{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T17:41:53Z","timestamp":1708018913722},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"27","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:p>Az ut\u00f3bbi 10 \u00e9vben ugr\u00e1sszer\u0171en megn\u0151tt az \u00e9rdekl\u0151d\u00e9s a kil\u00e9gzett leveg\u0151 \u00e9s ezen kereszt\u00fcl a l\u00e9g\u00fati gyullad\u00e1s vizsg\u00e1lata ir\u00e1nt a k\u00fcl\u00f6nb\u00f6z\u0151 t\u00fcd\u0151betegs\u00e9gekben. A gyullad\u00e1s monitoroz\u00e1sa seg\u00edthet e k\u00f3rk\u00e9pek differenci\u00e1ldiagn\u00f3zis\u00e1ban, s\u00falyoss\u00e1guk meg\u00edt\u00e9l\u00e9s\u00e9ben \u00e9s a megfelel\u0151 ter\u00e1pia be\u00e1ll\u00edt\u00e1s\u00e1ban. Az \u00faj, noninvaz\u00edv vizsg\u00e1l\u00f3m\u00f3dszerek k\u00f6z\u00fcl legismertebb a kil\u00e9gzett leveg\u0151 nitrog\u00e9n-monoxid-koncentr\u00e1ci\u00f3j\u00e1nak m\u00e9r\u00e9se, amely napjainkban nemzetk\u00f6zileg elfogadott aj\u00e1nl\u00e1sok alapj\u00e1n a kereskedelmi forgalomban is kaphat\u00f3 m\u00e9r\u0151m\u0171szerek seg\u00edts\u00e9g\u00e9vel t\u00f6rt\u00e9nik. Az asztm\u00e1s betegekben a kil\u00e9gzett nitrog\u00e9n-monoxid-koncentr\u00e1ci\u00f3 jelent\u0151sen emelkedett, \u00e9s szoros \u00f6sszef\u00fcgg\u00e9st mutat a l\u00e9gutak eozinofilsejtes gyullad\u00e1s\u00e1val, a l\u00e9g\u00fati hiperreaktivit\u00e1s m\u00e9rt\u00e9k\u00e9vel \u00e9s a beteg panaszaival. E betegekben a kil\u00e9gzett nitrog\u00e9n-monoxid m\u00e9r\u00e9s\u00e9n alapul\u00f3 gy\u00f3gyszeres be\u00e1ll\u00edt\u00e1s a klasszikus kezel\u00e9si strat\u00e9gi\u00e1khoz k\u00e9pest jobb asztmakontrollt eredm\u00e9nyezhet. M\u00e1s t\u00fcd\u0151betegs\u00e9gekben, \u00edgy p\u00e9ld\u00e1ul a kr\u00f3nikus obstrukt\u00edv pulmonalis megbeteged\u00e9sben a kil\u00e9gzett nitrog\u00e9n-monoxid m\u00e9r\u00e9se a szteroidra val\u00f3 v\u00e1laszk\u00e9szs\u00e9g megj\u00f3sol\u00e1s\u00e1ban seg\u00edtheti a klinikust, m\u00edg t\u00fcd\u0151transzplant\u00e1lt betegekben rejtett infekci\u00f3k vagy kil\u00f6k\u0151d\u00e9si reakci\u00f3k indik\u00e1tora lehet.<\/jats:p>","DOI":"10.1556\/oh.2007.28081","type":"journal-article","created":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T13:53:30Z","timestamp":1183384410000},"page":"1251-1257","source":"Crossref","is-referenced-by-count":1,"title":["Exhaled nitric oxide in diagnostics and monitoring of lung diseases"],"prefix":"10.1556","volume":"148","author":[{"given":"Bal\u00e1zs","family":"Antus","sequence":"first","affiliation":[{"name":"1 Orsz\u00e1gos Kor\u00e1nyi TBC \u00e9s Pulmonol\u00f3giai Int\u00e9zet III. 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