{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T23:12:55Z","timestamp":1649113975277},"reference-count":30,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2011,8,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title>\n        <jats:p>\n          <jats:italic>Bevezet\u00e9s\/c\u00e9lkit\u0171z\u00e9s:<\/jats:italic> Annak t\u00e9nye, hogy a v\u00e9konyb\u00e9l rendk\u00edv\u00fcl \u00e9rz\u00e9keny az ischaemi\u00e1s\/reperfusi\u00f3s k\u00e1rosod\u00e1sokra, ind\u00edtotta el azokat az \u00f6sszehasonl\u00edt\u00f3 vizsg\u00e1latokat, ahol meleg \u00e9s hideg ischaemia hat\u00e1s\u00e1ra a b\u00e9l sz\u00f6veti strukt\u00far\u00e1j\u00e1ban bek\u00f6vetkez\u0151 v\u00e1ltoz\u00e1sokat tanulm\u00e1nyoztuk differenci\u00e1l p\u00e1szt\u00e1z\u00f3 kalorimetri\u00e1s (DSC) m\u00f3dszerrel. <jats:italic>Anyag \u00e9s m\u00f3dszerek:<\/jats:italic> Meleg \u00e9s hideg ischaemi\u00e1s csoportokat hoztunk l\u00e9tre 1, 3 \u00e9s 6 \u00f3r\u00e1s ischaemi\u00e1s id\u0151kkel Wistar-patk\u00e1nyokon (<jats:italic>n<\/jats:italic> = 30). A b\u00e9lsz\u00f6vetb\u0151l mint\u00e1t vett\u00fcnk a laparotomia ut\u00e1n (kontroll) \u00e9s az ischaemi\u00e1s peri\u00f3dusok v\u00e9g\u00e9n. A DSC m\u00e9r\u00e9seket a b\u00e9l mucosa- \u00e9s izomr\u00e9teg\u00e9n, valamint a teljes b\u00e9lfal mint\u00e1iban v\u00e9gezt\u00fck el. <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A DSC adatok meger\u0151s\u00edtett\u00e9k, hogy a meleg ischaemia idej\u00e9nek n\u00f6vel\u00e9se fokozza a mucosa- \u00e9s izomr\u00e9teg k\u00e1rosod\u00e1s\u00e1t. Az \u00e1talakul\u00e1si h\u0151m\u00e9rs\u00e9klet \u00e9s a kalorimetri\u00e1s entalpia eredm\u00e9nyek alapj\u00e1n \u00fagy t\u0171nik, hogy a k\u00e1rosod\u00e1s kisebb m\u00e9rt\u00e9k\u0171 University of Wisconsin oldatban t\u00f6rt\u00e9n\u0151 hideg t\u00e1rol\u00e1s eset\u00e9n, de a b\u00e9lsz\u00f6vet valamennyi r\u00e9teg\u00e9ben bek\u00f6vetkez\u0151 termikus destructio jelzi, hogy jelent\u0151s k\u00e1rosod\u00e1s \u00e1ll fenn. <jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic> Jelen munk\u00e1nkban DSC technik\u00e1val kvantitat\u00edv m\u00f3don tudtuk kimutatni az ischaemia hat\u00e1s\u00e1ra a b\u00e9lsz\u00f6vetben bek\u00f6vetkez\u0151 struktur\u00e1lis k\u00e1rosod\u00e1sokat. Ez a termoanalitikai m\u00f3dszer alkalmasnak t\u0171nik a j\u00f6v\u0151ben tov\u00e1bbi k\u00fcl\u00f6nb\u00f6z\u0151 stresszmodellek vizsg\u00e1lat\u00e1ra.<\/jats:p>","DOI":"10.1556\/maseb.64.2011.4.5","type":"journal-article","created":{"date-parts":[[2011,8,13]],"date-time":"2011-08-13T01:10:43Z","timestamp":1313197843000},"page":"207-212","source":"Crossref","is-referenced-by-count":0,"title":["A v\u00e9konyb\u00e9l meleg \u00e9s hideg ischaemi\u00e1s k\u00e1rosod\u00e1s\u00e1nak kimutat\u00e1sa differenci\u00e1l p\u00e1szt\u00e1z\u00f3 kalorimetri\u00e1s vizsg\u00e1lattal"],"prefix":"10.1556","volume":"64","author":[{"given":"Kl\u00e1ra","family":"Nedvig","sequence":"first","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Seb\u00e9szeti Oszt\u00e1ly, Zala Megyei K\u00f3rh\u00e1z, 8900, Zalaegerszeg, Zr\u00ednyi u. 1."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Zapf","sequence":"additional","affiliation":[{"name":"2 Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Fekecs","sequence":"additional","affiliation":[{"name":"3 B\u0151r-, Nemik\u00f3rtani \u00e9s Onkodermatol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1365-2036.2005.02269.x","article-title":"Review article: diagnosis and management of mesenteric ischaemia with an emphasis on pharmacotherapy","volume":"21","author":"Kozuch PL","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"key":"2","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1023\/B:DDAS.0000042232.98927.91","article-title":"Ischemia-reperfusion injury of the intestine and protective strategies against injury","volume":"49","author":"Mallick IH","year":"2004","journal-title":"Dig Dis Sci"},{"key":"3","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1023\/A:1018899927786","article-title":"Intestinal motility during hypoxia and reoxygenation in vitro","volume":"42","author":"Bielefeldt K","year":"1997","journal-title":"Dig Dis Sci"},{"key":"4","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1067\/msy.2002.129910","article-title":"The effects of preconditioning on the oxidative stress in small bowel autotransplantation","volume":"132","author":"Ferencz A","year":"2002","journal-title":"Surgery"},{"key":"5","volume-title":"Proceedings of the 45th Congress of the European Society for Surgical Research","author":"Nedvig K","year":"2010"},{"key":"6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.transproceed.2008.08.149","article-title":"Influence of pituitary adenylate cyclase-activating polypeptide on the activation of mitogen activated protein kinases following small bowel cold preservation","volume":"41","author":"Ferencz A","year":"2009","journal-title":"Transplant Proc"},{"key":"7","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/j.1600-6143.2004.00541.x","article-title":"Ameliorating small bowel injury using a cavitary two-layer preservation method with perfluorocarbon and a nutrient-rich solution","volume":"4","author":"Salehi P","year":"2004","journal-title":"Am J Transplant"},{"key":"8","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1016\/S0041-1345(99)00265-1","article-title":"Preservation solutions for transplantation","volume":"31","author":"M\u00fclbacher F","year":"1999","journal-title":"Transplant Proc"},{"key":"9","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/S0041-1345(00)01238-0","article-title":"An evaluation of methods for grading histologic injury following ischemia\/reperfusion of the small bowel","volume":"32","author":"Quaedackers JSLT","year":"2000","journal-title":"Transplant Proc"},{"key":"10","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.2174\/0929867054546564","article-title":"Differential scanning calorimetry in life science: thermodynamics, stability, molecular recognition and application in drug design","volume":"12","author":"Bruylants G","year":"2005","journal-title":"Curr Med Chem"},{"key":"11","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s10973-005-7434-9","article-title":"Differential scanning calorimetric examination of the oesophagus after two different self-expandable stents implantation. 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