{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:06:48Z","timestamp":1789531608242,"version":"build-2803163510"},"reference-count":30,"publisher":"Akademiai Kiado Zrt.","issue":"37","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,9,13]]},"abstract":"\n Bevezet\u00e9s:<\/jats:italic>\n A pajzsmirigyr\u00e1kok incidenci\u00e1ja vil\u00e1gszerte\n jelent\u0151sen emelkedett az elm\u00falt k\u00e9t \u00e9vtizedben, mik\u00f6zben a hal\u00e1loz\u00e1s nem\n v\u00e1ltozott. A korai felismer\u00e9s \u00e9s a korszer\u0171 kezel\u00e9si protokollok\n kulcsfontoss\u00e1g\u00faak a betegek t\u00fal\u00e9l\u00e9s\u00e9nek \u00e9s \u00e9letmin\u0151s\u00e9g\u00e9nek jav\u00edt\u00e1s\u00e1ban.\n C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n Vizsg\u00e1latunk els\u0151dleges c\u00e9lja a differenci\u00e1lt\n pajzsmirigyr\u00e1k hazai diagnosztikus \u00e9s ter\u00e1pi\u00e1s gyakorlat\u00e1nak felt\u00e9rk\u00e9pez\u00e9se\n volt.\n M\u00f3dszer:<\/jats:italic>\n Retrospekt\u00edv vizsg\u00e1latunk a 2011 \u00e9s 2024 k\u00f6z\u00f6tti\n id\u0151szakban pajzsmirigyr\u00e1kkal diagnosztiz\u00e1lt betegek klinikai adataira f\u00f3kusz\u00e1lt.\n A vizsg\u00e1lat sor\u00e1n nem volt kiz\u00e1r\u00e1si krit\u00e9rium, \u00edgy a popul\u00e1ci\u00f3 reprezentat\u00edv\n k\u00e9pet adott a hazai gyakorlatr\u00f3l.\n Eredm\u00e9nyek:<\/jats:italic>\n \u00d6sszesen 893\n beteg (75,7% n\u0151, 24,3% f\u00e9rfi) adatait elemezt\u00fck. A vizsg\u00e1lt popul\u00e1ci\u00f3\n \u00e1tlag\u00e9letkora 53,1 \u00b1 14,8 \u00e9v volt. A differenci\u00e1lt pajzsmirigyr\u00e1kok\n dominanci\u00e1ja, ezen bel\u00fcl a papillaris forma ar\u00e1nya (82,8%) kiemelked\u0151 volt. A\n betegek 63,5%-\u00e1t korai st\u00e1diumban (T1a\u2013T1b) diagnosztiz\u00e1lt\u00e1k, a region\u00e1lis\n nyirokcsom\u00f3k \u00e9rintetts\u00e9ge 34%-ban, t\u00e1voli \u00e1tt\u00e9t 4,7%-ban fordult el\u0151. A legt\u00f6bb\n beteg egy m\u0171t\u00e9ten esett \u00e1t, t\u00f6bbs\u00e9g\u00fckn\u00e9l (80,8%) tot\u00e1lis vagy k\u00f6zel tot\u00e1lis\n thyreoidectomi\u00e1t v\u00e9geztek. A region\u00e1lis nyirokcsom\u00f3k \u00e9rintetts\u00e9g\u00e9t c\u00e9lz\u00f3\n beavatkoz\u00e1sok gyakoriak voltak, m\u00edg a radik\u00e1lis nyaki dissectio ritk\u00e1bbnak\n bizonyult, ami \u00f6sszhangban van a differenci\u00e1lt pajzsmirigyr\u00e1k tipikus\n lokoregion\u00e1lis terjed\u00e9s\u00e9vel \u00e9s a modern, c\u00e9lzott seb\u00e9szi strat\u00e9gi\u00e1val. A\n radioj\u00f3d-ter\u00e1pi\u00e1ban r\u00e9szes\u00fcl\u0151 betegek \u00e1tlagosan 1,41 alkalommal kaptak kezel\u00e9st.\n A radioj\u00f3dd\u00f3zisok jelent\u0151s variabilit\u00e1st mutattak, az \u00e1tlagos d\u00f3zis 2645 MBq\n volt, m\u00edg az alkalmazott kumulat\u00edv d\u00f3zisok sz\u00e9ls\u0151\u00e9rt\u00e9kei 1100 MBq-t\u0151l eg\u00e9szen\n 11\u00a0000 MBq-ig terjedtek. TSH-szuppresszi\u00f3s kezel\u00e9st a betegek 57,7%-\u00e1ban,\n sziszt\u00e9m\u00e1s ter\u00e1pi\u00e1t 3,2%-\u00e1ban alkalmaztak.\n Megbesz\u00e9l\u00e9s:<\/jats:italic>\n A\n vizsg\u00e1lat eredm\u00e9nyei azt mutatj\u00e1k, hogy a magyarorsz\u00e1gi pajzsmirigyr\u00e1kos betegek\n ell\u00e1t\u00e1s\u00e1ban a diagnosztikus \u00e9s ter\u00e1pi\u00e1s gyakorlat a nemzetk\u00f6zi standardoknak\n megfelel\u0151.\n K\u00f6vetkeztet\u00e9s:<\/jats:italic>\n A vizsg\u00e1lat \u00e1tfog\u00f3 k\u00e9pet adott a\n pajzsmirigyr\u00e1kban szenved\u0151 hazai betegek demogr\u00e1fiai, sz\u00f6vettani \u00e9s kezel\u00e9si\n saj\u00e1toss\u00e1gair\u00f3l, hozz\u00e1j\u00e1rulva a klinikai gyakorlat \u00e9rt\u00e9kel\u00e9s\u00e9hez. Az eredm\u00e9nyek\n tov\u00e1bbi klinikai kutat\u00e1sok \u00e9s ut\u00e1nk\u00f6vet\u00e9ses elemz\u00e9sek alapj\u00e1ul szolg\u00e1lhatnak,\n el\u0151seg\u00edtve a pajzsmirigyr\u00e1k kezel\u00e9s\u00e9nek hossz\u00fa t\u00e1v\u00fa optimaliz\u00e1l\u00e1s\u00e1t \u00e9s a betegek\n progn\u00f3zis\u00e1nak jav\u00edt\u00e1s\u00e1t. Orv Hetil. 2026; 167(37): 1468\u20131476.\n <\/jats:p>","DOI":"10.1556\/650.2026.33649","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:24:04Z","timestamp":1789529044000},"page":"1468-1476","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["A pajzsmirigyr\u00e1k val\u00f3s \u00e9letbeli, retrospekt\u00edv vizsg\u00e1lata a hazai gyakorlat felt\u00e9rk\u00e9pez\u00e9s\u00e9re"],"prefix":"10.1556","volume":"167","author":[{"given":"Annam\u00e1ria","family":"Erdei","sequence":"first","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati Int\u00e9zet, Endokrinol\u00f3giai Tansz\u00e9k Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Blasszauer","sequence":"additional","affiliation":[{"name":"MedicalScan Kft. Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"Komka","sequence":"additional","affiliation":[{"name":"MedicalScan Kft. Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mi","family":"Szkib\u00e1k","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati Int\u00e9zet, Endokrinol\u00f3giai Tansz\u00e9k Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Endre","family":"Nagy","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati Int\u00e9zet, Endokrinol\u00f3giai Tansz\u00e9k Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Berta","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati Int\u00e9zet, Endokrinol\u00f3giai Tansz\u00e9k Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Nagy","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, II. 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Incidence and mortality of thyroid\n cancer in 50 countries: a joinpoint regression analysis of global trends.\n Endocrine 2023; 80: 355-365.\n https:\/\/doi.org\/10.1007\/s12020-022-03274-7","DOI":"10.1007\/s12020-022-03274-7"},{"key":"R4","unstructured":"Hungarian National Cancer Register. [Nemzeti R\u00e1kregiszter.] 2023.\n Available from: stat.nrr.hu [accessed: May 25, 2026]."},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Szuj\u00f3 S, Bajnok L, B\u00f3dis B, et al. Recovery rate in differentiated\n thyroid cancer. Experiences of one of the Hungarian clinical centers. [A\n differenci\u00e1lt pajzsmirigyr\u00e1kban szenved\u0151 betegek gy\u00f3gyul\u00e1si es\u00e9lyei. Egy hazai\n centrum tapasztalatai.] Orv Hetil. 2018; 159: 878-884. [Hungarian]\n https:\/\/doi.org\/10.1556\/650.2018.31060","DOI":"10.1556\/650.2018.31060"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Asa SL. The current histologic classification of thyroid cancer.\n Endocrinol Metab Clin North Am. 2019; 48: 1-22.\n https:\/\/doi.org\/10.1016\/j.ecl.2018.10.001","DOI":"10.1016\/j.ecl.2018.10.001"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Li YD, Ye QY, Chen YX, et al. Thyroid cancer: pathogenesis,\n clinicopathology, diagnosis, and management. MedComm (2020) 2025; 6: e70449.\n https:\/\/doi.org\/10.1002\/mco2.70449","DOI":"10.1002\/mco2.70449"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Smallridge RC, Copland JA. Anaplastic thyroid carcinoma:\n pathogenesis and emerging therapies. Clin Oncol. (R Coll Radiol.) 2010; 22:\n 486-497. https:\/\/doi.org\/10.1016\/j.clon.2010.03.013","DOI":"10.1016\/j.clon.2010.03.013"},{"key":"R9","unstructured":"Lin B, Ma H, Ma M, et al. The incidence and survival analysis for\n anaplastic thyroid cancer: a SEER database analysis. 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