{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:25:56Z","timestamp":1777411556111,"version":"3.51.4"},"reference-count":37,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,3,1]]},"abstract":"<jats:p>The objective of this study was to determine some metabolic and other factors predicting the risk of postpartum uterine disease (PUD), and the effects of puerperal metritis (PM) on metabolic status, reproduction and milk yield were analysed. A total of 105 Holstein-Friesian cows were included, and sampled on day &lt; \u221214 prepartum and days 4, 10\u201314, 28\u201335 and 56\u201363 postpartum for metabolic tests. From day 4 the development of PUD, and from days 28\u201335 the ovarian activity was monitored. When grade \u2265 1 + ketonuria was present on day 4 postpartum, this indicated a higher probability of PUD [odds ratio (OR) 2.64; P &lt; 0.05] including PM occurring on days 10\u201314 (OR: 2.65; P &lt; 0.05). Plasma nonesterified fatty acid (NEFA) concentrations &gt; 0.200 mmol\/l on days &lt; \u221214 prepartum indicated a higher risk of uterine diseases (OR: 3.44; P &lt; 0.05). The odds of PUD increased, depending on whether a body condition score (BCS) loss of \u2265 1.0 occurred between days &lt; \u221214 and 28\u201335 (OR: 2.82; P &lt; 0.05), between days &lt; \u221214 and 10\u201314 (OR: 4.79; P &lt; 0.01) or between days 10\u201314 and 28\u201335 (OR: 10.81; P &lt; 0.01). PM was more probable (OR: 27.3; P &lt; 0.001) in cows with retained placenta. The risk of uterine diseases was lower in multiparous than in primiparous cows (OR: 0.29; P &lt; 0.01). PM increased the risk of ovarian inactivity between days 28 and 35 (OR: 2.83; P &lt; 0.05). Cows affected with PM (PM+ cows) showed lower milk production on day 4 (kg; P &lt; 0.05) and lower milk production (P &lt; 0.05), milk fat and milk protein production (kg; P &lt; 0.01; P &lt; 0.01) in the first 100 days of lactation than did PM\u2212 cows.<\/jats:p>","DOI":"10.1556\/avet.57.2009.1.16","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T02:05:25Z","timestamp":1236132325000},"page":"155-169","source":"Crossref","is-referenced-by-count":17,"title":["Risk assessment of postpartum uterine disease and consequences of puerperal metritis for subsequent metabolic status, reproduction and milk yield in dairy cows"],"prefix":"10.1556","volume":"57","author":[{"given":"L\u00e1szl\u00f3","family":"K\u00f6nyves","sequence":"first","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science Istv\u00e1n u. 2 H-1078 Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ott\u00f3","family":"Szenci","sequence":"additional","affiliation":[{"name":"2 Szent Istv\u00e1n University Clinic for Large Animals, Faculty of Veterinary Science \u00dcll\u0151 Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktor","family":"Jurkovich","sequence":"additional","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science Istv\u00e1n u. 2 H-1078 Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3n\u00e9","family":"Tegzes","sequence":"additional","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science Istv\u00e1n u. 2 H-1078 Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"Tiri\u00e1n","sequence":"additional","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science Istv\u00e1n u. 2 H-1078 Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Solymosi","sequence":"additional","affiliation":[{"name":"3 Szent Istv\u00e1n University Department of Biomathematics and Informatics, Faculty of Veterinary Science Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyula","family":"Gyulay","sequence":"additional","affiliation":[{"name":"4 Private Veterinarian Martonv\u00e1s\u00e1r Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Endre","family":"Brydl","sequence":"additional","affiliation":[{"name":"1 Szent Istv\u00e1n University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science Istv\u00e1n u. 2 H-1078 Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","volume-title":"Categorical Data Analysis","author":"Agresti A.","year":"1990"},{"key":"2","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.3168\/jds.S0022-0302(92)77951-X","article-title":"Effect of prepartum dry matter intake on liver triglyceride concentration and postpartum lactation","volume":"75","author":"Bertics S. J.","year":"1992","journal-title":"J. Dairy Sci."},{"key":"3","first-page":"600","article-title":"Prevention of peripartal metabolic disorders with multiphase feeding in dairy cows (in Hungarian, with English abstract)","volume":"50","author":"Brydl E.","year":"1995","journal-title":"Magyar \u00c1llatorvosok Lapja"},{"key":"4","first-page":"393","article-title":"Occurrence of subclinical metabolic disorders in dairy cows in Hungary in 2001 (in Hungarian, with English abstract)","volume":"125","author":"Brydl E.","year":"2003","journal-title":"Magyar \u00c1llatorvosok Lapja"},{"key":"5","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0093-691X(03)00126-2","article-title":"Heat stress and seasonal effects on reproduction in the dairy cow \u2014 a review","volume":"60","author":"Rensis F.","year":"2003","journal-title":"Theriogenology"},{"key":"6","first-page":"116","article-title":"Adaptive changes of the ruminal mucosa and their functional and clinical significance","volume":"20","author":"Dirksen G. H.","year":"1999","journal-title":"Bov. Pract."},{"key":"7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1136\/vr.113.3.53","article-title":"Blood composition and liver fat in post parturient dairy cows","volume":"113","author":"Ga\u00e1l T.","year":"1983","journal-title":"Vet. Rec."},{"key":"8","first-page":"51","article-title":"Managing the transition cow \u2014 considerations for optimising energy and protein balance and immune function","volume":"11","author":"Goff J. P.","year":"2003","journal-title":"Cattle Pract."},{"key":"9","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.2527\/1995.7392820x","article-title":"Impact of changes in organic nutrient metabolism on feeding the transition dairy cow","volume":"73","author":"Grummer R. R.","year":"1995","journal-title":"J. Anim. Sci."},{"key":"10","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.cvfa.2004.06.013","article-title":"Dry matter intake and energy balance in the transition period","volume":"20","author":"Grummer R. R.","year":"2004","journal-title":"Vet. Clin. Food Anim. Sci."},{"key":"11","volume-title":"Obstetrics and Reproduction of Domestic Animals (in Hungarian)","author":"Haraszti J.","year":"1993"},{"key":"12","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1210\/endo.141.3.7393","article-title":"Prostaglandins mediate the endotoxin-induced suppression of pulsatile gonadotropin-releasing hormone and luteinising hormone secretion in the ewe","volume":"141","author":"Harris T. G.","year":"2000","journal-title":"Endocrinology"},{"key":"13","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.3168\/jds.S0022-0302(02)74431-7","article-title":"Animal and dietary factors affecting feed intake during the pre-fresh transition period in Holsteins","volume":"85","author":"Hayrili A.","year":"2002","journal-title":"J. Dairy Sci."},{"key":"14","volume-title":"Nonparametric Statistical Methods","author":"Hollander M.","year":"1999"},{"key":"15","doi-asserted-by":"crossref","first-page":"883","DOI":"10.3168\/jds.S0022-0302(03)73671-6","article-title":"Effects of feed intensity during the dry period. 2. Metabolic and hormonal responses","volume":"86","author":"Holtenius K.","year":"2003","journal-title":"J. Dairy Sci."},{"key":"16","first-page":"689","article-title":"Changes in certain lipid components of the blood plasma and liver of dairy cows during the perinatal period (in Hungarian, with English abstract)","volume":"37","author":"Husv\u00e9th F.","year":"1982","journal-title":"Magyar \u00c1llatorvosok Lapja"},{"key":"17","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1439-0531.1999.tb01246.x","article-title":"Uterine bacteriology, resumption of cyclic ovarian activity and fertility in postpartum cows kept in larges-cale dairy herds","volume":"34","author":"Huszenicza G.","year":"1999","journal-title":"Reprod. Domest. Anim."},{"key":"18","volume-title":"Production Diseases in Farm Animals. Book of Abstracts of 10th IPCD","author":"Huszenicza G.","year":"1998"},{"key":"19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.17221\/5824-VETMED","article-title":"Clinical endocrinology of thyroid gland function in ruminants","volume":"47","author":"Huszenicza G.","year":"2002","journal-title":"Vet. Med. Czech"},{"key":"20","first-page":"175","article-title":"Feeding and management-related diseases in the transition cow. Physiological adaptations around calving and strategies to reduce feeding-related diseases","volume":"126","author":"Ingvartsen K. L.","year":"2006","journal-title":"Anim. Feed Sci. Technol."},{"key":"21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1051\/vetres:2002054","article-title":"Metabolic changes in early lactation and impaired reproductive performance in dairy cows","volume":"34","author":"Jorritsma R.","year":"2003","journal-title":"Vet. Res."},{"key":"22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0167-5877(94)00438-O","article-title":"Risk factors for metritis in Michigan dairy cattle using herd- and cow-based modelling approaches","volume":"23","author":"Kaneene J. B.","year":"1995","journal-title":"Prev. Vet. Med."},{"key":"23","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0093-691X(03)00135-3","article-title":"Effect of the amount of body condition loss from the dry to near calving periods on the subsequent body condition change, occurrence of postpartum diseases, metabolic parameters and reproductive performance in Holstein dairy cows","volume":"60","author":"Kim I. H.","year":"2003","journal-title":"Theriogenology"},{"key":"24","doi-asserted-by":"crossref","unstructured":"K\u00f6nyves, L., Szenci, O., Jurkovich, V., Tegzes, L., Tiri\u00e1n, A., Solymosi, N., Gyulay, Gy. and Brydl, E. (2009): Periparturient risk assessment for retained placenta in dairy cows. Acta Vet. Brno (submitted for publication).","DOI":"10.2754\/avb200978010163"},{"key":"25","first-page":"147","article-title":"Determination of net acid-base excretion in the urine of cattle","volume":"15","author":"Kutas F.","year":"1965","journal-title":"Acta Vet. Hung."},{"key":"26","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.prevetmed.2004.09.002","article-title":"Effects of diseases on reproductive performance in Swedish Red and White dairy cattle","volume":"66","author":"Maizon D. O.","year":"2004","journal-title":"Prev. Vet. Med."},{"key":"27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0378-4320(02)00248-8","article-title":"Relationship between endotoxin and prostaglandin (PGE2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis","volume":"76","author":"Mateus L.","year":"2003","journal-title":"Anim. Reprod. Sci."},{"key":"28","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.anireprosci.2006.08.011","article-title":"A herd health approach to dairy cow nutrition and production diseases of the transition cow","volume":"96","author":"Mulligan F. J.","year":"2006","journal-title":"Anim. Reprod. Sci."},{"key":"29","unstructured":"Mulvany, P. (1977): Dairy cow condition scoring. NIRD paper No. 4468."},{"key":"30","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0093-691X(00)00234-X","article-title":"Risk factors for post partum ovarian dysfunction in high producing dairy cows in Belgium: a field study","volume":"53","author":"Opsomer G.","year":"2000","journal-title":"Theriogenology"},{"key":"31","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon I. M.","year":"2006","journal-title":"Theriogenology"},{"key":"32","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.theriogenology.2005.10.004","article-title":"Strategies to improve fertility in the modern dairy cow","volume":"65","author":"Thatcher W. W.","year":"2006","journal-title":"Theriogenology"},{"key":"33","first-page":"459","article-title":"Exact inference for Kendall\u2019s S and Spearman\u2019s Rho with extensions to Fisher\u2019s exact test in r \u00d7 c contingency tables","volume":"3","author":"Valz P. D.","year":"1994","journal-title":"J. Comput. Graph. Stat."},{"key":"34","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1042\/bj0580699","article-title":"A colorimetric method for the estimation of acetoacetate","volume":"58","author":"Walker P. G.","year":"1954","journal-title":"Biochem. J."},{"key":"35","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1210\/endo.142.5.8120","article-title":"Endotoxin inhibits pituitary responsiveness to gonadotropin-releasing hormone","volume":"142","author":"Williams C. Y.","year":"2001","journal-title":"Endocrinology"},{"key":"36","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4142\/jvs.2005.6.1.53","article-title":"Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows","volume":"6","author":"Yeon-Kyung H.","year":"2005","journal-title":"J. Vet. Sci."},{"key":"37","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0093-691X(79)90032-3","article-title":"Variables associated with peripartum traits in dairy cows. Interrelationships among disorders and their effects on intake of feed and on intake on reproductive efficiency","volume":"11","author":"Zamet C. N.","year":"1979","journal-title":"Theriogenology"}],"container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/57\/1\/article-p155.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/avet.57.2009.1.16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T07:00:36Z","timestamp":1684911636000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/avet.57.2009.1.16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,1]]},"references-count":37,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/avet.57.2009.1.16","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,1]]}}}