{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:18:00Z","timestamp":1745468280620,"version":"3.40.4"},"reference-count":20,"publisher":"Akademiai Kiado Zrt.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2012,12,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title><jats:p><jats:italic>H\u00e1tt\u00e9r:<\/jats:italic>Az alapadatok hi\u00e1nya az egyik f\u0151 oka annak, hogy ellentmond\u00e1sosak a marihu\u00e1na \u00e9s a kr\u00f3nikus t\u00fcd\u0151s\u00e9r\u00fcl\u00e9s k\u00f6z\u00f6tti kapcsolat meg\u00edt\u00e9l\u00e9se. Anekdotikus esetbesz\u00e1mol\u00f3k szerint a fiatal marihu\u00e1nasz\u00edv\u00f3k k\u00f6r\u00e9ben a spont\u00e1n primer pneumothorax (SPP) gyakoris\u00e1ga nagyobb, s ez oki kapcsolatot vet fel.<jats:italic>Betegek \u00e9s m\u00f3dszer:<\/jats:italic>Retrospekt\u00edve dolgoztuk fel az SPP miatt az elm\u00falt k\u00e9t \u00e9vben klinik\u00e1nkon kezelt 20 beteg adatait. Vizsg\u00e1ltuk a demogr\u00e1fia \u00e9s a kezel\u00e9si m\u00f3d szerinti inform\u00e1ci\u00f3kat, figyelt\u00fck a kimenetelt. Khi-n\u00e9gyzet-pr\u00f3b\u00e1t, Mann\u2013Whitney-tesztet \u00e9s Fisher-tesztet haszn\u00e1ltunk statisztikai anal\u00edzisre. Nem szerinti megoszl\u00e1s: 16 f\u00e9rfi, 4 n\u0151, \u00e1tlag\u00e9letkor 23,95 \u00b1 4,57 \u00e9v: min. 18 \u00e9v, max. 32 \u00e9v. \u00d6nbevall\u00e1s szerint 13\/20 rendszeres cannabishaszn\u00e1l\u00f3 (CH), fogyaszt\u00f3 volt, k\u00f6z\u00fcl\u00fck 11 f\u00e9rfi, 2 n\u0151, \u00e1tlag\u00e9letkor 24,54 \u00b1 4,77 \u00e9v. \u00d6sszesen 7\/20 betegnek volt m\u00e1r kor\u00e1bban pneumothoraxa.<jats:italic>Eredm\u00e9nyek:<\/jats:italic>A nem cannabishaszn\u00e1l\u00f3 (NCH) csoportban 3\/7 beteg csup\u00e1n mell\u0171ri drainage-ra is gy\u00f3gyult. 4\/7 NCH betegn\u00e9l \u201enagy\u201d m\u0171t\u00e9tre volt sz\u00fcks\u00e9g, mind a n\u00e9gy betegn\u00e9l VATS-ot v\u00e9gezt\u00fcnk. A CH csoportban 4\/13 beteg csak mellkasi drainage-ra szorult. 9\/13 p\u00e1ciens mellkasnyit\u00e1st ig\u00e9nyelt (8 VATS, 1 nyitott m\u0171t\u00e9t). R\u00f6videbb drainage-hosszot \u00e9szlelt\u00fcnk a NCH csoportban (4,00 \u00b1 1,00 nap NCH vs. 4,5 \u00b1 1,73 nap CH,<jats:italic>p<\/jats:italic>= 0,651). Nagyobb volt a nem megfelel\u0151 t\u00fcd\u0151t\u00e1gul\u00e1s vagy tart\u00f3s \u00e1tereszt\u00e9s miatti operat\u00edv esetek ar\u00e1nya a cannabishaszn\u00e1l\u00f3 csoportban (69,23% vs. NCH 57,14%,<jats:italic>p<\/jats:italic>= 0,651). Mellkasi drainage ut\u00e1n 2 betegn\u00e9l \u00e9szlelt\u00fcnk recid\u00edv\u00e1t, egy CH, egy NCH betegn\u00e9l, mindkett\u0151 VATS m\u0171t\u00e9tet k\u00f6vet\u0151en sz\u00f6v\u0151dm\u00e9nymentesen gy\u00f3gyult. A CH csoportban magasabb a recid\u00edv l\u00e9gmell ar\u00e1nya (odds ratio 1,56). A sz\u00f6vettani vizsg\u00e1lat sor\u00e1n nem tal\u00e1ltunk l\u00e9nyeges elt\u00e9r\u00e9st a k\u00e9t csoportban, az operat\u00edv esetekb\u0151l 11\/13 betegn\u00e9l igazol\u00f3dott emphysaema pulmonum. A megyei demogr\u00e1fiai \u00e9s klinikai adatokkal egybevetve a klinikai el\u0151fordul\u00e1st, a marihu\u00e1nahaszn\u00e1l\u00f3k k\u00f6zt magasabb a l\u00e9gmell kock\u00e1zata (odds ratio 3,86).<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>A kis mintam\u00e9ret ellen\u00e9re \u00fagy l\u00e1tszik, van kapcsolat a marihu\u00e1nahaszn\u00e1lat \u00e9s a SPP k\u00f6zt. Azt nem tudjuk, hogy a cannabis k\u00f6zvetlen oka-e a l\u00e9gmell kialakul\u00e1s\u00e1nak, vagy csak s\u00falyosb\u00edt egy alapvet\u0151en megl\u00e9v\u0151 gyenge t\u00fcd\u0151parenchyma-\u00e1llapotot. A fiatalok e kock\u00e1zatos csoportj\u00e1ban agressz\u00edvebb seb\u00e9szi kezel\u00e9st aj\u00e1nlunk, figyelembe v\u00e9ve a m\u00f6g\u00f6ttes t\u00fcd\u0151parenchyma-k\u00e1rosod\u00e1st \u00e9s a magasabb recid\u00edvaar\u00e1nyt.<\/jats:p>","DOI":"10.1556\/maseb.65.2012.6.5","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T02:25:50Z","timestamp":1355192750000},"page":"421-425","source":"Crossref","is-referenced-by-count":0,"title":["A spont\u00e1n primer l\u00e9gmell aetiopathogenesis\u00e9hez. Marihu\u00e1na: ok vagy b\u0171nbak?"],"prefix":"10.1556","volume":"65","author":[{"given":"L\u00e1szl\u00f3","family":"Jakab","sequence":"first","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 7624, P\u00e9cs, R\u00e1k\u00f3czi \u00fat 2."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zal\u00e1n","family":"Sz\u00e1nt\u00f3","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 7624, P\u00e9cs, R\u00e1k\u00f3czi \u00fat 2."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Benk\u0151","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, 7624, P\u00e9cs, R\u00e1k\u00f3czi \u00fat 2."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Szalai","sequence":"additional","affiliation":[{"name":"2 T\u00fcd\u0151gy\u00f3gy\u00e1szati Oszt\u00e1ly, Karolina K\u00f3rh\u00e1z, Mosonmagyar\u00f3v\u00e1r"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"P\u00f3t\u00f3","sequence":"additional","affiliation":[{"name":"3 Bioanalitikai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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