{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:30:00Z","timestamp":1791347400028,"version":"4.3.1"},"reference-count":20,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,6,1]]},"abstract":"<jats:p>Even in asymptomatic cases of <jats:italic>Chlamydia trachomatis<\/jats:italic> infection, the aim of the antibiotic strategy is eradication of the pathogen so as to avoid the severe late sequelae, such as pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. Although first-line antimicrobial agents have been demonstrated to be predominantly successful in the treatment of <jats:italic>C. trachomatis<\/jats:italic> infection, treatment failures have been observed in some cases. Rich source of antimicrobial peptides was recently discovered in <jats:italic>Medicago<\/jats:italic> species, which act in plants as differentiation factors of the endosymbiotic bacterium partner. Several of these symbiotic plant peptides have proved to be potent killers of various bacteria <jats:italic>in vitro<\/jats:italic>. We show here that 7 of 11 peptides tested exhibited antimicrobial activity against <jats:italic>C. trachomatis<\/jats:italic> D, and that the killing activity of these peptides is most likely due to their interaction with specific bacterial targets.<\/jats:p>","DOI":"10.1556\/amicr.61.2014.2.12","type":"journal-article","created":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T01:05:38Z","timestamp":1403053538000},"page":"229-239","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":15,"title":["Anti-chlamydial effect of plant peptides"],"prefix":"10.1556","volume":"61","author":[{"given":"Emese","family":"Balogh","sequence":"first","affiliation":[{"name":"1 University of Szeged Department of Medical Microbiology and Immunobiology Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00edmea","family":"Mosolyg\u00f3","sequence":"additional","affiliation":[{"name":"1 University of 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