{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T16:04:13Z","timestamp":1648742653694},"reference-count":30,"publisher":"Akademiai Kiado Zrt.","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4,1]]},"abstract":"<jats:p>Az intravascularis lymphomatosis ritka, high-grade malignit\u00e1s\u00fa non-Hodgkin lymphoma, melyben a sejtek immunhisztok\u00e9miailag B- vagy T-sejteknek bizonyulnak. A legink\u00e1bb \u00e9rintett szervek a b\u0151r \u00e9s a k\u00f6zponti idegrendszer. A leggyakoribb t\u00fcnetek k\u00f6z\u00e9 sorolhat\u00f3 az intermitt\u00e1l\u00f3 l\u00e1z, fok\u00e1lis neurol\u00f3giai t\u00fcnetek, progressz\u00edv demencia. A laborparam\u00e9terek emelkedett s\u00fcllyed\u00e9st, an\u00e9mi\u00e1t, magas LDH-szintet mutatnak, a cerebr\u00e1lis k\u00e9palkot\u00f3 elj\u00e1r\u00e1sok \u00e1ltal\u00e1ban aspecifikusnak bizonyulnak. A v\u00e9gleges diagn\u00f3zis csak biopszia seg\u00edts\u00e9g\u00e9vel \u00e1ll\u00edthat\u00f3 fel. Egy, a fenti klinikai t\u00fcneteket mutat\u00f3 beteg eset\u00e9t ismertetik a szerz\u0151k. Az el\u0151z\u0151ekben felsorolt jellegzetes laborleletek mellett a koponya MR vizsg\u00e1lat aspecifikus volt. Paraneoplasi\u00e1s encephalitis gyan\u00faja miatt v\u00e9gzett tumorkutat\u00e1s der\u00edtett f\u00e9nyt mell\u00e9kvese-malignit\u00e1sra, melynek biopszi\u00e1s sz\u00f6vettani vizsg\u00e1lata vezetett a pontos diagn\u00f3zishoz. Az eset kapcs\u00e1n a szerz\u0151k felh\u00edvj\u00e1k a figyelmet a betegs\u00e9g c\u00e9lzott keres\u00e9s\u00e9nek sz\u00fcks\u00e9gess\u00e9g\u00e9re, az \u00e9rintett szervek biopszi\u00e1j\u00e1nak elengedhetetlen volt\u00e1ra gyorsan progredi\u00e1l\u00f3 tiszt\u00e1zatlan tudatzavar, demenci\u00e1nak, stroke-nak vagy encephalitisnek impon\u00e1l\u00f3 klinikai k\u00e9p eset\u00e9n.<\/jats:p>","DOI":"10.1556\/oh.2007.27974","type":"journal-article","created":{"date-parts":[[2007,4,17]],"date-time":"2007-04-17T18:32:49Z","timestamp":1176834769000},"page":"749-752","source":"Crossref","is-referenced-by-count":0,"title":["Intravascular lymphomatosis: diagnostic problems of a rare disease"],"prefix":"10.1556","volume":"148","author":[{"given":"M\u00f3nika","family":"Sz\u0151ts","sequence":"first","affiliation":[{"name":"1 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Neurol\u00f3giai Klinika P\u00e9cs R\u00e9t u. 2. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Bors","sequence":"additional","affiliation":[{"name":"1 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Neurol\u00f3giai Klinika P\u00e9cs R\u00e9t u. 2. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Endre","family":"K\u00e1lm\u00e1n","sequence":"additional","affiliation":[{"name":"2 Patol\u00f3giai Int\u00e9zet P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Szap\u00e1ry","sequence":"additional","affiliation":[{"name":"1 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Neurol\u00f3giai Klinika P\u00e9cs R\u00e9t u. 2. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"Ill\u00e9s","sequence":"additional","affiliation":[{"name":"1 P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Neurol\u00f3giai Klinika P\u00e9cs R\u00e9t u. 2. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3171\/jns.1999.90.2.0355","volume":"90","year":"1999","journal-title":"J. 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