{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T08:25:36Z","timestamp":1649147136781},"reference-count":15,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2014,8,1]]},"abstract":"<jats:title>Absztrakt<\/jats:title><jats:p><jats:italic>Esetismertet\u00e9s:<\/jats:italic>A 25 \u00e9ves primipara, terhess\u00e9g\u00e9nek 32. het\u00e9ben, \u00f6nvizsg\u00e1lat sor\u00e1n a bal eml\u0151 k\u00fcls\u0151-fels\u0151 negyed\u00e9ben csom\u00f3t \u00e9szlelt. A komplex eml\u0151vizsg\u00e1lat 4 cm \u00e1tm\u00e9r\u0151j\u0171 ter\u00fcleten meszesed\u00e9st \u00edrt le. A finomt\u0171-biopsia malignus ductalis karakter\u0171 sejteket, \u201eC5\u201d kateg\u00f3ri\u00e1t, a core-biopsia III-as gradus\u00fa, invasiv ductalis carcinom\u00e1t v\u00e9lem\u00e9nyezett (\u201eB5b\u201d), t\u00e1voli disseminatio nem igazol\u00f3dott. A terhess\u00e9g termin\u00e1l\u00e1s\u00e1t k\u00f6vet\u0151en az elv\u00e1ltoz\u00e1s sz\u00e9les excisi\u00f3j\u00e1t v\u00e9gezt\u00fck sentinelnyirokcsom\u00f3-biopsi\u00e1val, amelynek pozitivit\u00e1sa miatt axillaris blockdissectio t\u00f6rt\u00e9nt. A seb\u00e9szi kezel\u00e9st adjuv\u00e1ns onkol\u00f3giai kezel\u00e9s k\u00f6vette. A k\u00e9s\u0151bbiekben a jobb inguinalis r\u00e9gi\u00f3ban l\u00e9v\u0151 angiomyxoma jelent meg, amelyet in toto excindaltunk.<jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic>A terhess\u00e9ggel \u00f6sszef\u00fcgg\u0151 malignus betegs\u00e9gek incidenci\u00e1ja emelkedik, amelyek k\u00f6z\u00fcl az eml\u0151daganatok kit\u00fcntetett helyen \u00e1llnak. Terhess\u00e9gasszoci\u00e1lt eml\u0151daganatr\u00f3l akkor besz\u00e9l\u00fcnk, amennyiben annak diagn\u00f3zisa a graviditas alatt vagy az azt k\u00f6vet\u0151 els\u0151 \u00e9vben t\u00f6rt\u00e9nik. A terhess\u00e9ggel j\u00e1r\u00f3 \u00e9lettani v\u00e1ltoz\u00e1sok miatt a betegs\u00e9g felismer\u00e9se nehezebb\u00e9 v\u00e1lik, s ennek k\u00f6vetkezt\u00e9ben sokszor ezek a betegek elk\u00e9sve ker\u00fclnek l\u00e1t\u00f3k\u00f6r\u00fcnkbe. A betegs\u00e9g ter\u00e1pi\u00e1ja \u00f6sszetett, mivel az anya kezel\u00e9se mellett a magzat biztons\u00e1g\u00e1ra is nagy hangs\u00falyt kell fektetni \u2013 mindez a t\u00e1rsszakm\u00e1k fokozott egy\u00fcttm\u0171k\u00f6d\u00e9s\u00e9t ig\u00e9nyli. A kezel\u00e9si strat\u00e9gia az egyes trimeszterekben elt\u00e9r\u0151. Seb\u00e9szi kezel\u00e9s a terhess\u00e9g b\u00e1rmely szak\u00e1ban v\u00e9gezhet\u0151. A sug\u00e1rkezel\u00e9sr\u0151l, magzatk\u00e1ros\u00edt\u00f3 hat\u00e1sa miatt, megoszlanak a v\u00e9lem\u00e9nyek. A kemoter\u00e1pia a terhess\u00e9g m\u00e1sodik \u00e9s harmadik harmad\u00e1ban megengedett. Beteg\u00fcnk k\u00f6zel h\u00e1rom \u00e9vvel a m\u0171t\u00e9tet k\u00f6vet\u0151en panaszmentes, fi\u00fagyermeke eg\u00e9szs\u00e9ges.<\/jats:p>","DOI":"10.1556\/maseb.67.2014.4.5","type":"journal-article","created":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T01:29:43Z","timestamp":1408066183000},"page":"268-270","source":"Crossref","is-referenced-by-count":0,"title":["A terhess\u00e9ggel \u00f6sszef\u00fcgg\u0151 eml\u0151daganatok kezel\u00e9se"],"prefix":"10.1556","volume":"67","author":[{"given":"J\u00e1nos","family":"Tajti Jr.","sequence":"first","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, 6720, Szeged, Sz\u0151kefalvi-Nagy u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"Pieler","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, 6720, Szeged, Sz\u0151kefalvi-Nagy u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"Simonka","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, 6720, Szeged, Sz\u0151kefalvi-Nagy u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"Paszt","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, 6720, Szeged, Sz\u0151kefalvi-Nagy u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"L\u00e1z\u00e1r","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, 6720, Szeged, Sz\u0151kefalvi-Nagy u. 6."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"1","volume-title":"Eml\u0151- \u00e9s n\u0151gy\u00f3gy\u00e1szati onkol\u00f3gia","year":"2012"},{"key":"2","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ejso.2008.01.029","article-title":"Breast cancer during pregnancy: a mini-review","volume":"34","author":"Navrozoglou I","year":"2008","journal-title":"Eur J Surg Oncol"},{"key":"3","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.ejso.2008.04.010","article-title":"Pregnancy associated breast cancer","volume":"35","author":"Garcia-Manero M","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"4","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/0029-7844(95)00470-X","article-title":"Breast cancer during pregnancy: quantifying the risk of treatment delay","volume":"87","author":"Nettleton J","year":"1996","journal-title":"Obstet Gynecol"},{"key":"5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1001\/archsurg.138.1.91","article-title":"Breast cancer in pregnancy: a literature review","volume":"138","author":"Woo JC","year":"2003","journal-title":"Arch Surg"},{"key":"6","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.ctrv.2005.04.010","article-title":"The pregnant mother with breast cancer: diagnostic and therapeutic management","volume":"31","author":"Pavlidis N","year":"2005","journal-title":"Cancer Treat Rev"},{"key":"7","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1016\/j.ejca.2010.09.010","article-title":"Breast cancer in pregnancy: recommendations of an international consensus meeting","volume":"46","author":"Amant F","year":"2010","journal-title":"Eur J Cancer"},{"key":"8","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1556\/OH.2013.29771","article-title":"Sentinel lymph node biopsy in pregnancy-associated breast cancer","volume":"154","author":"Matrai Z","year":"2013","journal-title":"Orv Hetil"},{"key":"9","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.amjsurg.2009.03.013","article-title":"Pharmacokinetics of methylene blue dye for lymphatic mapping in breast cancer-implications for use in pregnancy","volume":"201","author":"Pruthi S","year":"2011","journal-title":"Am J Surg"},{"key":"10","unstructured":"Mastectomy or lumpectomy? 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