{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T19:18:24Z","timestamp":1694632704493},"reference-count":19,"publisher":"Akademiai Kiado Zrt.","issue":"Supplement-1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title><jats:p>A myasthenia gravis ritka autoimmun betegs\u00e9g, melyet az akaratlagosan m\u0171k\u00f6d\u0151 izmok k\u00f3ros f\u00e1rad\u00e9konys\u00e1ga jellemez. Ennek oka a m\u0171k\u00f6d\u0151 acetilkolin receptorok sz\u00e1m\u00e1nak cs\u00f6kken\u00e9se az ideg-izom csatlakoz\u00e1sban. A szerz\u0151k visszatekintve vizsg\u00e1lt\u00e1k 1981 \u00e9s 2006 k\u00f6z\u00f6tt 186 beteg myasthenia miatt v\u00e9gzett thymectomia-altat\u00e1ssal nyert tapasztalataikat. M\u0171t\u00e9t ut\u00e1n h\u00e9t beteg ig\u00e9nyelt 24 \u00f3r\u00e1t meghalad\u00f3 g\u00e9pi l\u00e9gz\u00e9st\u00e1mogat\u00e1st, amely egy esetben meghaladta a 7 napot, de seb\u00e9szi hal\u00e1loz\u00e1s nem volt. A m\u0171t\u00e9t el\u0151tt a betegek el\u0151k\u00e9sz\u00edt\u00e9sk\u00e9nt promethazint \u00e9s atropint kaptak. Az altat\u00e1s bevezet\u00e9s\u00e9hez propofolt, ethomidatot, thiopentalt, valamint sevoflurane-t alkalmaztak. Depolariz\u00e1l\u00f3 \u00e9s nem depolariz\u00e1l\u00f3 izomellaz\u00edt\u00f3t nem adtak a m\u0171t\u00e9t sor\u00e1n. A megfelel\u0151 m\u00e9lys\u00e9g\u0171 altat\u00e1st sevoflurane-nal, a f\u00e1jdalommentess\u00e9get kis adag\u00fa opi\u00e1ttal biztos\u00edtott\u00e1k. A betegek 95%-\u00e1t a m\u0171t\u00e9tet k\u00f6vet\u0151en a m\u0171t\u0151asztalon siker\u00fclt extub\u00e1lni. Az intenz\u00edv oszt\u00e1lyon elt\u00f6lt\u00f6tt id\u0151 cs\u00f6kkenthet\u0151, amennyiben a beteg nem ig\u00e9nyel m\u0171t\u00e9t ut\u00e1ni l\u00e9legeztet\u00e9st. F\u00e1jdalomcsillap\u00edt\u00e1shoz nemsteroid gyullad\u00e1sg\u00e1tl\u00f3 k\u00e9sz\u00edtm\u00e9nyt, illetve nalbuphint alkalmaztak. K\u00f6vetkeztet\u00e9s: A myastheni\u00e1s betegek altat\u00e1sa thymectomia sor\u00e1n altat\u00f3g\u00e1zokon alapszik, kis adag\u00fa anticholinerg gy\u00f3gyszerekkel \u00e9s esetleg steroidokkal a l\u00e9gz\u00e9si sz\u00f6v\u0151dm\u00e9nyek megel\u0151zhet\u0151k.<\/jats:p>","DOI":"10.1556\/maseb.61.2008.suppl.9","type":"journal-article","created":{"date-parts":[[2008,5,27]],"date-time":"2008-05-27T01:01:06Z","timestamp":1211850066000},"page":"37-40","source":"Crossref","is-referenced-by-count":1,"title":["Myastheni\u00e1s betegek altat\u00e1sa thymectomia sor\u00e1nr"],"prefix":"10.1556","volume":"61","author":[{"given":"Judit","family":"Hallay","sequence":"first","affiliation":[{"name":"1 Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k, Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum, 4032, Debrecen, M\u00f3ricz Zs. krt. 22."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csaba","family":"Micskei","sequence":"additional","affiliation":[{"name":"1 Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Tansz\u00e9k, Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum, 4032, Debrecen, M\u00f3ricz Zs. krt. 22."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1ndor","family":"Koll\u00e1r","sequence":"additional","affiliation":[{"name":"2 Seb\u00e9szeti Int\u00e9zet, Auguszta Seb\u00e9szeti K\u00f6zpont, Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum, Debrecen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1ndor","family":"Sz. 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