{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:59:44Z","timestamp":1778792384006,"version":"3.51.4"},"reference-count":25,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,9,1]]},"abstract":"<jats:p>Serum amyloid A (SAA) is of interest as the circulating precursor of amyloid A protein, the fibrillar component of AA (secondary) amyloid deposits, and also as an extremely sensitive and rapid major acute phase protein. Serum concentrations of acute phase proteins (APPs) provide valuable information about the diagnosis and prognosis of various diseases, and thus the relevance of APPs for monitoring the health status of domestic animals is widely accepted. More importantly, the measurement of SAA concentration assists in assessing the prognosis in secondary amyloidosis, which is a common disease of geese, affecting an increasing number of animals. In the present study we introduce a highly sensitive goose-specific ELISA method for measuring SAA concentration in goose serum or plasma samples. Samples were taken from geese of the Landes Grey and Hungarian White breeds, which were stimulated for an acute phase reaction by administration of a commercially available fowl cholera vaccine containing inactivated \n <jats:italic>Pasteurella multocida<\/jats:italic>\n . Strong and characteristically rapid acute phase responses were measured in both breeds, peaking at approximately 24 h after inoculation. The maximum SAA concentration was 1200 \u03bcg\/ml. At 72 h post-inoculation, the concentrations returned to pre-inoculation values. There was significantly (p = 0.004) less intense response in the control groups; however, a very mild increase of SAA levels was detected due to the stress inevitably caused by the sampling procedure.<\/jats:p>","DOI":"10.1556\/avet.55.2007.3.9","type":"journal-article","created":{"date-parts":[[2007,8,14]],"date-time":"2007-08-14T19:14:00Z","timestamp":1187118840000},"page":"349-357","source":"Crossref","is-referenced-by-count":11,"title":["Evaluation of goose serum amyloid a acute phase response by enzyme-linked immunosorbent assay"],"prefix":"10.1556","volume":"55","author":[{"given":"Be\u00e1ta","family":"Kov\u00e1cs","sequence":"first","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Physiology and Biochemistry, Faculty of Veterinary Science H-1078 Budapest Istv\u00e1n u. 2 Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathilda","family":"Toussaint","sequence":"additional","affiliation":[{"name":"2 Utrecht University Department of Pathobiology, Faculty of Veterinary Medicine Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gruys","sequence":"additional","affiliation":[{"name":"2 Utrecht University Department of Pathobiology, Faculty of Veterinary Medicine Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibolya","family":"F\u00e1bi\u00e1n","sequence":"additional","affiliation":[{"name":"3 Szent Istv\u00e1n University Department of Biomathematics and Informatics, Faculty of Veterinary Science Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Szil\u00e1gyi","sequence":"additional","affiliation":[{"name":"4 E\u00f6tv\u00f6s Lor\u00e1nd University Department of Biochemistry, Faculty of Science Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Janan","sequence":"additional","affiliation":[{"name":"5 Szent Istv\u00e1n University Department of Applied Ethology, Institute of Environmental Management G\u00f6d\u00f6ll\u0151 Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Rudas","sequence":"additional","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Physiology and Biochemistry, Faculty of Veterinary Science H-1078 Budapest Istv\u00e1n u. 2 Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1051\/vetres:2005017","article-title":"The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig","volume":"36","author":"Campbell F. 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