{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:52:49Z","timestamp":1758397969697},"reference-count":14,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:p>\n          <jats:italic>In vitro<\/jats:italic> antimicrobial sensitivity of 12 Hungarian isolates and the type strain ATCC 33144 of <jats:italic>Actinobaculum suis<\/jats:italic> to different antimicrobial compounds was determined both by the agar dilution and by the disc diffusion method. By agar dilution, MIC<jats:sub>50<\/jats:sub> values in the range of 0.05-3.125\u00b5g\/ml were determined for penicillin, ampicillin, ceftiofur, doxycycline, tylosin, pleuromutilins, chloramphenicol, florfenicol, enrofloxacin and lincomycin. The MIC<jats:sub>50<\/jats:sub> value of oxytetracycline and spectinomycin was 6.25 and 12.5\u00b5g\/ml, respectively. For ofloxacin, flumequine, neomycin, streptomycin, gentamicin, nalidixic acid, nitrofurantoin and sulphamethoxazole + trimethoprim MIC<jats:sub>50<\/jats:sub> values were in the range of 25-100\u00b5g\/ml. With the disc diffusion method, all strains were sensitive to penicillin, cephalosporins examined, chloramphenicol and florfenicol, tetracyclines examined, pleuromutilins, lincomycin and tylosin. Variable sensitivity was observed for fluoroquinolones (flumequine, enrofloxacin, ofloxacin), most of the strains were susceptible to marbofloxacin. Almost all strains were resistant to aminoglycosides but most of them were sensitive to spectinomycin. A strong correlation was determined for disc diffusion and MIC results (Spearman's rho 0.789, p&lt;0001). MIC values of the type strain and MIC<jats:sub>50<\/jats:sub> values of other tested strains did not differ significantly. Few strains showed a partially distinct resistance pattern for erythromycin, lincomycin and ampicillin in both methods.<\/jats:p>","DOI":"10.1556\/avet.51.2003.1.5","type":"journal-article","created":{"date-parts":[[2004,7,14]],"date-time":"2004-07-14T13:51:59Z","timestamp":1089813119000},"page":"53-59","source":"Crossref","is-referenced-by-count":6,"title":["In vitro sensitivity of Hungarian Actinobaculum suis strains to selected antimicrobials"],"prefix":"10.1556","volume":"51","author":[{"given":"I.","family":"Biksi","sequence":"first","affiliation":[{"name":"1 Department of Pathology, Faculty of Veterinary Science, Szent Istv\u00e1n University Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Major","sequence":"additional","affiliation":[{"name":"2 Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent Istv\u00e1n University Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Fodor","sequence":"additional","affiliation":[{"name":"3 Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent Istv\u00e1n University Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"et al.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"4","unstructured":"Dreau, D. and Laval, A. 2000: Effect of ceftiofur in the control of urinary infections in sows: results of a field trial in a French farrow to finish unit. Proc. 16th Int. Congr. Pig Vet. Soc. Melbourne, Australia. p. 105."},{"key":"5","unstructured":"H\u00f8gh, P., Blom, E. and Larsen, J. L. 1984: Corynebacterium suis infection in Danish pigs. Proc. 8th Int. Congr. Pig Vet. Soc., Ghent, Belgium. p. 150."},{"key":"6","first-page":"110","article-title":"Untersuchungen zum Vorkommen von Corynebacterium suis bei Wild- und Hausschweinen in der Bundesrepublik Deutschland.","volume":"89","author":"J. T. Jones","year":"1982","journal-title":"Dtsch. tier\u00e4rztl. Wschr."},{"key":"7","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1099\/00207713-47-3-899","article-title":"Characterisation of some actinomyces-like isolates from human clinical specimens: reclassification of Actinomyces suis (Soltys and Spratling) as Actinobaculum suis comb. nov. and description of Actinobaculum schaali.","volume":"47","author":"P. Lawson","year":"1997","journal-title":"Int. J. Syst. 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In: Veterinary Clinics of North America: Food Animal Practice 8:3, Swine Reproduction. pp. 641-660."}],"container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/51\/1\/article-p53.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/avet.51.2003.1.5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T09:42:11Z","timestamp":1590140531000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/avet.51.2003.1.5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":14,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/avet.51.2003.1.5","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"type":"print","value":"0236-6290"},{"type":"electronic","value":"1588-2705"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}