{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T02:08:45Z","timestamp":1773626925679,"version":"3.50.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>Canine babesiosis is a frequent and clinically significant tick-borne disease. Sixty symptomatic dogs with clinical findings compatible with babesiosis were included in this study conducted in Serbia. After clinical examination, blood samples were taken for microscopic examination, complete blood count (CBC), Canine SNAP 4Dx Test, DNA analyses and sequencing. The main clinical signs included apathy, anorexia, fever, brown\/red discoloration of urine, pale mucous membranes, icterus, splenomegaly, and vomiting. The main clinicopathological findings in <jats:italic>Babesia<\/jats:italic> infections were a slight to severe thrombocytopenia and a mild to very severe normocytic normochromic anaemia. Microscopic evaluation revealed 58 positive samples with the presence of large and small intraerythrocytic piroplasms in 57 and 1 sample(s), respectively. No co-infections were found using SNAP test. Two <jats:italic>Babesia<\/jats:italic> species, <jats:italic>B. canis<\/jats:italic> (58\/60) and <jats:italic>B. gibsoni<\/jats:italic> (2\/60), were differentiated by polymerase chain reaction\u2013restriction fragment length polymorphism (PCR-RFLP). Species identification was further confirmed by sequencing PCR products of <jats:italic>B. gibsoni<\/jats:italic> samples and six randomly selected <jats:italic>B. canis<\/jats:italic> samples. All dogs were treated with imidocarb dipropionate (6.6 mg\/kg of body weight), given intramuscularly twice at an interval of 14 days. This report presents the first molecular evidence of the occurrence of <jats:italic>B. gibsoni<\/jats:italic> and <jats:italic>B. canis<\/jats:italic>, confirmed by DNA sequencing, in sick dogs from Serbia.<\/jats:p>","DOI":"10.1556\/avet.2015.017","type":"journal-article","created":{"date-parts":[[2015,6,8]],"date-time":"2015-06-08T03:54:30Z","timestamp":1433735670000},"page":"199-208","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":50,"title":["Clinical babesiosis and molecular identification of Babesia canis and Babesia gibsoni infections in dogs from Serbia"],"prefix":"10.1556","volume":"63","author":[{"given":"Darko","family":"Davitkov","sequence":"first","affiliation":[{"name":"Department of Equine, Small Animal, Poultry and Wild Animal Diseases University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milos","family":"Vucicevic","sequence":"additional","affiliation":[{"name":"Department of Equine, Small Animal, Poultry and Wild Animal Diseases University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jevrosima","family":"Stevanovic","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Veterinary Medicine, University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanja","family":"Krstic","sequence":"additional","affiliation":[{"name":"Department of Equine, Small Animal, Poultry and Wild Animal Diseases University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Snezana","family":"Tomanovic","sequence":"additional","affiliation":[{"name":"Laboratory for Medical Entomology, Department for Parasitology, Institute for Medical Research, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uros","family":"Glavinic","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Veterinary Medicine, University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran","family":"Stanimirovic","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Veterinary Medicine, University of Belgrade, Bul. oslobodjenja 18, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p199.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p199.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p199.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T20:52:11Z","timestamp":1686171131000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p199.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/avet.2015.017","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6]]}}}