{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:51:46Z","timestamp":1791193906257,"version":"4.1.0"},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"40","content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2026,10,4]]},"abstract":"<jats:p>A plasztikai seb\u00e9szet modern kori fejl\u0151d\u00e9se \u00faj m\u0171t\u00e9ttechnikai lehet\u0151s\u00e9geket adott\n                    a testk\u00e9p \u00e9s az \u00f6n\u00e9rt\u00e9kel\u00e9s pozit\u00edv megv\u00e1ltoztat\u00e1s\u00e1hoz, jav\u00edt\u00e1s\u00e1hoz. A\n                    plasztikai seb\u00e9szeti implant\u00e1tumok alkalmaz\u00e1sa \u00e9vtizedek \u00f3ta a rekonstrukci\u00f3s \u00e9s\n                    eszt\u00e9tikai seb\u00e9szet alapvet\u0151 eszk\u00f6ze. Ezzel p\u00e1rhuzamosan az ut\u00f3bbi k\u00e9t\n                    \u00e9vtizedben a tudom\u00e1nyos orvosi szakirodalom mellett a k\u00f6zbesz\u00e9dben, a sajt\u00f3ban\n                    \u00e9s a bulv\u00e1rm\u00e9di\u00e1ban is egyre nagyobb teret nyert az implant\u00e1tummal \u00f6sszef\u00fcgg\u00e9sbe\n                    hozott k\u00f3rk\u00e9pek k\u00f6z\u00fcl az eml\u0151implant\u00e1tum-betegs\u00e9g (breast implant illness \u2013\n                    BII), az eml\u0151implant\u00e1tummal \u00f6sszef\u00fcgg\u0151 anaplasticus nagysejtes lymphoma (breast\n                    implant-associated anaplastic large cell lymphoma \u2013 BIA-ALCL) \u00e9s az\n                    eml\u0151implant\u00e1tummal \u00f6sszef\u00fcgg\u0151 laph\u00e1mr\u00e1k (breast implant-associated squamous cell\n                    carcinoma \u2013 BIA-SCC) probl\u00e9mak\u00f6re. Emiatt ezek a klinikai k\u00f3rk\u00e9pek nem csup\u00e1n\n                    orvosi, hanem pszichol\u00f3giai, etikai \u00e9s t\u00e1rsadalmi dilemm\u00e1kat is felvethetnek. A\n                    jelen k\u00f6zlem\u00e9nyben bemutat\u00e1sra ker\u00fcl\u0151 eml\u0151implant\u00e1tum-betegs\u00e9g nem egys\u00e9gesen\n                    defini\u00e1lt, vitatott, de klinikailag relev\u00e1ns szindr\u00f3ma. A heterog\u00e9n\n                    t\u00fcnetegy\u00fcttesben a betegek k\u00fcl\u00f6nb\u00f6z\u0151 sziszt\u00e9m\u00e1s panaszokat (p\u00e9ld\u00e1ul kr\u00f3nikus\n                    f\u00e1radts\u00e1g, \u00edz\u00fcleti- \u00e9s izomf\u00e1jdalmak, hangulatzavarok, hajhull\u00e1s stb.)\n                    t\u00e1rs\u00edtanak mellimplant\u00e1tumaikhoz an\u00e9lk\u00fcl, hogy egy\u00e9rtelm\u0171 \u00f6sszef\u00fcgg\u00e9s\n                    kimutathat\u00f3 lenne, vagy objekt\u00edven detekt\u00e1lhat\u00f3 klinikai param\u00e9terrel\n                    rendelkezn\u00e9nek. Eml\u0151implant\u00e1tum-betegs\u00e9g t\u00fcnetei eset\u00e9n megfelel\u0151 diagnosztikai\n                    \u00e9s differenci\u00e1ldiagnosztikai eredm\u00e9nyek \u00e9s indik\u00e1ci\u00f3s t\u00e9nyez\u0151k birtok\u00e1ban\n                    jelenleg az egyik els\u0151 \u00e9s legfontosabb kezel\u00e9si strat\u00e9gia a teljes\n                    implant\u00e1tumnak \u00e9s a k\u00f6r\u00fcl\u00f6tte k\u00e9pz\u0151d\u00f6tt k\u00f6t\u0151sz\u00f6vetes toknak az elt\u00e1vol\u00edt\u00e1sa\n                    (explant\u00e1ci\u00f3 + teljes capsulectomia). A p\u00e1ciensek mintegy 60\u201380%-a sz\u00e1mol be a\n                    t\u00fcnetek r\u00e9szleges vagy teljes megsz\u0171n\u00e9s\u00e9r\u0151l a m\u0171t\u00e9t ut\u00e1n. Az\n                    eml\u0151implant\u00e1tum-betegs\u00e9ghez k\u00f6thet\u0151 immunol\u00f3giai \u00e9s patol\u00f3giai folyamatokat,\n                    epidemiol\u00f3giai \u00e9s klinikai aspektusait bemutat\u00f3 jelen \u00f6sszefoglal\u00f3 k\u00f6zlem\u00e9ny \u2013 a\n                    nemzetk\u00f6zi szakirodalom \u00e9s aj\u00e1nl\u00e1sok t\u00fckr\u00e9ben \u2013 javaslatokat tesz a seb\u00e9szeti\n                    gyakorlat \u00e9s a kommunik\u00e1ci\u00f3s strat\u00e9gia korszer\u0171s\u00edt\u00e9s\u00e9re. Orv Hetil. 2026;\n                    167(40): 1593\u20131604.<\/jats:p>","DOI":"10.1556\/650.2026.33680","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:58:52Z","timestamp":1791190732000},"page":"1593-1604","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Az eml\u0151implant\u00e1tum-betegs\u00e9gek Janus-arca I."],"prefix":"10.1556","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8564-2726","authenticated-orcid":true,"given":"B\u00e9la Zolt\u00e1n","family":"Debreczeni","sequence":"first","affiliation":[{"name":"DrD Plasztikai St\u00fadi\u00f3 Budapest, Kuny Domokos \u00fat 1., 1012 Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Doktori Iskola Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ferencz","sequence":"additional","affiliation":[{"name":"Budapesti P\u00e9terfy S\u00e1ndor Utcai K\u00f3rh\u00e1z-Rendel\u0151int\u00e9zet, Seb\u00e9szeti Oszt\u00e1ly Budapest Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Doktori Iskola Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Alotaibi S, Hamadani M, Al-Mansour M, et al. 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Defining breast implant\n                    illness: a systematic review and meta-analysis of patient-reported symptoms.\n                    Plast Reconstr Surg Glob Open 2025; 13: e6773.\n                        https:\/\/doi.org\/10.1097\/GOX.0000000000006773","DOI":"10.1097\/GOX.0000000000006773"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Bresnick SD. Self-reported breast implant illness: the contribution\n                    of systemic illnesses and other factors to patient symptoms. Aesthet Surg J Open\n                    Forum 2023; 5: ojad030.\n                    https:\/\/doi.org\/10.1093\/asjof\/ojad030","DOI":"10.1093\/asjof\/ojad030"},{"key":"R12","unstructured":"U.S. Food and Drug Administration Breast implants. FDA strengthens\n                    breast implant safety requirements. 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Differential scanning calorimetry\n                    data of blood plasma in breast cancer patients. [Eml\u0151daganatos betegek\n                    v\u00e9rplazm\u00e1j\u00e1nak differenci\u00e1l p\u00e1szt\u00e1z\u00f3 kalorimetri\u00e1s vizsg\u00e1lata.] Magy Onkol.\n                    2012; 56: 274-279. [Hungarian]"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Lee M, Ponraja G, McLeod K, et al. Breast implant illness: a biofilm\n                    hypothesis. Plast Reconstr Surg Glob Open 2020; 8: e2755.\n                        https:\/\/doi.org\/10.1097\/GOX.0000000000002755","DOI":"10.1097\/GOX.0000000000002755"},{"key":"R17","doi-asserted-by":"crossref","unstructured":"Ferreira S, Barros AS, Marques M. Breast implant illness: symptoms,\n                    outcomes with explantation and potential etiologies - a systematic review and\n                    meta-analysis. 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[Hungarian]\n                    https:\/\/doi.org\/10.1556\/650.2026.33461","DOI":"10.1556\/650.2026.33461"},{"key":"R22","doi-asserted-by":"crossref","unstructured":"Caravantes-Cortes MI, Roldan-Valadez E, Zwojewski-Martinez RD, et\n                    al. Breast prosthesis syndrome: pathophysiology and management algorithm.\n                    Aesthetic Plast Surg. 2020; 44: 1423-3723.\n                        https:\/\/doi.org\/10.1007\/s00266-020-01663-9","DOI":"10.1007\/s00266-020-01663-9"},{"key":"R23","doi-asserted-by":"crossref","unstructured":"Taritsa IC, Jagasia PM, Boctor M, et al. Breast implant silicones\n                    and B cell-mediated immune responses: a systematic review of literature. JPRAS\n                    Open 2024; 41: 353-367.\n                    https:\/\/doi.org\/10.1016\/j.jpra.2024.06.013","DOI":"10.1016\/j.jpra.2024.06.013"},{"key":"R24","doi-asserted-by":"crossref","unstructured":"Nagy I, Kisa-Nagy V, Bozs\u00f3 Sz, et al. Effects of antioxidant and\n                    anti-inflammatory topical treatments on the phases of wound healing and their\n                    comparative analysis. [A sebgy\u00f3gyul\u00e1si f\u00e1zisok folyamatait befoly\u00e1sol\u00f3\n                    antioxid\u00e1ns \u00e9s antiinflammatorikus topik\u00e1lis kezel\u00e9sek hat\u00e1sai \u00e9s \u00f6sszehasonl\u00edt\u00f3\n                    elemz\u00e9s\u00fck.] Orv Hetil. 2026; 167: 109-118. [Hungarian]\n                        https:\/\/doi.org\/10.1556\/650.2026.33460","DOI":"10.1556\/650.2026.33460"},{"key":"R25","doi-asserted-by":"crossref","unstructured":"Khan I, Timsina L, Chauhan R, et al. Oxylipins in breast\n                    implant-associated systemic symptoms. Aesthet Surg J. 2024; 44: NP695-NP710.\n                        https:\/\/doi.org\/10.1093\/asj\/sjae128","DOI":"10.1093\/asj\/sjae128"},{"key":"R26","doi-asserted-by":"crossref","unstructured":"Trabilsy M, Haider SA, Borna S, et al. Exploring breast implant\n                    illness and its comorbid conditions: a systematic review and metaanalysis. J\n                    Plast Reconstr Aesthet Surg 2025; 105: 41-54.\n                        https:\/\/doi.org\/10.1016\/j.bjps.2025.03.026","DOI":"10.1016\/j.bjps.2025.03.026"},{"key":"R27","doi-asserted-by":"crossref","unstructured":"Ferencz A. Mesentery, the visceral \u201cambassador\u201d functioning as an\n                    abdominal organ. [Mesenterium, a hasi szervk\u00e9nt m\u0171k\u00f6d\u0151 visceralis \u201cnagyk\u00f6vet\u201d.]\n                    Orv Hetil. 2026; 167: 88-97. [Hungarian]\n                        https:\/\/doi.org\/10.1556\/650.2026.33463","DOI":"10.1556\/650.2026.33463"},{"key":"R28","doi-asserted-by":"crossref","unstructured":"Lieffering AS, Hommes JE, van der Hulst RR, et al. Breast implant\n                    illness revisited: a cohort study of health symptoms in women with implant-based\n                    reconstruction. 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Two hundreds cases\n                    of ASIA syndrome following silicone implants: a comparative study of 30 years\n                    and a review of current literature."},{"key":"R32","doi-asserted-by":"crossref","unstructured":"Alderman A, Gutowski K, Ahuja A, et al. ASPS clinical practice\n                    guideline summary on breast reconstruction with expanders and implants. Plast\n                    Reconstr Surg. 2014; 134: 648e-655e.\n                        https:\/\/doi.org\/10.1097\/PRS.0000000000000541","DOI":"10.1097\/PRS.0000000000000541"},{"key":"R33","doi-asserted-by":"crossref","unstructured":"Tanna N, Calobrace MB, Clemens MW, et al. Not all breast explants\n                    are equal: contemporary strategies in breast explantation surgery. Plast\n                    Reconstr Surg. 2021; 147: 808-818.\n                        https:\/\/doi.org\/10.1097\/PRS.0000000000007784","DOI":"10.1097\/PRS.0000000000007784"},{"key":"R34","doi-asserted-by":"crossref","unstructured":"Wee CE, Younis J, Isbester K, et al. Understanding breast implant\n                    illness, before and after explantation: a patient-reported outcomes study. Ann\n                    Plast Surg. 2020; 85(Suppl 1): S82-S86.\n                        https:\/\/doi.org\/10.1097\/SAP.0000000000002446","DOI":"10.1097\/SAP.0000000000002446"},{"key":"R35","doi-asserted-by":"crossref","unstructured":"Kaplan J, Rohrich R. Breast implant illness: a topic in review.\n                    Gland Surg. 2021; 10: 430-443.\n                    https:\/\/doi.org\/10.21037\/gs-20-231","DOI":"10.21037\/gs-20-231"},{"key":"R36","doi-asserted-by":"crossref","unstructured":"Clemens MW, Myckatyn TM, Di Napoli A, et al. 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