{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:57:59Z","timestamp":1788908279540,"version":"build-2803163510"},"reference-count":26,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,6,1]]},"abstract":"<jats:p>In this study,<jats:italic>Staphylococcus aureus<\/jats:italic>strains (n = 110) isolated from seven ewe flocks in Sanliurfa, Turkey were screened for antibiotic resistance and biofilmforming ability as well as for genes associated with antibiotic resistance and biofilm-forming ability. All isolates were found to be susceptible to oxacillin, gentamicin, clindamycin, cefoxitin, tetracycline, vancomycin, amoxicillin-clavulanic acid, ciprofloxacin and sulphamethoxazole-trimethoprim. The percent proportions of strains resistant to penicillin G, ampicillin and erythromycin were 27.2% (n = 30), 25.4% (n = 28) and 6.3% (n = 7), respectively. Regarding the antibiotic resistance genes, 32 (29%) isolates carried the<jats:italic>bla<\/jats:italic>Z and 8 (7.2%) the<jats:italic>erm<\/jats:italic>C gene. Other resistance genes were not detected in the isolates. All isolates showed biofilm-forming ability on Congo red agar (CRA), while 108 (98.18%) and 101 (91.81%) of them were identified as biofilm producers by the use of standard tube (ST) and microplate (MP) methods, respectively. All isolates carried the<jats:italic>ica<\/jats:italic>A and<jats:italic>ica<\/jats:italic>D genes but none of them harboured the<jats:italic>bap<\/jats:italic>gene. The results demonstrated that<jats:italic>S. aureus<\/jats:italic>isolates from gangrenous mastitis were mainly resistant to penicillins (which are susceptible to the staphylococcal beta-lactamase enzyme), and less frequently to erythromycin. Furthermore, all of the<jats:italic>S. aureus<\/jats:italic>isolates produced biofilm which was considered a potential virulence factor in the pathogenesis of staphylococcal mastitis.<\/jats:p>","DOI":"10.1556\/avet.2012.016","type":"journal-article","created":{"date-parts":[[2012,5,20]],"date-time":"2012-05-20T15:51:45Z","timestamp":1337529105000},"page":"189-197","source":"Crossref","is-referenced-by-count":15,"title":["Investigation of the antibiotic resistance and biofilm formation of Staphylococcus aureus strains isolated from gangrenous mastitis of ewes"],"prefix":"10.1556","volume":"60","author":[{"given":"Osman","family":"Tel","sequence":"first","affiliation":[{"name":"1 Harran University Department of Microbiology, Faculty of Veterinary Medicine Eyyubiye Campus Eyyubiye, Sanliurfa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zkan","family":"Aslanta\u015f","sequence":"additional","affiliation":[{"name":"2 Mustafa Kemal University Department of Microbiology, Faculty of Veterinary Medicine Hatay Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oktay","family":"Keskin","sequence":"additional","affiliation":[{"name":"1 Harran University Department of Microbiology, Faculty of Veterinary Medicine Eyyubiye Campus Eyyubiye, Sanliurfa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"3 Mustafa Kemal University Department of Biology, Faculty of Arts and Sciences Hatay Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cemil","family":"Demir","sequence":"additional","affiliation":[{"name":"4 Mustafa Kemal University Department of Microbiology, Faculty of Medicine Hatay Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.vetmic.2008.10.024","article-title":"Antimicrobial susceptibility of udder pathogens from cases of acute clinical mastitis in dairy cows","volume":"136","author":"Bengtsson B.","year":"2009","journal-title":"Vet. 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