{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:14:48Z","timestamp":1785208488379,"version":"3.55.0"},"reference-count":21,"publisher":"Akademiai Kiado Zrt.","issue":"Supplement-1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4,1]]},"abstract":"<jats:p>A sziszt\u00e9m\u00e1s autoimmun betegs\u00e9gek a klinikai immunol\u00f3gia \u00e9s reumatol\u00f3gia t\u00e1rgyk\u00f6r\u00e9be tartoz\u00f3, j\u00f3l meghat\u00e1rozott, elk\u00fcl\u00f6n\u00edthet\u0151 betegs\u00e9gcsoportot alkotnak, amelyek hasonl\u00f3s\u00e1guk ellen\u00e9re sz\u00e1mos \u00f6n\u00e1ll\u00f3 saj\u00e1toss\u00e1ggal jellemezhet\u0151k. Ez a hasonl\u00f3s\u00e1g \u00e9s k\u00fcl\u00f6nb\u00f6z\u0151s\u00e9g megnyilv\u00e1nul mind a k\u00f3roki t\u00e9nyez\u0151kben (a genetikai \u00e9s k\u00f6rnyezeti faktorok ar\u00e1ny\u00e1ban), mind a patomechanizmusban (a sejtes vagy humor\u00e1lis immunv\u00e1lasz dominanci\u00e1j\u00e1ban), a k\u00f3rlefoly\u00e1sban (hull\u00e1mz\u00f3 vagy kr\u00f3nikusan progressz\u00edv jellegben) \u00e9s a klinikai t\u00fcnetek soksz\u00edn\u0171s\u00e9g\u00e9ben (sz\u00e1mos c\u00e9lszerv vagy egy-egy domin\u00e1ns c\u00e9lszerv\/sz\u00f6vet \u00e9rintetts\u00e9g\u00e9ben). A szerz\u0151k jelen munk\u00e1ban n\u00e9gy jellegzetes sziszt\u00e9m\u00e1s autoimmun betegs\u00e9g, a sziszt\u00e9m\u00e1s lupus erythematosus, a Sj\u00f6gren-k\u00f3r, a dermato-polymyositis \u00e9s a sziszt\u00e9m\u00e1s sclerosis saj\u00e1toss\u00e1gainak le\u00edr\u00e1sa r\u00e9v\u00e9n ismertetik ezen k\u00f3rk\u00e9pek \u00e9s \u00e1ltal\u00e1ban a sziszt\u00e9m\u00e1s autoimmun betegs\u00e9gek k\u00f6z\u00f6s jellemvon\u00e1sait \u00e9s egyidej\u0171leg azt a soksz\u00edn\u0171s\u00e9get, egyedi jellegzetess\u00e9get, amely m\u00e9g egy-egy k\u00f3rk\u00e9pen bel\u00fcl is megfigyelhet\u0151.<\/jats:p>","DOI":"10.1556\/oh.2007.28035","type":"journal-article","created":{"date-parts":[[2007,4,4]],"date-time":"2007-04-04T17:16:33Z","timestamp":1175706993000},"page":"44-51","source":"Crossref","is-referenced-by-count":1,"title":["Shared and distinctive characteristics of systemic autoimmune disorders"],"prefix":"10.1556","volume":"148","author":[{"given":"Emese","family":"Kiss","sequence":"first","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Belgy\u00f3gy\u00e1szati Int\u00e9zet, III. sz. 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