{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T10:54:39Z","timestamp":1715943279795},"reference-count":10,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,12,1]]},"abstract":"<jats:p>Bacterial meningitis continues to be associated with high morbidity and mortality rate worldwide, especially in the pediatric age group. This study was performed to identify the microbial etiologies of meningitis among 31 children, who were admitted in the Emergency Ward of a referral pediatric hospital in Iran. Culture identification showed that <jats:italic>Streptococcus pneumoniae<\/jats:italic> (12 subjects), <jats:italic>Haemophilus influenzae<\/jats:italic> (11 subjects) were the most common bacteria, followed by <jats:italic>Escherichia coli<\/jats:italic> (7 cases) and <jats:italic>Neisseria meningitidis<\/jats:italic> (only one case). Antibiotic susceptibility tests revealed that vancomycin had the best effect on <jats:italic>S. pneumoniae<\/jats:italic> in comparison with other antibiotics, whereas <jats:italic>H. influenzae<\/jats:italic> and <jats:italic>E. coli<\/jats:italic> were more susceptible to ceftriaxone, ceftazidime, and ceftizoxime than other antibiotics. In conclusion, despite the advances in antibiotic therapy and vaccine development, bacterial meningitis still is a health problem. <jats:italic>S. pneumoniae, H. influenzae<\/jats:italic>, and <jats:italic>N. meningitidis<\/jats:italic> are the main sources of bacterial meningitis, but other organisms such as <jats:italic>E. coli<\/jats:italic> should also be suspected, when a case is admitted to a referral pediatric hospital.<\/jats:p>","DOI":"10.1556\/amicr.58.2011.4.3","type":"journal-article","created":{"date-parts":[[2011,12,30]],"date-time":"2011-12-30T02:03:15Z","timestamp":1325210595000},"page":"273-278","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":3,"title":["Antimicrobial susceptibility profiles associated with bacterial meningitis among children: A referral hospital-based study in Iran"],"prefix":"10.1556","volume":"58","author":[{"given":"Mohammad","family":"Taghi Haghi-Ashtiani","sequence":"first","affiliation":[{"name":"1 Tehran University of Medical Sciences Pediatrics Center of Excellence, Children\u2019s Medical Center Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Setareh","family":"Mamishi","sequence":"additional","affiliation":[{"name":"2 Tehran University of Medical Sciences Infectious Disease Research Center Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasrin","family":"Shayanfar","sequence":"additional","affiliation":[{"name":"3 Tehran University of Medical Sciences Department of Anatomical and Clinical Pathology, Rasoul-e-Akram Hospital Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masoud","family":"Mohammadpour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahareh","family":"Yaghmaei","sequence":"additional","affiliation":[{"name":"1 Tehran University of Medical Sciences Pediatrics Center of Excellence, Children\u2019s Medical Center Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Abedini","sequence":"additional","affiliation":[{"name":"1 Tehran University of Medical Sciences Pediatrics Center of Excellence, Children\u2019s Medical Center Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narges","family":"Farahani","sequence":"additional","affiliation":[{"name":"1 Tehran University of Medical Sciences Pediatrics Center of Excellence, Children\u2019s Medical Center Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nima","family":"Rezaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.pcl.2005.02.011","article-title":"Bacterial meningitis in children","volume":"52","author":"Chavez-Bueno S.","year":"2005","journal-title":"Pediatr. 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