{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T11:14:39Z","timestamp":1783768479526,"version":"3.55.0"},"reference-count":43,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Microbiologica et Immunologica Hungarica"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1556\/amicr.60.2013.2.9","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T01:02:46Z","timestamp":1372986166000},"page":"187-199","source":"Crossref","is-referenced-by-count":12,"title":["<i>In vitro<\/i>efficacy of different irrigating solutions against polymicrobial human root canal bacterial biofilms"],"prefix":"10.1556","volume":"60","author":[{"given":"M\u00e1rk","family":"Fr\u00e1ter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Braunitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edit","family":"Urb\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"Bereczki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rk","family":"Antal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.joen.2008.10.024","article-title":"New bacterial compositions in root-filled teeth with periradicular lesions","volume":"35","author":"Schirrmeister J.F.","year":"2009","journal-title":"Journal of Endodontics"},{"key":"2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-2591.1997.tb00714.x","article-title":"Influence of infection at the time of root filling on the outcome of endodontic treatment of teeth with apical periodontitis","volume":"30","author":"Sjogren U.","year":"1997","journal-title":"International Endodontic Journal"},{"key":"3","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/00004770-200211000-00008","article-title":"The effectiveness of increased apical enlargement in reducing intracanal bacteria","volume":"28","author":"Card S.J.","year":"2002","journal-title":"Journal of Endodontics"},{"key":"4","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.joen.2006.04.011","article-title":"The influence of canal curvature on the mechanical efficacy of root canal irrigation in vitro using real-time imaging of bioluminescent bacteria","volume":"32","author":"Nguy D.","year":"2006","journal-title":"Journal of Endodontics"},{"key":"5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0099-2399(75)80097-5","article-title":"Scanning electron microscopic study of the efficacy of various irrigating solutions","volume":"1","author":"Baker N.A.","year":"1975","journal-title":"Journal of Endodontics"},{"key":"6","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0099-2399(84)80204-6","article-title":"Scanning electron microscopic investigation of the smeared layer on root canal walls","volume":"10","author":"Mader C.L.","year":"1984","journal-title":"Journal of Endodontics"},{"key":"7","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.joen.2006.07.003","article-title":"Cleaning efficacy and dentin micro-hardness after root canal irrigation with a strong acid electrolytic water","volume":"32","author":"Qing Y.","year":"2006","journal-title":"Journal of Endodontics"},{"key":"8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.joen.2010.11.006","article-title":"Comparison of the in vivo antimicrobial effectiveness of sodium hypochlorite and chlorhexidine used as root canal irrigants: a molecular microbiology study","volume":"37","author":"Rocas I.N.","year":"2011","journal-title":"Journal of Endodontics"},{"key":"9","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.joen.2009.01.018","article-title":"Enterococcus faecalis biofilms eradication by root canal irrigants","volume":"35","author":"Arias-Moliz M.T.","year":"2009","journal-title":"Journal of Endodontics"},{"key":"10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/00004770-200006000-00006","article-title":"Chemomechanical reduction of the bacterial population in the root canal after instrumentation and irrigation with 1%, 2.5%, and 5.25% sodium hypochlorite","volume":"26","author":"Siqueira J.F.","year":"2000","journal-title":"Journal of Endodontics"},{"key":"11","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0099-2399(98)80049-6","article-title":"Antimicrobial activity of 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate separately and combined, as endodontic irrigants","volume":"24","author":"Kuruvilla J.R.","year":"1998","journal-title":"Journal of Endodontics"},{"key":"12","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/S0099-2399(98)80023-X","article-title":"Antibacterial effects of endodontic irrigants on black-pigmented gram-negative anaerobes and facultative bacteria","volume":"24","author":"Siqueira J.F.","year":"1998","journal-title":"Journal of Endodontics"},{"key":"13","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1097\/00004770-200209000-00002","article-title":"Inactivation of the antibacterial activity of iodine potassium iodide and chlorhexidine digluconate against Enterococcus faecalis by dentin, dentin matrix, type-I collagen, and heat-killed microbial whole cells","volume":"28","author":"Portenier I.","year":"2002","journal-title":"Journal of Endodontics"},{"key":"14","first-page":"58","article-title":"Iodine compounds in endodontics: an update review","volume":"28","author":"Mohammadi Z.","year":"2009","journal-title":"Dentistry Today"},{"key":"15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.joen.2009.10.027","article-title":"Comparison of organic tissue dissolution capacities of sodium hypochlorite and chlorine dioxide","volume":"36","author":"Cobankara F.K.","year":"2010","journal-title":"Journal of Endodontics"},{"key":"16","first-page":"127","article-title":"[Changes in the therapy of pulpal diseases and periapical lesions according to the articles published in the journal Fogorvosi Szemle during the past 100 years) 1908\u20132008)]","volume":"101","author":"Nemes J.","year":"2008","journal-title":"Fogorvosi Szemle"},{"key":"17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0099-2399(87)80089-4","article-title":"Light and electron microscopic studies of root canal flora and periapical lesions","volume":"13","author":"Ramachandran Nair P.N.","year":"1987","journal-title":"Journal of Endodontics"},{"key":"18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.joen.2005.09.001","article-title":"Comparative evaluation of endodontic irrigants against Enterococcus faecalis biofilms","volume":"32","author":"Dunavant T.R.","year":"2006","journal-title":"Journal of Endodontics"},{"key":"19","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","article-title":"Bacterial biofilms: A common cause of persistent infections","volume":"284","author":"Costerton J.W.","year":"1999","journal-title":"Science"},{"key":"20","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/00004770-200110000-00004","article-title":"Susceptibilities of Enterococcus faecalis biofilms to some antimicrobial medications","volume":"27","author":"Lima K.C.","year":"2001","journal-title":"Journal of Endodontics"},{"key":"21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.joen.2011.10.007","article-title":"Prevalence of internal inflammatory root resorption","volume":"38","author":"Gabor C.","year":"2012","journal-title":"Journal of Endodontics"},{"key":"22","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.joen.2010.12.008","article-title":"Disinfecting oval-shaped root canals: Effectiveness of different supplementary approaches","volume":"37","author":"Alves F.R.","year":"2011","journal-title":"Journal of Endodontics"},{"key":"23","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.joen.2008.07.028","article-title":"Clinical implications and microbiology of bacterial persistence after treatment procedures","volume":"34","author":"Siqueira J.F.","year":"2008","journal-title":"Journal of Endodontics"},{"key":"24","first-page":"475","article-title":"Influence on periapical tissues of indigenous oral bacteria and necrotic pulp tissue in monkeys","volume":"89","author":"Moller A.J.","year":"1981","journal-title":"Scand J Dent Res"},{"key":"25","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00004770-200301000-00004","article-title":"Bacteriological evaluation of passive ultrasonic activation","volume":"29","author":"Spoleti P.","year":"2003","journal-title":"Journal of Endodontics"},{"key":"26","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.tripleo.2006.10.004","article-title":"The antimicrobial effects of root canal irrigation and medication","volume":"103","author":"Karim I.","year":"2007","journal-title":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},{"key":"27","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0099-2399(06)81170-2","article-title":"An evaluation of the action of different root canal irrigants on facultative aerobic-anaerobic, obligate anaerobic, and microaerophilic bacteria","volume":"25","author":"D\u2019Arcangelo C.","year":"1999","journal-title":"Journal of Endodontics"},{"key":"28","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.joen.2009.04.030","article-title":"Evaluation of the effect of two chlorhexidine preparations on biofilm bacteria in vitro: A three-dimensional quantitative analysis","volume":"35","author":"Shen Y.","year":"2009","journal-title":"Journal of Endodontics"},{"key":"29","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0966-842X(00)01913-2","article-title":"Mechanisms of biofilm resistance to antimicrobial agents","volume":"9","author":"Mah T.F.","year":"2001","journal-title":"Trends in Microbiology"},{"key":"30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/jac\/48.1.141","article-title":"Dormancy and persistence in chronic infection: role of the general stress response in resistance to chemotherapy","volume":"48","author":"Brown M.R.","year":"2001","journal-title":"The Journal of Antimicrobial Chemotherapy"},{"key":"31","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1128\/JCM.37.6.1771-1776.1999","article-title":"The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms","volume":"37","author":"Ceri H.","year":"1999","journal-title":"Journal of Clinical Microbiology"},{"key":"32","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1159\/000016600","article-title":"The anticariogenic effect of amine fluorides on Streptococcus sobrinus and glucosyltransferase in biofilms","volume":"34","author":"Shani S.","year":"2000","journal-title":"Caries Research"},{"key":"33","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.joen.2009.09.018","article-title":"The synergistic antimicrobial effect by mechanical agitation and two chlorhexidine preparations on biofilm bacteria","volume":"36","author":"Shen Y.","year":"2010","journal-title":"Journal of Endodontics"},{"key":"34","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.joen.2009.03.010","article-title":"Review of contemporary irrigant agitation techniques and devices","volume":"35","author":"Gu L.S.","year":"2009","journal-title":"Journal of Endodontics"},{"key":"35","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/0030-4220(94)90047-7","article-title":"Taxonomy, ecology, and pathogenicity of the root canal flora","volume":"78","author":"Sundqvist G.","year":"1994","journal-title":"Oral Surgery, Oral Medicine, and Oral Pathology"},{"key":"36","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0099-2399(82)80354-3","article-title":"In vivo evaluation of chlorhexidine gluconate solution and sodium hypochlorite solution as root canal irrigants","volume":"8","author":"Ringel A.M.","year":"1982","journal-title":"Journal of Endodontics"},{"key":"37","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.0143-2885.2004.00799.x","article-title":"In vitro evaluation of the effectiveness of irrigants and intracanal medicaments on microorganisms within root canals","volume":"37","author":"Menezes M.M.","year":"2004","journal-title":"International Endodontic Journal"},{"key":"38","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.tripleo.2007.01.027","article-title":"Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis","volume":"104","author":"Siqueira J.F.","year":"2007","journal-title":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},{"key":"39","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1097\/00004770-200411000-00009","article-title":"Soft tissue dissolution capacity of currently used and potential endodontic irrigants","volume":"30","author":"Naenni N.","year":"2004","journal-title":"Journal of Endodontics"},{"key":"40","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1600-0765.1973.tb02166.x","article-title":"Some antibacterial properties of chlorhexidine","volume":"12","author":"Hennessey T.S.","year":"1973","journal-title":"Journal of Periodontal Research. Supplement"},{"key":"41","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.joen.2005.09.014","article-title":"Root canal irrigants","volume":"32","author":"Zehnder M.","year":"2006","journal-title":"Journal of Endodontics"},{"key":"42","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1016\/j.joen.2010.08.032","article-title":"Bactericidal activity of stabilized chlorine dioxide as an endodontic irrigant in a polymicrobial biofilm tooth model system","volume":"36","author":"Lundstrom J.R.","year":"2010","journal-title":"Journal of Endodontics"},{"key":"43","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1097\/01.don.0000155223.87616.02","article-title":"An in vitro evaluation of the antibacterial efficacy of chlorine dioxide on E. faecalis in bovine incisors","volume":"31","author":"Eddy R.S.","year":"2005","journal-title":"Journal of Endodontics"}],"container-title":["Acta Microbiologica et Immunologica Hungarica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/akademiai.com\/doi\/pdf\/10.1556\/AMicr.60.2013.2.9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T20:59:27Z","timestamp":1596056367000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/amicr.60.2013.2.9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1556\/AMicr.60.2013.2.9"],"URL":"https:\/\/doi.org\/10.1556\/amicr.60.2013.2.9","relation":{},"ISSN":["1217-8950","1588-2640"],"issn-type":[{"value":"1217-8950","type":"print"},{"value":"1588-2640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}