{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T04:22:08Z","timestamp":1648614128452},"reference-count":8,"publisher":"Akademiai Kiado Zrt.","issue":"27","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:p>A szerz\u0151k s\u00falyos dyspno\u00e9s, extr\u00e9m pulmonalis hipert\u00f3ni\u00e1ban \u00e9s nagyfok\u00fa cor pulmonale chronicumban szenved\u0151, 57 \u00e9ves n\u0151beteg esetismertet\u00e9s\u00e9ben a pulmonalis hipert\u00f3nia ritka ok\u00e1t mutatj\u00e1k be. A boncol\u00e1s sor\u00e1n bronchioloalveolaris mint\u00e1zat\u00fa adenocarcinoma igazol\u00f3dott, amely valamennyi t\u00fcd\u0151lebenyt \u00e9rintette. A t\u00fcd\u0151kapui nyirokcsom\u00f3kban \u00e1tt\u00e9t helyezkedett el. Sz\u00f6vettanilag az arteria pulmonalis kis \u00e1gaiban tumorsejtemb\u00f3lusok, intim\u00e1lis fibrosis, fibrinkiv\u00e1l\u00e1s, valamint a nyirokerekben lymphangiosis carcinomatosa volt megfigyelhet\u0151. Az adenocarcinoma intrapulmonalis terjed\u00e9s\u00e9t val\u00f3sz\u00edn\u0171leg a hilusi nyirokcsom\u00f3 \u00e1tt\u00e9tb\u0151l a ductus thoracicuson kereszt\u00fcl l\u00e9trej\u00f6tt izol\u00e1lt hematog\u00e9n sz\u00f3r\u00e1s okozta. A szerz\u0151k elemzik a tumoros betegs\u00e9gekhez t\u00e1rsul\u00f3 pulmonalis hipert\u00f3nia kialakul\u00e1s\u00e1nak lehets\u00e9ges mechanizmusait, valamint bemutatj\u00e1k az arteria pulmonalisban daganatsejtek hat\u00e1s\u00e1ra kialakul\u00f3 thromboticus microangiopathia k\u00f3rsz\u00f6vettani jellegzetess\u00e9geit. R\u00e1mutatnak az ut\u00f3bbi differenci\u00e1ldiagnosztikai jelent\u0151s\u00e9g\u00e9re.<\/jats:p>","DOI":"10.1556\/oh.2007.28067","type":"journal-article","created":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T13:53:30Z","timestamp":1183384410000},"page":"1281-1285","source":"Crossref","is-referenced-by-count":0,"title":["Primary adenocarcinoma of the lung causing pulmonary tumor thrombotic microangiopathy"],"prefix":"10.1556","volume":"148","author":[{"given":"Andr\u00e1s","family":"V\u00f6r\u00f6s","sequence":"first","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem Szent-Gy\u00f6rgyi Albert Orvos- \u00e9s Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Centrum, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Patol\u00f3gia Int\u00e9zet Szeged \u00c1llom\u00e1s u. 2. 6720"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Kaiser","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem Szent-Gy\u00f6rgyi Albert Orvos- \u00e9s Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Centrum, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Patol\u00f3gia Int\u00e9zet Szeged \u00c1llom\u00e1s u. 2. 6720"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"Somfay","sequence":"additional","affiliation":[{"name":"2 Szegedi Tudom\u00e1nyegyetem Szent-Gy\u00f6rgyi Albert Orvos- \u00e9s Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Centrum, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar T\u00fcd\u0151gy\u00f3gy\u00e1szati Tansz\u00e9k Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"P\u00e1link\u00e1s","sequence":"additional","affiliation":[{"name":"3 Erzs\u00e9bet K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet Belgy\u00f3gy\u00e1szati Oszt\u00e1ly H\u00f3dmez\u0151v\u00e1s\u00e1rhely"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","first-page":"90","volume":"12","year":"2006","journal-title":"Med. 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