{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T19:56:11Z","timestamp":1760385371536},"reference-count":26,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,6,1]]},"abstract":"<jats:p>\n          <jats:italic>Streptococcus pneumoniae<\/jats:italic> causes life threatening infections and necessitate for impediment and controlling disease; to conquer this, information is needed about serotype distribution and patterns of antibiotic resistance. The present study was to determine the serotype distribution of <jats:italic>S. pneumoniae<\/jats:italic> isolated from the entire age group individual and to correlate this distribution with susceptibility. Cases of pneumococcal infections have been reviewed for serotyping and antibiotic susceptibility. Out of 117 pneumococcal isolates 45 (39%) were penicillin-resistant, 84 (72%) were erythromycin-resistant and 100% were co-trimoxazole resistant. The most frequently isolated serotypes were 23F, 19F, 14, 6B, 5, 6A, 19A and 9V. PCV7, PCV10 and PCV13 coverage was 68%, 79%, 87%, respectively. Similarly, there was similarity in PCV7 coverage for non invasive isolates (64.5%) and invasive isolates (72.2%). The study state that common pneumococcal serotypes were present in similar ways as reported in literature. A continuous survey of pneumococcal infected population is requirement and necessity for success of vaccination.<\/jats:p>","DOI":"10.1556\/amicr.61.2014.2.7","type":"journal-article","created":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T01:05:38Z","timestamp":1403053538000},"page":"173-179","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":9,"title":["Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections"],"prefix":"10.1556","volume":"61","author":[{"given":"Lakshmana","family":"Krishnappa","sequence":"first","affiliation":[{"name":"1 King Saud University Department of Clinical Laboratory Sciences, College of Applied Medical Sciences Po Box 10219 Riyadh 11433 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Marie","sequence":"additional","affiliation":[{"name":"1 King Saud University Department of Clinical Laboratory Sciences, College of Applied Medical Sciences Po Box 10219 Riyadh 11433 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"John","sequence":"additional","affiliation":[{"name":"2 Loyola College (Autonomous) Department of Zoology and Advance Biotechnology Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Dabwan","sequence":"additional","affiliation":[{"name":"1 King Saud University Department of Clinical Laboratory Sciences, College of Applied Medical Sciences Po Box 10219 Riyadh 11433 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Shashidhar","sequence":"additional","affiliation":[{"name":"1 King Saud University Department of Clinical Laboratory Sciences, College of Applied Medical Sciences Po Box 10219 Riyadh 11433 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","first-page":"51","article-title":"Causes and epidemiology of vaccine preventable infectious bacterial disease. The prospect and short out coming of vaccine","volume":"4","author":"James J.","year":"2012","journal-title":"Int J Pharm Pharm Sci."},{"key":"2","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1093\/cid\/cir142","article-title":"Advances in pneumococcal disease prevention, 13-valent pneumococcal conjugate vaccine for infants and children","volume":"52","author":"Paradiso P.R.","year":"2011","journal-title":"Clin Infect Dis"},{"key":"3","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/00365540500532852","article-title":"Serotypes of Streptococcus pneumoniae isolated from blood and cerebrospinal fluid related to vaccine serotypes and to clinical characteristics","volume":"38","author":"Berg S.","year":"2006","journal-title":"Scand J Infect Dis."},{"key":"4","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1086\/324527","article-title":"Clinical relevance of macrolide-resistant Streptococcus pneumoniae for community-acquired pneumonia","volume":"34","author":"Lynch J.P.","year":"2002","journal-title":"Clin Infect Dis."},{"key":"5","first-page":"CR471","article-title":"Antibiotic resistance of pediatric isolates of Streptococcus pneumoniae in a Saudi Arabian hospital from 1999 to 2004","volume":"12","author":"Al-Tawfiq J.A.","year":"2006","journal-title":"Med Sci Monit"},{"key":"6","doi-asserted-by":"crossref","first-page":"G32","DOI":"10.1016\/j.vaccine.2012.07.030","article-title":"Antibiotic resistance and serotype distribution of invasive pneumococcal diseases before and after introduction of pneumococcal conjugate vaccine in the Kingdom of Saudi Arabia (KSA)","volume":"30","author":"Shibl A.M.","year":"2012","journal-title":"Vaccine"},{"key":"7","first-page":"9","article-title":"Pneumococcal vaccination of older adults, conjugate or polysaccharide?","volume":"31","author":"Fedson D.S.","year":"2013","journal-title":"Hum Vaccin Immunother"},{"key":"8","doi-asserted-by":"crossref","first-page":"8870","DOI":"10.1016\/j.vaccine.2011.09.078","article-title":"Pre-clinical evaluation of a 15-valent pneumococcal conjugate vaccine (PCV15-CRM197) in an infant-rhesus monkey immunogenicity model","volume":"29","author":"Skinner J.M.","year":"2011","journal-title":"Vaccine"},{"key":"9","doi-asserted-by":"crossref","first-page":"e708","DOI":"10.1016\/j.ijid.2010.02.2242","article-title":"Epidemiology of invasive pneumococcal infection in children aged five years and under in Saudi Arabia, a five-year retrospective surveillance study","volume":"14","author":"Memish Z.A.","year":"2010","journal-title":"Int J Infect Dis"},{"key":"10","first-page":"1148","article-title":"Progress in introduction of pneumococcal conjugate vaccine \u2014 worldwide, 2000\u20132008","volume":"57","year":"2008","journal-title":"MMWR"},{"key":"11","doi-asserted-by":"crossref","first-page":"90","DOI":"10.5144\/0256-4947.2005.90","article-title":"Vaccination against invasive pneumococcal disease in Saudi Arabia, where do we stand?","volume":"25","author":"Frayha H.H.","year":"2005","journal-title":"Ann Saudi Med"},{"key":"12","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1128\/JCM.41.6.2378-2384.2003","article-title":"Serotyping Streptococcus pneumoniae by multiplex PCR","volume":"41","author":"Brito D.A.","year":"2003","journal-title":"J Clin Microbiol"},{"key":"13","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1128\/JCM.44.1.124-131.2006","article-title":"Sequential multiplex PCR approach for determining capsular serotypes of Streptococcus pneumoniae isolates","volume":"44","author":"Pai R.","year":"2006","journal-title":"J Clin Microbiol"},{"key":"14","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1099\/jmm.0.47347-0","article-title":"Sequential multiplex PCR for determining capsular serotypes of pneumococci recovered from Brazilian children","volume":"56","author":"Dias C.A.","year":"2007","journal-title":"J Med Microbio"},{"key":"15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1128\/JCM.37.1.263-265.1999","article-title":"Serotyping of Streptococcus pneumoniae by Coagglutination with 12 Pooled Antisera","volume":"37","author":"Lalitha M.K.","year":"1999","journal-title":"J Clin Microbiol"},{"key":"16","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1128\/JCM.00461-08","article-title":"Accuracy of phenotypic methods for identification of Streptococcus pneumoniae isolates included in surveillance programs","volume":"46","author":"Richter S.S.","year":"2008","journal-title":"J Clin Microbiol"},{"key":"17","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.1128\/JCM.42.10.4686-4696.2004","volume":"42","author":"Arbique J.C.","year":"2004","journal-title":"J Clin Microbiol"},{"key":"18","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing","year":"2009"},{"key":"19","volume-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically","year":"2009"},{"key":"20","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; Twenty-First Informational Supplement","year":"2011"},{"key":"21","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1016\/j.vaccine.2012.03.066","article-title":"Prevalence of Streptococcus pneumoniae serotypes causing invasive and non-invasive disease in South East Asia, a review","volume":"30","author":"Jauneikaite E.","year":"2012","journal-title":"Vaccine"},{"key":"22","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1093\/jac\/dkg171","article-title":"Antibiotic susceptibility and serotypes of Streptococcus pneumoniae isolates from Hungary","volume":"51","author":"Dobay O.","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1086\/518538","article-title":"Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults, an international study","volume":"45","author":"Alanee S.R.","year":"2007","journal-title":"Clin Infect Dis"},{"key":"24","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1186\/1471-2334-13-532","article-title":"Invasive pneumococcal infections in Vellore, India, clinical characteristics and distribution of serotypes","volume":"13","author":"Elisson C.","year":"2013","journal-title":"BMC Infect Dis"},{"key":"25","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1128\/AAC.48.6.2101-2107.2004","article-title":"High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study)","volume":"48","author":"Song J.H.","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"26","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/j.1469-0691.2008.02058.x","article-title":"Distribution of serotypes and antibiotic resistance of invasive pneumococcal disease isolates among children aged 5 years and under in Saudi Arabia (2000\u20132004)","volume":"14","author":"Shibl A.M.","year":"2008","journal-title":"Clin Microbiol Infect"}],"container-title":["Acta Microbiologica et Immunologica Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/61\/2\/article-p173.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/030\/61\/2\/article-p173.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T11:46:41Z","timestamp":1614599201000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/61\/2\/article-p173.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,1]]},"references-count":26,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/amicr.61.2014.2.7","relation":{},"ISSN":["1217-8950","1588-2640"],"issn-type":[{"value":"1217-8950","type":"print"},{"value":"1588-2640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,1]]}}}