{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:45:28Z","timestamp":1790707528781,"version":"4.1.0"},"reference-count":41,"publisher":"Akademiai Kiado Zrt.","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,3,1]]},"abstract":"<jats:p>A szerz\u0151k a hydrops foetus el\u0151fordul\u00e1si gyakoris\u00e1g\u00e1t, l\u00e9trej\u00f6tt\u00e9nek okait vizsg\u00e1lt\u00e1k. \u00d6t \u00e9v alatt 555 foetalis \u00e9s neonat\u00e1lis autopszi\u00e1s vizsg\u00e1latot v\u00e9geztek. Hydropsot igazoltak 28 magzatn\u00e1l. H\u00e1rom esetben Rh-izoimmuniz\u00e1ci\u00f3 \u00e1llt a h\u00e1tt\u00e9rben, 25 foetusn\u00e1l nem immun hydrops ker\u00fclt meg\u00e1llap\u00edt\u00e1sra. Huszon\u00f6t esetben siker\u00fclt a hydrops kiv\u00e1lt\u00f3 ok\u00e1t tiszt\u00e1zni, az ok 3 esetben felder\u00edtetlen maradt. Tizenk\u00e9t esetben k\u00f6z\u00e9pid\u0151s spont\u00e1n vet\u00e9l\u00e9s, illetve in utero elhal\u00e1s t\u00f6rt\u00e9nt, m\u00edg 12 foetusn\u00e1l orvosi indok alapj\u00e1n t\u00f6rt\u00e9nt a terhess\u00e9g termin\u00e1l\u00e1sa. Emellett 4 \u00fajsz\u00fcl\u00f6ttkorban meghalt beteget is vizsg\u00e1ltak. Az orvosi indok alapj\u00e1n t\u00f6rt\u00e9n\u0151 terhess\u00e9gmegszak\u00edt\u00e1sn\u00e1l a foetusok \u00e1tlagos kora a 16. \u00e9s a 20. geszt\u00e1ci\u00f3s h\u00e9t k\u00f6z\u00f6tt volt, m\u00edg a k\u00f6z\u00e9pid\u0151s spont\u00e1n vet\u00e9l\u00e9s \u00e9s in utero elhal\u00e1s eset\u00e9n ez a 24. terhess\u00e9gi hetet jelentette. A patol\u00f3giai vizsg\u00e1lat valamennyi esetben a terhess\u00e9gi korhoz k\u00e9pest v\u00e1rhat\u00f3 tests\u00falyn\u00f6veked\u00e9s\u00e9t, periferi\u00e1s oedem\u00e1t, ascitest, illetve hydrothoraxot igazolt. Az esetek fel\u00e9ben hydropericardium is l\u00e1that\u00f3 volt. Hepatosplenomeg\u00e1lia, cardiomeg\u00e1lia, pulmon\u00e1lis hypoplasia, fokozott extramedull\u00e1ris hemopoezis, placenta oedema valamennyi esetben megfigyelhet\u0151 volt. A nem immun hydrops h\u00e1tter\u00e9ben a k\u00f6vetkez\u0151 rendelleness\u00e9geket tal\u00e1lt\u00e1k: 4 esetben cardi\u00e1lis malformati\u00f3t, 1 esetben szkelet\u00e1lis rendelleness\u00e9get, 3 foetusn\u00e1l kromosz\u00f3marendelleness\u00e9get, 2 foetusn\u00e1l cysticus hygrom\u00e1t, 3 esetben iker-iker transzf\u00fazi\u00f3val j\u00e1r\u00f3 monochorialis diamnialis ikerterhess\u00e9get, 7 esetben infekci\u00f3t, 1 foetusn\u00e1l sacrococcyge\u00e1lis teratom\u00e1t. K\u00e9t esetben a kiv\u00e1lt\u00f3 ok anyai betegs\u00e9get jelentett. A klinikai \u00e9s patol\u00f3giai diagn\u00f3zisokat \u00f6sszehasonl\u00edtva meg\u00e1llap\u00edtott\u00e1k, hogy a nem immun hydrops k\u00f3rok\u00e1val kapcsolatban csup\u00e1n 3 esetben volt teljes egyez\u00e9s a klinikai v\u00e9lem\u00e9nnyel. A patol\u00f3giai vizsg\u00e1lat \u00e1ltal felt\u00e1rt k\u00f3rokot az \u00f6r\u00f6kl\u0151d\u00e9s, ter\u00e1pi\u00e1s lehet\u0151s\u00e9gek m\u00e9rlegel\u00e9se szempontj\u00e1b\u00f3l 10 esetben szignifik\u00e1nsnak v\u00e9lem\u00e9nyezt\u00e9k. A szerz\u0151k kiemelik nem immun hydrops eset\u00e9n a r\u00e9szletes patol\u00f3giai vizsg\u00e1lat sz\u00fcks\u00e9gess\u00e9g\u00e9t, a klinikai vizsg\u00e1latokkal val\u00f3 korrel\u00e1ci\u00f3 meghat\u00e1roz\u00e1s\u00e1nak fontoss\u00e1g\u00e1t, a szerol\u00f3giai vizsg\u00e1latok jelent\u0151s\u00e9g\u00e9t \u00e9s a t\u00e1rsszakm\u00e1kkal val\u00f3 egy\u00fcttm\u0171k\u00f6d\u00e9s sz\u00fcks\u00e9gess\u00e9get a hydropsos magzatokkal kapcsolatos tov\u00e1bbi teend\u0151k meghat\u00e1roz\u00e1sa \u00e9rdek\u00e9ben.<\/jats:p>","DOI":"10.1556\/oh.2007.27951","type":"journal-article","created":{"date-parts":[[2007,3,26]],"date-time":"2007-03-26T19:17:41Z","timestamp":1174936661000},"page":"457-463","source":"Crossref","is-referenced-by-count":4,"title":["Hydrops foetus universalis \u2013 a retrospective study"],"prefix":"10.1556","volume":"148","author":[{"given":"L\u00e1szl\u00f3","family":"Kaiser","sequence":"first","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Patol\u00f3giai Int\u00e9zet Szeged \u00c1llom\u00e1s u. 2. 6724"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antal","family":"Arany","sequence":"additional","affiliation":[{"name":"2 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Sz\u00fcl\u00e9szeti- \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9la","family":"Veszpr\u00e9mi","sequence":"additional","affiliation":[{"name":"2 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Sz\u00fcl\u00e9szeti- \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikl\u00f3s","family":"Vizer","sequence":"additional","affiliation":[{"name":"2 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Sz\u00fcl\u00e9szeti- \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0095-5108(05)70061-0","volume":"27","year":"2000","journal-title":"Clin Perinatol."},{"key":"atypb2","first-page":"187","volume":"28","year":"2001","journal-title":"Clin Exp Obstet Gynecol."},{"key":"atypb3","first-page":"15","volume":"1","year":"2000","journal-title":"Acta Obstet Gynecol Scand."},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/jmf.10.3.175.181-9","volume":"10","year":"2001","journal-title":"J Matern Fetal Med."},{"key":"atypb5","first-page":"2","volume":"202","year":"1998","journal-title":"Z Geburtshilfe Neonatol."},{"key":"atypb6","first-page":"2529","volume":"46","year":"1990","journal-title":"Orv. 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