{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:02:04Z","timestamp":1779912124684,"version":"3.53.1"},"reference-count":27,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,9,1]]},"abstract":"<jats:p><jats:italic>Pasteurella multocida<\/jats:italic>causes infectious diseases in a wide range of animal species. Antimicrobial therapy is still an effective tool for treatment. Generally,<jats:italic>P. multocida<\/jats:italic>isolates are susceptible to most of the widely used commercial antimicrobial agents but their excessive and unjustified use accelerates the emergence of resistant strains. We defined the antimicrobial sensitivity pattern of 56<jats:italic>P. multocida<\/jats:italic>strains isolated from poultry (20) and swine [16<jats:italic>P. multocida<\/jats:italic>toxin (PMT) positive and 20 PMT negative] to 16 widely applied antibiotics (apramycin, cefquinome, chloramphenicol, colistin, doxycycline, enrofloxacin, erythromycin, florfenicol, flumequine, neomycin, oxolinic acid, penicillin, trimethoprim potentiated sulphamethoxazole, sulphonamide compounds, tetracycline, tulathromycin) by the disk diffusion method. The majority of the strains was susceptible to most of the antimicrobial agents tested. However, the resistance to sulphonamides, tetracyclines, first-generation quinolones and aminoglycosides was remarkable, and thus the use of these compounds for the treatment of infection caused by<jats:italic>P. multocida<\/jats:italic>is not recommended. On the other hand, the antimicrobial activity of the classical penicillin, the newer macrolide (tulathromycin), the third-generation fluoroquinolone (enrofloxacin) and the fourth-generation cephalosporin (cefquinome) proved to be satisfactory against this bacterium.<\/jats:p>","DOI":"10.1556\/avet.57.2009.3.2","type":"journal-article","created":{"date-parts":[[2009,7,28]],"date-time":"2009-07-28T03:06:15Z","timestamp":1248750375000},"page":"357-367","source":"Crossref","is-referenced-by-count":37,"title":["Antimicrobial susceptibility of Pasteurella multocida isolated from swine and poultry"],"prefix":"10.1556","volume":"57","author":[{"given":"Bogl\u00e1rka","family":"Sellyei","sequence":"first","affiliation":[{"name":"1 Veterinary Medical Research Institute of the Hungarian Academy of Sciences P.O. 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Vet. Res."},{"key":"7","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.2460\/ajvr.1985.46.07.1490","article-title":"Resistance plasmids of Pasteurella multocida isolated from turkeys","volume":"46","author":"Hirsh D. C.","year":"1985","journal-title":"Am. J. Vet. Res."},{"key":"8","first-page":"422","article-title":"Resistance of bovine and porcine Pasteurella to florfenicol and other antibiotics","volume":"111","author":"H\u00f6rmansdorfer S.","year":"1998","journal-title":"Berl. M\u00fcnch. Tier\u00e4rztl. 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