{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:04:00Z","timestamp":1770836640294,"version":"3.50.1"},"reference-count":25,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Physiologica Hungarica"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1556\/aphysiol.96.2009.2.6","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T01:18:36Z","timestamp":1242177516000},"page":"213-220","source":"Crossref","is-referenced-by-count":16,"title":["Berberine reduces the hypoxic-ischemic insult in rat pup brain"],"prefix":"10.1556","volume":"96","author":[{"given":"F.","family":"Benaissa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Mohseni-Rad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Rahimi-Moghaddam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massoud","family":"Mahmoudian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0074-7742(07)82008-3","article-title":"Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat","volume":"82","author":"Amantea D.","year":"2007","journal-title":"Int. Rev. Neurobiol."},{"key":"2","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1007\/s00401-004-0918-z","article-title":"Human cerebral infarct: a proposed histopathologic classification based on 137 cases","volume":"108","author":"Cadavid H.M.D.","year":"2004","journal-title":"Acta Neuropathol."},{"key":"3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00004647-200102000-00001","article-title":"Programmed cell death in cerebral ischemia","volume":"21","author":"Graham S.H.","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"4","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0006-8993(01)02640-3","article-title":"Activated astrocytes with glycogen accumulation in ischemic penumbra during the early stage of brain infarction: immunohistochemical and electron microscopic studies","volume":"909","author":"Kajihara H.","year":"2001","journal-title":"Brain Res."},{"key":"5","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/BF02884757","article-title":"Influence of berberine on the blood pressure of rabbits","volume":"3","author":"Ko S.T.","year":"1980","journal-title":"Arch. Pharm. Res."},{"key":"6","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.canlet.2003.09.002","article-title":"The anti-inflammatory potential of berberine in vitro and in vivo","volume":"203","author":"Kuo C.-L.","year":"2004","journal-title":"Cancer Letters"},{"key":"7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.phrs.2007.06.003","article-title":"Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of kappa-B degradation in human lung cells","volume":"56","author":"Lee C.H.","year":"2007","journal-title":"Pharmacol. Res."},{"key":"8","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1152\/physrev.1999.79.4.1431","article-title":"Ischemic cell death in brain neurons","volume":"79","author":"Lipton P.","year":"1999","journal-title":"Physiol. Rev."},{"key":"9","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1159\/000028331","article-title":"The antihypertensive effect of the berberine derivative 6-protoberberine in spontaneously hypertensive rats","volume":"59","author":"Liu J.C.","year":"1999","journal-title":"Pharmacol."},{"key":"10","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1556\/APhysiol.90.2003.4.4","article-title":"Reduction of the prenatal hypoxic-ischemic brain edema with Noscapine","volume":"90","author":"Mahmoudian M.","year":"2003","journal-title":"Acta Physiol. Hung."},{"key":"11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.neuint.2005.05.014","article-title":"ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia","volume":"47","author":"Melani A.","year":"2005","journal-title":"Neurochem. Int."},{"key":"12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0027-5107(93)90189-M","article-title":"Genotoxicity of the isoquinoline alkaloid berberine in prokaryotic and eukaryotic organisms","volume":"286","author":"Pasqual M.S.","year":"1993","journal-title":"Mut. Res."},{"key":"13","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1212\/WNL.43.3_Part_1.461","article-title":"Acute hypertension after stroke: the scientific basis for treatment decisions","volume":"43","author":"Powers W.J.","year":"1993","journal-title":"Neurol."},{"key":"14","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/infdis\/155.5.979","article-title":"Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholera","volume":"155","author":"Rabbani G.H.","year":"1987","journal-title":"J. Infect. Dis."},{"key":"15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic-ischemic brain damage in the rat","volume":"9","author":"Rice J.E.","year":"1981","journal-title":"Ann. Neurol."},{"key":"16","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.STR.12.6.840","article-title":"Vascular supply pattern to rat caudatoputamen and globus pallidus: scanning electromicroscopic study of vascular endocasts of stroke-prone vessels","volume":"12","author":"Rieke G.K.","year":"1981","journal-title":"Stroke"},{"key":"17","first-page":"86","article-title":"Chinese herbs for diabetes mellitus","volume":"7","author":"Sun F.L.","year":"2002","journal-title":"Chinese Prescription Drug"},{"key":"18","first-page":"98","article-title":"Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion","volume":"30","author":"Wu J.F.","year":"1995","journal-title":"Yao Xue Xue Bao"},{"key":"19","first-page":"167","article-title":"Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats","volume":"13","author":"Xuan B.","year":"1992","journal-title":"Zhongguo Yao Li Xue Bao"},{"key":"20","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1248\/bpb.29.623","article-title":"Berberry extract reduces neuronal damage and N-Methyl-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia","volume":"29","author":"Yoo K.Y.","year":"2006","journal-title":"Biol. Pharm. Bull."},{"key":"21","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0002-9149(03)00533-2","article-title":"Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy","volume":"92","author":"Zeng X.-H.","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"22","first-page":"452","article-title":"Protective effect of berberine on cardiac myocyte injured by ischemiareperfusion","volume":"34","author":"Zheng L.","year":"2003","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"key":"23","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0022-3565(24)39141-4","article-title":"The effect of berberine chloride on experimental colitis in rats in vivo and in vitro","volume":"294","author":"Zhou H.","year":"2000","journal-title":"J. Pharmacol. Exper. Therapeut."},{"key":"24","first-page":"130","article-title":"Effects of tetrahydroberberine on ischemic and reperfused myocardium in rats","volume":"14","author":"Zhou J.","year":"1993","journal-title":"Zhongguo Yao Li Xue Bao"},{"key":"25","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1471-2202-7-78","article-title":"Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer\u2019s disease","volume":"7","author":"Zhu F.","year":"2006","journal-title":"BMC Neurosci"}],"container-title":["Acta Physiologica Hungarica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/aphysiol.96.2009.2.6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T11:06:44Z","timestamp":1739099204000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/aphysiol.96.2009.2.6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1556\/APhysiol.96.2009.2.6"],"URL":"https:\/\/doi.org\/10.1556\/aphysiol.96.2009.2.6","relation":{},"ISSN":["0231-424X","1588-2683"],"issn-type":[{"value":"0231-424X","type":"print"},{"value":"1588-2683","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}