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J. Neurosci."},{"key":"101","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(78)91125-3","article-title":"Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat","volume":"153","author":"Ricardo J.A.","year":"1978","journal-title":"Brain Res."},{"key":"102","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.peptides.2010.01.003","article-title":"The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: the former opens to the portal blood and the latter to the cerebrospinal fluid","volume":"31","author":"Rodr\u00edguez E.M.","year":"2010","journal-title":"Peptides"},{"key":"103","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0896-6273(04)00074-1","article-title":"Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob\/ob mice","volume":"41","author":"Roseberry A.G.","year":"2004","journal-title":"Neuron"},{"key":"104","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.brainres.2003.07.005","article-title":"Intraperitoneal injection of ghrelin induces Fos expression in the paraventricular nucleus of the hypothalamus in rats","volume":"991","author":"R\u00fcter J.","year":"2003","journal-title":"Brain Res."},{"key":"105","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.neuropharm.2011.10.008","article-title":"The role of the gut\/brain axis in modulating food intake","volume":"63","author":"Sam A.H.","year":"2012","journal-title":"Neuropharmacology"},{"key":"106","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/sj.bjp.0707422","article-title":"Endocannabinoids and the gastrointestinal tract: what are the key questions?","volume":"152","author":"Sanger G.J.","year":"2007","journal-title":"Br. 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