{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T04:23:22Z","timestamp":1648873402212},"reference-count":11,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2009,2,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title>\n        <jats:p>A nyel\u0151cs\u0151seb\u00e9szet \u2013 n\u00e9h\u00e1ny sporadikus pr\u00f3b\u00e1lkoz\u00e1st\u00f3l eltekintve \u2013 alig t\u00f6bb mint 50 \u00e9ves m\u00faltra tekinthet vissza. A mellkasseb\u00e9szet fejl\u0151d\u00e9s\u00e9vel p\u00e1rhuzamosan alakult ki, majd az anaesthesiologia \u00e9s a perioperat\u00edv intenz\u00edv ter\u00e1pia el\u0151rehalad\u00e1s\u00e1val teljesedett ki. A kezdeti id\u0151szakban a nyel\u0151cs\u0151r\u00e1k seb\u00e9szete az als\u00f3 harmadi daganatok \u00e9s az oesophago-gastricus \u00e1tmenetben \u00fcl\u0151, \u00fan. cardiatumorok m\u0171t\u00e9teivel indult. Az 1970-es \u00e9vekre esik a nyel\u0151cs\u0151r\u00e1k miatt v\u00e9gzett m\u0171t\u00e9tek egyre sz\u00e9lesebb k\u00f6rben t\u00f6rt\u00e9n\u0151 elterjed\u00e9se \u00e9s a nyel\u0151cs\u0151-seb\u00e9szeti centrumok kialakul\u00e1sa. Az 1980-as \u00e9vekben a r\u00e9szleges resecti\u00f3kat a szubtot\u00e1lis resecti\u00f3k v\u00e1ltott\u00e1k fel. Az 1990-es \u00e9vek eredm\u00e9nye volt a hypopharynx \u00e9s a nyaki nyel\u0151cs\u0151szakasz tumorainak rutinszer\u0171 kiirt\u00e1sa a megfelel\u0151 centrumokban. \u00c1ltal\u00e1nosan elfogadott\u00e1 v\u00e1lt a rutinszer\u0171 kiterjesztett nyirokcsom\u00f3-elt\u00e1vol\u00edt\u00e1s. Az \u00e9vtized v\u00e9g\u00e9re kikrist\u00e1lyosodott a neoadjuv\u00e1ns radio-kemoter\u00e1pia jelent\u0151s\u00e9ge. Megkezd\u0151d\u00f6tt a thoracoscopos \u00e9s laparoscopos m\u0171t\u00e9tekkel kapcsolatos tapasztalatszerz\u00e9s. A napjainkra kialakult gyakorlat: intraepithelialis \u00e9s csup\u00e1n a muscularis mucosaera terjed\u0151 daganatokn\u00e1l endoscopos mucosectomai vagy m\u00e1s endoscopos kezel\u00e9s az elfogadott a thoracotomia n\u00e9lk\u00fcli nyel\u0151cs\u0151kiirt\u00e1s mellett. Submucosus daganatokn\u00e1l transthoracalisan vagy tranashiatalisan v\u00e9gzett szubtot\u00e1lis resectio \u00e9s 2 mez\u0151s lymphadenectomia a v\u00e1lasztand\u00f3 elj\u00e1r\u00e1s. El\u0151rehaladott T2-es tumorokn\u00e1l kiz\u00e1r\u00f3lag a szubtot\u00e1lis resectio tekinthet\u0151 kurat\u00edv m\u00f3dszernek, a daganat hely\u00e9t\u0151l f\u00fcgg\u0151en 2 vagy 3 mez\u0151s lymphadenectomi\u00e1val kieg\u00e9sz\u00edtve. T3-as \u00e9s T4-es k\u00f6z\u00e9ps\u0151, fels\u0151 harmadi \u00e9s nyaki daganatokn\u00e1l neoadjuv\u00e1ns radio-kemoter\u00e1pia sz\u00fcks\u00e9ges. Csak reszponderekn\u00e9l j\u00f6n sz\u00f3ba resecti\u00f3s m\u0171t\u00e9t kurat\u00edv c\u00e9llal.<\/jats:p>","DOI":"10.1556\/maseb.62.2009.1.2","type":"journal-article","created":{"date-parts":[[2009,2,16]],"date-time":"2009-02-16T02:00:42Z","timestamp":1234749642000},"page":"4-8","source":"Crossref","is-referenced-by-count":0,"title":["A nyel\u0151cs\u0151r\u00e1k seb\u00e9szi kezel\u00e9s\u00e9nek v\u00e1ltoz\u00e1sa az elm\u00falt 50 \u00e9v folyam\u00e1nr"],"prefix":"10.1556","volume":"62","author":[{"given":"J\u00f3zsef","family":"Faller","sequence":"first","affiliation":[{"name":"1 II. sz. Seb\u00e9szeti Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 1125, Budapest, K\u00fatv\u00f6lgyi \u00fat 4."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","volume-title":"Surgical oncology","author":"Bremner CG","year":"2002"},{"key":"2","unstructured":"<i>Faller J:<\/i> Vitatott k\u00e9rd\u00e9sek a nyel\u0151cs\u0151r\u00e1k seb\u00e9szi kezel\u00e9s\u00e9ben. MTA Doktori \u00e9rtekez\u00e9s. 1994"},{"key":"3","unstructured":"<i>Horv\u00e1th \u00d6P:<\/i> \u00daj m\u00f3dszerek a nyel\u0151cs\u0151betegs\u00e9gek seb\u00e9szi kezel\u00e9s\u00e9ben. MTA Doktori \u00e9rtekez\u00e9s, 1992"},{"key":"4","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1016\/S0003-4975(01)03167-8","article-title":"Larynx preserving pharyngo-esophagectomy after chemoradiation in the treatment of cancer of the pharyngo-esophageal junction","volume":"72","author":"Horv\u00e1th \u00d6P","year":"2001","journal-title":"Ann Thor Surg"},{"key":"5","first-page":"333","article-title":"A neoadjuvans kezel\u00e9s eredm\u00e9nyezte fejl\u0151d\u00e9s a gasztrointesztin\u00e1lis daganatok seb\u00e9szet\u00e9ben","volume":"59","author":"Horv\u00e1th \u00d6P","year":"2006","journal-title":"Magy Seb"},{"key":"6","unstructured":"<i>Kiss J:<\/i> Szeml\u00e9let-v\u00e1ltoz\u00e1sok a nyel\u0151cs\u0151 \u00e9s kiterjesztett gyomorseb\u00e9szetben. MTA doktori \u00e9rtekez\u00e9s. 2003"},{"key":"7","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/00000658-199211000-00010","article-title":"Surgical strategies in esophageal carcinoma with emphasis on radical lymphadenectomy","volume":"216","author":"Lerut T","year":"1992","journal-title":"Ann Surg"},{"key":"8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.1442-2050.2001.00162.x","article-title":"Role of laparoscopy and thoracoscopy in thetratment of esophageal carcinoma","volume":"14","author":"Oelschlager BK","year":"2001","journal-title":"Dis Esoph"},{"key":"9","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1442-2050.2001.00163.x","article-title":"Current status of surgery for Carcinoma of the hypopharynx and cervical esophagus","volume":"14","author":"Peracchia A","year":"2001","journal-title":"Dis Esoph"},{"key":"10","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/00000658-200009000-00007","article-title":"Adenocarcinoma of the esiphagogastric junction. Results of surgical therapy based on anatomical\/topographic classification in 1002 consecutive patients","volume":"232","author":"Siewert JR","year":"2000","journal-title":"Ann Surg"},{"key":"11","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1007\/s00268-005-0010-4","article-title":"Multimodal treatment of gastrointestnal tract tumors: Consequences for surgery","volume":"29","author":"Siewert JR","year":"2005","journal-title":"World J Surg"}],"container-title":["Magyar Seb\u00e9szet"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/62\/1\/article-p4.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/maseb.62.2009.1.2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T09:58:37Z","timestamp":1590141517000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/maseb.62.2009.1.2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,1]]},"references-count":11,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/maseb.62.2009.1.2","relation":{},"ISSN":["0025-0295","1789-4301"],"issn-type":[{"value":"0025-0295","type":"print"},{"value":"1789-4301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,1]]}}}