{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T22:12:35Z","timestamp":1649110355965},"reference-count":25,"publisher":"Akademiai Kiado Zrt.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"abstract":"<jats:p>A rectum k\u00f6z\u00e9ps\u0151 \u00e9s als\u00f3 harmada v\u00e1logatott daganatainak ell\u00e1t\u00e1s\u00e1ra kifejlesztett transanalis endoscopos mikroseb\u00e9szeti (TEM) elj\u00e1r\u00e1s alacsony recid\u00edva- \u00e9s sz\u00f6v\u0151dm\u00e9nyr\u00e1t\u00e1j\u00fa, \u00edgy a hagyom\u00e1nyos m\u0171t\u00e9ti technik\u00e1k alternat\u00edv\u00e1ja lehet, ha az onkol\u00f3giai radikalit\u00e1s szempontj\u00e1b\u00f3l nem jelent kompromisszumot. A TEM-elj\u00e1r\u00e1s 2013 \u0151sz\u00e9t\u0151l \u00e9rhet\u0151 el \u2013 Magyarorsz\u00e1gon m\u00e1sodik centrumk\u00e9nt, de jelenleg a legkorszer\u0171bb felszerelts\u00e9g\u0171 \u2212 a Semmelweis Egyetem I. Sz. Seb\u00e9szeti Klinik\u00e1j\u00e1n. Jelen vizsg\u00e1latunkban c\u00e9lul t\u0171zt\u00fck ki, hogy az ut\u00f3bbi egy \u00e9v klinikopatol\u00f3giai adatait elemezz\u00fck. 2013. szeptember \u00e9s 2014. szeptember k\u00f6z\u00f6tt TEM-technik\u00e1val oper\u00e1lt betegek adatait elemezt\u00fck retrospekt\u00edv m\u00f3don. 44 beteg ker\u00fclt TEM-elj\u00e1r\u00e1ssal ell\u00e1t\u00e1sra rectumneoplasia miatt. Sz\u00f6vettani vizsg\u00e1lattal az elv\u00e1ltoz\u00e1sok k\u00f6z\u00f6tt 12 low grade adenoma, 14 high grade adenoma, 17 invasiv adenocarcinoma \u00e9s 1 neuroendokrin tumor volt. A low grade \u00e9s high grade adenom\u00e1k, illetve adenocarcinom\u00e1k m\u00e9rete k\u00f6z\u00f6tt nem tudtunk szignifik\u00e1ns k\u00fcl\u00f6nbs\u00e9get kimutatni (<jats:italic>p<\/jats:italic>= 0,210). A 30 mm alatti \u00e9s feletti elv\u00e1ltoz\u00e1sok k\u00f6z\u00f6tt a sz\u00f6vettani diagn\u00f3zisok tekintet\u00e9ben szignifik\u00e1ns k\u00fcl\u00f6nbs\u00e9get nem tapasztaltunk (<jats:italic>p<\/jats:italic>= 0,424). A 44 esetb\u0151l 13 esetben a praeoperativ sz\u00f6vettani vizsg\u00e1lat kedvez\u0151bb progn\u00f3zis\u00fa elv\u00e1ltoz\u00e1st jelzett, mint a TEM-excisi\u00f3s prepar\u00e1tumon v\u00e9gzett v\u00e9gleges sz\u00f6vettani elemz\u00e9s (<jats:italic>p<\/jats:italic>&lt; 0,001). A sz\u00f6vettani vizsg\u00e1lat 41 esetben (95,3%) igazolta az \u00e9pben t\u00f6rt\u00e9n\u0151 kimetsz\u00e9st. Mindazon\u00e1ltal a t\u00f6bb darabban vagy mucosectomi\u00e1val t\u00f6rt\u00e9n\u0151 polypectomia \u2013 k\u00fcl\u00f6n\u00f6sen nagym\u00e9ret\u0171 adenom\u00e1k eset\u00e9ben \u2013 nem tekinthet\u0151 elegend\u0151 kezel\u00e9snek, ez\u00e9rt \u2013 m\u00e1s kutat\u00f3csoportokhoz hasonl\u00f3an \u2013 javasoljuk a TEM-technik\u00e1val a teljes rectumfalra kiterjed\u0151 excisi\u00f3t. A pT2 st\u00e1dium\u00fa daganatok eset\u00e9ben a v\u00e1lasztand\u00f3 elj\u00e1r\u00e1s tekintet\u00e9ben a jelenleg is zajl\u00f3 prospekt\u00edv klinikai vizsg\u00e1latok fognak bizonyoss\u00e1got adni.<\/jats:p>","DOI":"10.1556\/maseb.67.2014.6.2","type":"journal-article","created":{"date-parts":[[2014,12,13]],"date-time":"2014-12-13T03:32:11Z","timestamp":1418441531000},"page":"329-333","source":"Crossref","is-referenced-by-count":1,"title":["Is radicality granted? 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