{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T21:10:08Z","timestamp":1708031408501},"reference-count":17,"publisher":"Akademiai Kiado Zrt.","issue":"28","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic>A heveny k\u00f6t\u0151h\u00e1rtya-gyullad\u00e1s (conjunctivitis) fert\u0151z\u00e9ses \u00e9s nem fert\u0151z\u00e9ses eredet\u0171 lehet. A fert\u0151z\u00e9ses eredet\u0171 j\u00e1rv\u00e1nyos conjunctivitisek (conjunctivitis epidemica) k\u00f3rokoz\u00f3i v\u00edrusok, ezen bel\u00fcl els\u0151sorban az adenov\u00edrusok k\u00fcl\u00f6nb\u00f6z\u0151 t\u00edpusai.<jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>A szerz\u0151k c\u00e9lja egy keratoconjunctivitis j\u00e1rv\u00e1ny epidemiol\u00f3giai le\u00edr\u00e1sa volt a vir\u00e1lis k\u00f3rokoz\u00f3 molekul\u00e1ris kimutat\u00e1s\u00e1val.<jats:italic>M\u00f3dszer:<\/jats:italic>A j\u00e1rv\u00e1ny \u2013 r\u00e9szben retrospekt\u00edv \u2013 felder\u00edt\u00e9s\u00e9ben klasszikus j\u00e1rv\u00e1ny\u00fcgyi m\u00f3dszereket alkalmaztak. A laborat\u00f3riumi etiol\u00f3giai vizsg\u00e1lat az adenov\u00edrus hexon r\u00e9gi\u00f3j\u00e1nak kimutat\u00e1s\u00e1val polimer\u00e1z l\u00e1ncreakci\u00f3val (PCR), majd szekven\u00e1l\u00e1ssal t\u00f6rt\u00e9nt frissen gy\u0171jt\u00f6tt conjunctiva-v\u00e1lad\u00e9kb\u00f3l.<jats:italic>Eredm\u00e9nyek:<\/jats:italic>A keratoconjunctivitis j\u00e1rv\u00e1nyban \u00f6sszesen 60-an betegedtek meg 2006. okt\u00f3ber 9. \u00e9s december 18-a k\u00f6z\u00f6tt h\u00e9t baranyai telep\u00fcl\u00e9sen. A betegek \u00e1tlag\u00e9letkora 51,2 \u00e9v volt. A vezet\u0151 t\u00fcnetek a conjunctiva bel\u00f6vellts\u00e9ge (100%), a k\u00f6nnyez\u00e9s (94%), az idegentest-\u00e9rz\u00e9s (83%) \u00e9s a hom\u00e1lyos l\u00e1t\u00e1s (76%) voltak. Az esetek fel\u00e9ben mindk\u00e9t szem \u00e9rintett volt. A fert\u0151z\u00e9s k\u00f6zvetlen kontaktussal terjedt r\u00e9szben nosocomi\u00e1lisan, a szem\u00e9szeti szakell\u00e1t\u00e1s sor\u00e1n. Nyolc conjunctivav\u00e1lad\u00e9kb\u00f3l 5-ben (62,5%) genetikailag azonos, 8-as t\u00edpus\u00fa adenov\u00edrust lehetett kimutatni (HAdV8\/Baranya\/2006\/HUN; EF210714), mely 100%-ban azonos volt egy Ausztri\u00e1ban 2004-ben kimutatott adenov\u00edrussal (DQ149614).<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>A r\u00e9szben a szem\u00e9szeti ell\u00e1t\u00e1shoz kapcsol\u00f3d\u00f3 nosocomi\u00e1lis keratoconjunctivitis-j\u00e1rv\u00e1nyt az adenov\u00edrus 8-as t\u00edpusa okozta. A megbeteged\u00e9s klinikai felismer\u00e9se, laborat\u00f3riumi diagnosztik\u00e1ja \u00e9s a j\u00e1rv\u00e1ny\u00fcgyi int\u00e9zked\u00e9sek egy\u00fcttesen sz\u00fcks\u00e9gesek a keratoconjunctivitis-fert\u0151z\u00e9sek \u00e9s a k\u00f6vetkezm\u00e9nyes j\u00e1rv\u00e1ny megel\u0151z\u00e9s\u00e9hez.<\/jats:p>","DOI":"10.1556\/oh.2007.28076","type":"journal-article","created":{"date-parts":[[2007,7,6]],"date-time":"2007-07-06T13:46:53Z","timestamp":1183729613000},"page":"1311-1315","source":"Crossref","is-referenced-by-count":0,"title":["Molecular detection of adenovirus type 8 epidemic keratoconjunctivitis in Hungary"],"prefix":"10.1556","volume":"148","author":[{"given":"G\u00e1bor","family":"Reuter","sequence":"first","affiliation":[{"name":"1 \u00c1llami N\u00e9peg\u00e9szs\u00e9g\u00fcgyi \u00e9s Tisztiorvosi Szolg\u00e1lat Baranya Megyei Int\u00e9zete Region\u00e1lis Virol\u00f3giai Laborat\u00f3rium P\u00e9cs Szabads\u00e1g u. 7. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edina","family":"Meleg","sequence":"additional","affiliation":[{"name":"1 \u00c1llami N\u00e9peg\u00e9szs\u00e9g\u00fcgyi \u00e9s Tisztiorvosi Szolg\u00e1lat Baranya Megyei Int\u00e9zete Region\u00e1lis Virol\u00f3giai Laborat\u00f3rium P\u00e9cs Szabads\u00e1g u. 7. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Kiss","sequence":"additional","affiliation":[{"name":"2 \u00c1NTSZ J\u00e1rv\u00e1ny\u00fcgyi Oszt\u00e1ly P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00f3ra","family":"Albert","sequence":"additional","affiliation":[{"name":"3 \u00c1NTSZ Koml\u00f3i, P\u00e9csv\u00e1radi, S\u00e1sdi V\u00e1rosi Int\u00e9zete Koml\u00f3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Fekete","sequence":"additional","affiliation":[{"name":"2 \u00c1NTSZ J\u00e1rv\u00e1ny\u00fcgyi Oszt\u00e1ly P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Sz\u0171cs","sequence":"additional","affiliation":[{"name":"1 \u00c1llami N\u00e9peg\u00e9szs\u00e9g\u00fcgyi \u00e9s Tisztiorvosi Szolg\u00e1lat Baranya Megyei Int\u00e9zete Region\u00e1lis Virol\u00f3giai Laborat\u00f3rium P\u00e9cs Szabads\u00e1g u. 7. 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","volume-title":"Clinical Virology","year":"2002"},{"key":"atypb2","volume-title":"Principles and practice of clinical virology","year":"2004"},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1093\/infdis\/167.6.1307","volume":"167","year":"1993","journal-title":"J. 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