{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T04:30:09Z","timestamp":1786681809981,"version":"build-2736575974"},"reference-count":50,"publisher":"Akademiai Kiado Zrt.","issue":"27","license":[{"start":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:00:00Z","timestamp":1783209600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,7,5]]},"abstract":"<jats:p>Az akut COVID\u201319 lezajl\u00e1s\u00e1t k\u00f6vet\u0151en post-COVID-, avagy long-COVID-szindr\u00f3ma\n                    l\u00e9phet fel, mely a fert\u0151z\u00e9s akut id\u0151szaka ut\u00e1n is fenn\u00e1ll\u00f3 kellemetlen\n                    perziszt\u00e1l\u00f3 vagy \u00faj kelet\u0171 t\u00fcnetekkel jellemezhet\u0151, az \u00e9rintett betegek\n                    \u00e9letmin\u0151s\u00e9g\u00e9t ronthatja, \u00e9s egyn\u00e9l t\u00f6bb szervrendszert is \u00e9rinthet. Az \u00e1llapot\n                    sokszor diagnosztikus \u00e9s f\u0151k\u00e9nt ter\u00e1pi\u00e1s kih\u00edv\u00e1st jelenthet az\n                    ell\u00e1t\u00f3rendszernek, pontos lefoly\u00e1sa \u00e9s kimenetelei egyel\u0151re nem ismertek teljes\n                    m\u00e9rt\u00e9kben. A diagnosztikus megk\u00f6zel\u00edt\u00e9s multidiszciplin\u00e1ris szeml\u00e9letet ig\u00e9nyel,\n                    amelyben kiemelt szerepet kapnak a k\u00e9palkot\u00f3 vizsg\u00e1latok (p\u00e9ld\u00e1ul mellkasi CT),\n                    a funkcion\u00e1lis \u00e1llapotot felm\u00e9r\u0151 vizsg\u00e1latok (6 perces j\u00e1r\u00e1steszt,\n                    l\u00e9gz\u00e9sfunkci\u00f3, cardiopulmonalis terhel\u00e9ses teszt), valamint a betegek \u00e1ltal\n                    szubjekt\u00edven jelzett param\u00e9terek (t\u00fcneti profil, \u00e9letmin\u0151s\u00e9g) felm\u00e9r\u00e9se is. A\n                    long-COVID-\u00e1llapot r\u00e9szek\u00e9nt bizonyos esetekben a v\u00edrusinfekci\u00f3\n                    k\u00f6vetkezm\u00e9nyek\u00e9nt a t\u00fcd\u0151parenchyma kiterjedt k\u00e1rosod\u00e1sa detekt\u00e1lhat\u00f3 k\u00e9palkot\u00f3\n                    felv\u00e9teleken, melyet a szakirodalom post-COVID-t\u00fcd\u0151fibrosisk\u00e9nt eml\u00edt. A\n                    ter\u00e1pi\u00e1s lehet\u0151s\u00e9gek jelenleg korl\u00e1tozottak, \u00e9s nagyr\u00e9szt t\u00fcneti, illetve\n                    szervspecifikus megk\u00f6zel\u00edt\u00e9sen alapulnak, ugyanakkor az akut f\u00e1zisban\n                    alkalmazott antivir\u00e1lis kezel\u00e9sek, mint a remdesivir vagy a\n                    nirmatrelvir\/ritonavir, potenci\u00e1lisan befoly\u00e1solhatj\u00e1k a k\u00e9s\u0151i sz\u00f6v\u0151dm\u00e9nyek\n                    kialakul\u00e1s\u00e1t. A megel\u0151z\u00e9s kulcsszerepet j\u00e1tszik, k\u00fcl\u00f6n\u00f6s tekintettel a\n                    vakcin\u00e1ci\u00f3ra, amely bizony\u00edtottan cs\u00f6kkenti a s\u00falyos betegs\u00e9g \u00e9s feltehet\u0151en a\n                    long-COVID kialakul\u00e1s\u00e1nak kock\u00e1zat\u00e1t is. A long-COVID-szindr\u00f3ma \u00e9s a\n                    post-COVID-t\u00fcd\u0151fibrosis patomechanizmus\u00e1nak pontosabb meg\u00e9rt\u00e9s\u00e9hez tov\u00e1bbi\n                    hossz\u00fa t\u00e1v\u00fa betegk\u00f6vet\u00e9s lehet sz\u00fcks\u00e9ges. A jelen k\u00f6zlem\u00e9ny c\u00e9lja a\n                    long-COVID-szindr\u00f3ma \u00e9s a post-COVID-t\u00fcd\u0151fibrosis bemutat\u00e1sa egy naprak\u00e9sz,\n                    \u00e1tfog\u00f3 \u00f6sszefoglal\u00f3 form\u00e1j\u00e1ban. Orv Hetil. 2026; 167(27): 1051\u2013158.<\/jats:p>","DOI":"10.1556\/650.2026.33584","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T12:43:32Z","timestamp":1783341812000},"page":"1051-1058","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Long-COVID-szindr\u00f3ma \u00e9s COVID\u201319-et k\u00f6vet\u0151 t\u00fcd\u0151specifikus elt\u00e9r\u00e9sek"],"prefix":"10.1556","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0428-703X","authenticated-orcid":true,"given":"Dorottya","family":"F\u00e9s\u00fc","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika Budapest, T\u00f6m\u0151 u. 25\u201329., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika Budapest, T\u00f6m\u0151 u. 25\u201329., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika Budapest, T\u00f6m\u0151 u. 25\u201329., 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Al-Aly Z, Davis H, McCorkell L, et al. 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