{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T20:50:34Z","timestamp":1763499034103},"reference-count":28,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6,1]]},"abstract":"<jats:p>The objective of this study was to improve the reproductive efficiency of dairy cows with puerperal metritis (PM) subsequent to retained placenta (RP) using a two-step treatment strategy. A total of 188 postpartum cows, aged from 2 to 8 years, were utilised for 2 experiments. In Experiment 1, cows affected with RP\/PM were randomly assigned to two treatment groups. Cows in Group A (n = 17) were treated with 600 mg of ceftiofur intramuscularly for 3 days followed by intrauterine lavage with 0.1% chlorhexidine and infusion with 0.5% povidoneiodine, while cows in Group B (n = 16) received two intrauterine infusions, first with 5 g of oxytetracycline and then with 0.5% povidone-iodine. Cows with normal postpartum findings were regarded as the healthy control group (n = 26). Ultrasonographic examination revealed that the ovarian activities including the appearance of a dominant follicle and days to first ovulation of the cows in Group A during the early postpartum period differed from those of Group B (P &lt; 0.05), which coincided with the results of uterine swabbing for bacteriology. In Experiment 2, cows with normal postpartum findings were allocated to Group D (n = 78), which received an ovulation protocol (GnRH - 7 d PGF<jats:sub>2\u03b1<\/jats:sub> - 48 h hCG - 24 h AI) on day 50 \u00b1 2 postpartum. Cows affected with PM were randomly divided into two groups, Group E (n = 25) combined the treatments applied in Groups A and D, while Group F (n = 26) repeated the treatment administered in Group E except for uterine lavage. The results indicated that the pregnancy rate within 150 days postpartum and the mean days open in Group E (76.0% and 106.3 \u00b1 4.6 days, respectively) were significantly different from those in Group F (38.5% and 137.9 \u00b1 10.9 days, respectively) (P &lt; 0.05). This study suggests that reproductive efficiency could be improved by using the two-step treatment to regulate uterine involution and an early resumption of ovarian function in cows with RP\/PM.<\/jats:p>","DOI":"10.1556\/avet.2011.004","type":"journal-article","created":{"date-parts":[[2011,4,6]],"date-time":"2011-04-06T12:59:14Z","timestamp":1302094754000},"page":"247-256","source":"Crossref","is-referenced-by-count":11,"title":["Strategy for the treatment of puerperal metritis and improvement of reproductive efficiency in cows with retained placenta"],"prefix":"10.1556","volume":"59","author":[{"given":"Wen-Bor","family":"Liu","sequence":"first","affiliation":[{"name":"1 National Chung Hsing University Department of Animal Science, College of Agriculture and Natural Resources 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Te","family":"Chuang","sequence":"additional","affiliation":[{"name":"2 National Chung Hsing University Department of Veterinary Medicine 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Lin","family":"Shyu","sequence":"additional","affiliation":[{"name":"2 National Chung Hsing University Department of Veterinary Medicine 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao-Chin","family":"Chang","sequence":"additional","affiliation":[{"name":"3 National Chung Hsing University Graduate Institute of Veterinary Public Health, College of Veterinary Medicine 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Jack","sequence":"additional","affiliation":[{"name":"2 National Chung Hsing University Department of Veterinary Medicine 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huo-Cheng","family":"Peh","sequence":"additional","affiliation":[{"name":"1 National Chung Hsing University Department of Animal Science, College of Agriculture and Natural Resources 250 Kuo-Kuang Rd. Taichung 40227 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacky","family":"Chan","sequence":"additional","affiliation":[{"name":"2 National Chung Hsing University Department of Veterinary Medicine 250 Kuo-Kuang Rd. 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