3l besz\u00e9lhet\u00fcnk, a\n                    fennmarad\u00f3 esetekben agressz\u00edv, ter\u00e1piarezisztens k\u00f3rlefoly\u00e1s jellemzi \u0151ket, ami\n                    hamar a betegek \u00e9let\u00e9be ker\u00fclhet. Emellett sz\u00f6vetileg t\u00f6bb esetben diagnosztikus\n                    neh\u00e9zs\u00e9get okozhat a cs\u00edrasejtes daganatokt\u00f3l val\u00f3 elk\u00fcl\u00f6n\u00edt\u00e9s\u00fck. A szerz\u0151k\n                    bemutatj\u00e1k a k\u00f6vetkez\u0151 entit\u00e1sok klinikopatol\u00f3giai jellegzetess\u00e9geit:\n                    Leydig-sejtes tumor, Sertoli-sejtes tumor k\u00fcl\u00f6n megnevez\u00e9s n\u00e9lk\u00fcl, nagysejtes\n                    kalcifik\u00e1l\u00f3 Sertoli-sejtes tumor, feln\u0151tt t\u00edpus\u00fa granulosasejtes tumor,\n                    juvenilis t\u00edpus\u00fa granulosasejtes tumor, fibroma\/thecoma csoport, kevert sex\n                    cord-stromalis tumor, pecs\u00e9tgy\u0171r\u0171sejtes stromalis tumor, myoid gonadalis\n                    stromalis tumor, sex cord-stromalis tumor k\u00fcl\u00f6n megnevez\u00e9s n\u00e9lk\u00fcl. A k\u00f6zlem\u00e9ny\n                    c\u00e9lja a hazai orvosk\u00f6z\u00f6ss\u00e9g tagjaival megismertetni ezeket az elt\u00e9r\u00e9seket,\n                    el\u0151mozd\u00edtva ezzel a felismer\u00e9s\u00fcket, megfelel\u0151 ell\u00e1t\u00e1sukat \u00e9s az esetek gy\u0171jt\u00e9s\u00e9t\n                    k\u00fcl\u00f6nb\u00f6z\u0151 c\u00e9lzott vizsg\u00e1latok elv\u00e9gz\u00e9s\u00e9hez. Orv Hetil. 2026; 167(20):\n                    784\u2013797.<\/jats:p>","DOI":"10.1556\/650.2026.33550","type":"journal-article","created":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T14:35:10Z","timestamp":1779028510000},"page":"784-797","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Testicularis sex cord-stroma daganatok"],"prefix":"10.1556","volume":"167","author":[{"given":"M\u00e1rton Csaba","family":"Gr\u00e1czia","sequence":"first","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest, R\u00e1th Gy. u. 7\u20139., 1122 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina","family":"B\u00edr\u00f3","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Kemoter\u00e1pia \u201eC\u201d \u00e9s Klinikai Farmakol\u00f3giai Oszt\u00e1ly Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogl\u00e1rka","family":"P\u00f3sfai","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e1vid","family":"Semj\u00e9n","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00e9s Klinikai K\u00f6zpont, Pathologiai Int\u00e9zet P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsombor","family":"Melegh","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest, R\u00e1th Gy. u. 7\u20139., 1122 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Fejes","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Radiol\u00f3giai Klinika Szeged Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Sz\u00e9kely","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai, Igazs\u00e1g\u00fcgyi \u00e9s Biztos\u00edt\u00e1si Orvostani Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Jakab","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai, Igazs\u00e1g\u00fcgyi \u00e9s Biztos\u00edt\u00e1si Orvostani Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Jenei","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9247-6679","authenticated-orcid":true,"given":"Levente","family":"Kuthi","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest, R\u00e1th Gy. u. 7\u20139., 1122 Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"},{"name":"HUN-REN-ONKOL-TTK-HCEMM Onkogenomikai Kutat\u00f3csoport Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Acosta AM, Idrees MT, Berney DM, et al. 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Ann Diagn Pathol. 2018; 35: 42-47.\n                        https:\/\/doi.org\/10.1016\/j.anndiagpath.2018.04.003","DOI":"10.1016\/j.anndiagpath.2018.04.003"},{"key":"R39","doi-asserted-by":"crossref","unstructured":"Kao CS, Ulbright TM. A morphologic and immunohistochemical\n                    comparison of nuclear \u03b2-catenin expressing testicular Sertoli cell tumors and\n                    pancreatic solid pseudopapillary neoplasms supporting their continued separate\n                    classification. Am J Surg Pathol. 2020; 44: 1082-1091.\n                        https:\/\/doi.org\/10.1097\/PAS.0000000000001527","DOI":"10.1097\/PAS.0000000000001527"},{"key":"R40","doi-asserted-by":"crossref","unstructured":"Acosta AM, Colecchia M, Comperat E, et al. 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