{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T12:39:27Z","timestamp":1648643967345},"reference-count":23,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2012,8,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title><jats:p><jats:italic>Bevezet\u00e9s\/C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>K\u00eds\u00e9rleteink c\u00e9lja a periosteum mikrokering\u00e9si v\u00e1ltoz\u00e1sainak felt\u00e9rk\u00e9pez\u00e9se, valamint a vel\u0151\u0171rfelf\u00far\u00e1s \u00e1ltal okozott periostealis mikro\u00e9r-reakci\u00f3k modellez\u00e9se, id\u0151beli v\u00e1ltoz\u00e1suk megismer\u00e9se volt. Tov\u00e1bbi vizsg\u00e1latainkban jellemezt\u00fck \u00e9s \u00f6sszehasonl\u00edtottuk a hum\u00e1n cs\u00edp\u0151\u00edz\u00fcleti endoprotetik\u00e1ban haszn\u00e1latos anyagok mikrokering\u00e9si hat\u00e1sait a csonth\u00e1rty\u00e1ban.<jats:italic>Anyag \u00e9s m\u00f3dszer:<\/jats:italic>H\u00edm Wistar-patk\u00e1nyok jobb oldali tibi\u00e1j\u00e1ba endomedullaris tit\u00e1n-, ac\u00e9l\u00f6tv\u00f6zet, illetve polietil\u00e9n implant\u00e1tumot helyezt\u00fcnk mikroseb\u00e9szeti m\u00f3dszerrel. Intravitalis videomikroszk\u00f3p seg\u00edts\u00e9g\u00e9vel vizsg\u00e1ltuk a tibia anteromedialis \u00e9s anterolateralis felsz\u00edn\u00e9n a periosteum \u00e9rstrukt\u00far\u00e1j\u00e1t (\u00f6ssz-\u00e9rdenzit\u00e1s, kapill\u00e1risok ar\u00e1nya), valamint mikroszk\u00f3pos mechanikai teszt seg\u00edts\u00e9g\u00e9vel az implant\u00e1tumok stabilit\u00e1s\u00e1t. Kontrollcsoportban vizsg\u00e1ltuk a vel\u0151\u0171rfelf\u00far\u00e1s hat\u00e1s\u00e1t a periostealis \u00e9rstrukt\u00fara v\u00e1ltoz\u00e1saira a m\u0171t\u00e9t ut\u00e1n 6 \u00e9s 12 h\u00e9ttel.<jats:italic>Eredm\u00e9nyek:<\/jats:italic>A vel\u0151\u0171r felf\u00far\u00e1sa \u00f6nmag\u00e1ban szignifik\u00e1nsan n\u00f6velte az anteromedialis periosteum \u00e9rdenzit\u00e1s\u00e1t, valamint a kapill\u00e1risok s\u0171r\u0171s\u00e9g\u00e9t a beavatkoz\u00e1s ut\u00e1n 12 h\u00e9ttel. Mindh\u00e1rom implant\u00e1tum fokozta az \u00e9rdenzit\u00e1st az anteromedialis oldalon, az anterolateralis oldalon azonban csak a polietil\u00e9n implant\u00e1tum eset\u00e9ben \u00e9szlelt\u00fcnk jelent\u0151s periostealis kapill\u00e1ris- \u00e9s \u00e9rdenzit\u00e1s-fokoz\u00f3d\u00e1st. A tit\u00e1n- \u00e9s ac\u00e9limplant\u00e1tumokkal szemben a polietil\u00e9nb\u0151l k\u00e9sz\u00fclt implant\u00e1tum nem v\u00e1ltott ki \u00e9rdemi osseointegr\u00e1ci\u00f3t.<jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic>A patk\u00e1ny tibiavel\u0151\u0171r felf\u00far\u00e1sa kompenz\u00e1ci\u00f3s \u00e9r\u00fajdonk\u00e9pz\u0151d\u00e9st eredm\u00e9nyez, amely megn\u00f6veli a periostealis \u00e9rdenzit\u00e1st 12 h\u00e9ttel a beavatkoz\u00e1s ut\u00e1n. A hossz\u00fa cs\u00f6ves csontok endostealis mikrokering\u00e9s\u00e9nek roncsol\u00e1sa \u00e1ltal okozott periostealis \u00e9rreakci\u00f3t a teljes osseointegr\u00e1ci\u00f3val j\u00e1r\u00f3 implant\u00e1tumok nem befoly\u00e1solj\u00e1k l\u00e9nyegesen, m\u00edg az osseointegr\u00e1ci\u00f3ra k\u00e9ptelen implant\u00e1tum nagyon jelent\u0151s \u00e9r\u00fajdonk\u00e9pz\u0151d\u00e9st okozhat.<\/jats:p>","DOI":"10.1556\/maseb.65.2012.4.2","type":"journal-article","created":{"date-parts":[[2012,9,2]],"date-time":"2012-09-02T07:41:39Z","timestamp":1346571699000},"page":"178-183","source":"Crossref","is-referenced-by-count":0,"title":["A csont mikrokering\u00e9si v\u00e1ltoz\u00e1sainak k\u00eds\u00e9rletes vizsg\u00e1lati lehet\u0151s\u00e9gei"],"prefix":"10.1556","volume":"65","author":[{"given":"Ferenc","family":"Greksa","sequence":"first","affiliation":[{"name":"1 Ortop\u00e9diai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u00e1lm\u00e1n","family":"T\u00f3th","sequence":"additional","affiliation":[{"name":"1 Ortop\u00e9diai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mih\u00e1ly","family":"Boros","sequence":"additional","affiliation":[{"name":"2 Seb\u00e9szeti M\u0171t\u00e9ttani Int\u00e9zet, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 6720, Szeged, P\u00e9csi u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"2 Seb\u00e9szeti M\u0171t\u00e9ttani Int\u00e9zet, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 6720, Szeged, P\u00e9csi u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00003086-197411000-00004","article-title":"The role of periosteal blood supply in the healing of fractures of the tibia","volume":"105","author":"Macnab I","year":"1974","journal-title":"Clin Orthop"},{"key":"2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.2106\/00004623-196850040-00001","article-title":"Microangiography in bone healing. II. displaced closed fractures","volume":"50","author":"Rhinelander FW","year":"1968","journal-title":"J Bone Joint Surg (Am)"},{"key":"3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00003086-197411000-00003","article-title":"Blood supply and the rate of healing of tibial fractures","volume":"105","author":"Trueta J","year":"1974","journal-title":"Clin Orthop"},{"key":"4","volume-title":"The science and practice of intramedullary nailing","author":"Rhinelander FW","year":"1987"},{"key":"5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1302\/0301-620X.37B3.492","article-title":"Vascular changes caused by the K\u00fcntscher type of nailing","volume":"37","author":"Trueta J","year":"1955","journal-title":"J Bone Joint Surg (Br)"},{"key":"6","first-page":"1362","article-title":"The effect of intramedullary nailing on the blood supply of the diaphysis of long bones in mature dogs","volume":"46","author":"Gustilo RB","year":"1964","journal-title":"J Bone Joint Surg (Am)"},{"key":"7","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0030-5898(20)31672-2","article-title":"Management of soft tissue wounds associated with type III open fractures","volume":"22","author":"Esterhai JL","year":"1991","journal-title":"Ortop Clin North Am"},{"key":"8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s002239900080","article-title":"Effect of periosteal stripping on cortical bone perfusion: a laser-Doppler study in sheep","volume":"59","author":"Kowalski MJ","year":"1996","journal-title":"Calcif Tissue Int"},{"key":"9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3109\/17453679809117623","article-title":"Effects of lesion between bone, periosteum and muscle on fracture healing in rats","volume":"69","author":"Utvag SE","year":"1998","journal-title":"Acta Orthop Scand"},{"key":"10","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.2106\/00004623-197052070-00013","article-title":"Intracortical circulation after intramedullary reaming with reduction of pressure in the medullary cavity: a microangiographic study on the rabbit tibia","volume":"52","author":"Danckwardt-Lilliestr\u00f6m G","year":"1970","journal-title":"J Bone Joint Surg (Am)"},{"key":"11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.2106\/00004623-197759030-00015","article-title":"The effect of fixation with intramedullary rods and plates on fracture- site blood flow and bone remodeling in dogs","volume":"59","author":"Barron SE","year":"1977","journal-title":"J Bone Joint Surg (Am)"},{"key":"12","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0021-9290(77)90046-X","article-title":"Effect of compression and cyclic loading on fracture healing \u2013 a quantitative biomechanical study","volume":"10","author":"White AA","year":"1977","journal-title":"J Biomech"},{"key":"13","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/0142-9612(96)84676-X","article-title":"Periosteal and endosteal reaction to reaming and nailing: the possible role of revascularization on the endosteal anchorage of cementless stems","volume":"17","author":"Pazzaglia UE","year":"1996","journal-title":"Biomaterials"},{"key":"14","doi-asserted-by":"crossref","unstructured":"<i>Greksa F, T\u00f3th K, Boros M, Szab\u00f3 A:<\/i> Periosteal microvascular reorganization after tibial reaming and intramedullary nailing in rats. J Orthop Sci 2012 Apr 5.; Epub ahead of print","DOI":"10.1007\/s00776-012-0222-z"},{"key":"15","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1302\/0301-620X.77B3.7744943","article-title":"The acute vascular response to intramedullary reaming. Microsphere estimation of blood flow in the intact ovine tibia","volume":"77","author":"Reichert IL","year":"1995","journal-title":"J Bone Joint Surg (Br)"},{"key":"16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00003086-198305000-00015","article-title":"Aseptic loosening of hip prostheses: a histological and enzyme histochemical study","volume":"175","author":"Linder L","year":"1983","journal-title":"Clin Orthop"},{"key":"17","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s00776-005-0896-6","article-title":"Analysis of polyethylene particles isolated from periprosthetic tissue of loosened arthroplasty and comparison with radiographic appearance","volume":"10","author":"Koseki H","year":"2005","journal-title":"J Orthop Sci"},{"key":"18","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/s00776-008-1317-4","article-title":"Cementless total hip replacement: past, present, and future","volume":"14","author":"Yamada H","year":"2009","journal-title":"J Orthop Sci"},{"key":"19","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1177\/014107689008301206","article-title":"Bone scan appearances after uncemented hip replacement","volume":"83","author":"Ashbrooke AB","year":"1990","journal-title":"J Royal Society of Med"},{"key":"20","first-page":"62","article-title":"Nuclear arthrography: combined scintigraphic and radiographic procedure for diagnosis of total hip prosthesis loosening","volume":"37","author":"Oyen WJ","year":"1996","journal-title":"J Nucl Med"},{"key":"21","first-page":"438","article-title":"A revision for the hip joint","volume":"18","author":"Wagner H","year":"1989","journal-title":"Orthopaede"},{"key":"22","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.clinbiomech.2006.02.002","article-title":"Biomechanical comparison of extended trochanteric osteotomy and slot osteotomy for femoral component revision in total hip arthroplasty","volume":"22","author":"Khanna G","year":"2007","journal-title":"Clin Biomech"},{"key":"23","first-page":"177","article-title":"KR cs\u00edp\u0151prot\u00e9zis-sz\u00e1rral szerzett tapasztalataink ki\u00e9rt\u00e9kel\u00e9se k\u00f6z\u00e9pt\u00e1v\u00fa ut\u00e1nk\u00f6vet\u00e9ssel","volume":"42","author":"Sass L","year":"1999","journal-title":"Magyar Traumatol\u00f3gia, Ortop\u00e9dia, K\u00e9zseb\u00e9szet, Plasztikai Seb\u00e9szet"}],"container-title":["Magyar Seb\u00e9szet"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/65\/4\/article-p178.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/maseb.65.2012.4.2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T02:35:13Z","timestamp":1643337313000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/maseb.65.2012.4.2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,1]]},"references-count":23,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1556\/maseb.65.2012.4.2","relation":{},"ISSN":["0025-0295","1789-4301"],"issn-type":[{"value":"0025-0295","type":"print"},{"value":"1789-4301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,1]]}}}