{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T17:57:37Z","timestamp":1648922257629},"reference-count":19,"publisher":"Akademiai Kiado Zrt.","issue":"37","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,9,1]]},"abstract":"<jats:p>A ver\u0151ereket sziszt\u00e9m\u00e1san \u00e9rint\u0151 atheroscleroticus folyamat jellemz\u0151i az id\u0151ben elh\u00faz\u00f3d\u00f3 progresszivit\u00e1s mellett a hirtelen kialakul\u00f3, tromb\u00f3zissal, emboliz\u00e1ci\u00f3val kapcsolatos \u00e9relz\u00e1r\u00f3d\u00e1sok is. A k\u00fcl\u00f6nb\u00f6z\u0151 lokaliz\u00e1ci\u00f3j\u00fa perif\u00e9ri\u00e1s art\u00e9ri\u00e1s \u00e9rbetegs\u00e9g fulmin\u00e1ns form\u00e1ja igen s\u00falyos klinikai t\u00fcnetek k\u00eds\u00e9ret\u00e9ben manifeszt\u00e1l\u00f3dik. A gyors diagnosztik\u00e1t k\u00f6vet\u0151en az \u00e9rseb\u00e9sz, a radiol\u00f3gus \u00e9s az angiol\u00f3gus belgy\u00f3gy\u00e1sz konzult\u00e1ci\u00f3ja ut\u00e1ni ter\u00e1pi\u00e1ban manaps\u00e1g egyre mark\u00e1nsabb hely illeti meg a lok\u00e1lis thrombolysist. A m\u00f3dszer l\u00e9nyege a thrombusba helyezett kat\u00e9teren kereszt\u00fcl inf\u00fazi\u00f3ban elny\u00fajtottan adott sz\u00f6veti plazminog\u00e9n aktiv\u00e1tor thrombolyticus hat\u00e1s\u00e1nak kihaszn\u00e1l\u00e1sa. A revascularisati\u00f3s eredm\u00e9ny angiogr\u00e1fi\u00e1val ellen\u0151rizhet\u0151. A szerz\u0151k bemutatj\u00e1k a lok\u00e1lis thrombolyticus kezel\u00e9s indik\u00e1ci\u00f3it \u00e9s kontraindik\u00e1ci\u00f3it perif\u00e9ri\u00e1s art\u00e9ri\u00e1s \u00e9rbetegs\u00e9gben, majd k\u00e9t saj\u00e1t eset\u00fck r\u00f6vid prezent\u00e1l\u00e1s\u00e1val is al\u00e1t\u00e1masztj\u00e1k a k\u00e9rd\u00e9s aktu\u00e1lis fontoss\u00e1g\u00e1t. Diszkut\u00e1lj\u00e1k a nemzetk\u00f6zi szakirodalom adatait, melyek \u00e1ltal\u00e1nos meg\u00e1llap\u00edt\u00e1sak\u00e9nt az hangs\u00falyozand\u00f3, hogy a lok\u00e1lisan alkalmazott thrombolysis egyen\u00e9rt\u00e9k\u0171 az \u00e9rseb\u00e9szeti beavatkoz\u00e1ssal. Bizonyos helyzetekben, igen komplex okokkal kapcsolatban az els\u0151k\u00e9nt v\u00e1lasztand\u00f3 kezel\u00e9si elj\u00e1r\u00e1sk\u00e9nt aj\u00e1nlhat\u00f3. A t\u00e9ma feldolgoz\u00e1sakor levonhat\u00f3 legfontosabb tanuls\u00e1gok, a j\u00f6v\u0151beli fejl\u0151d\u00e9s v\u00e1rhat\u00f3 \u00fatjainak bemutat\u00e1s\u00e1val z\u00e1rul a refer\u00e1tum.<\/jats:p>","DOI":"10.1556\/oh.2007.28196","type":"journal-article","created":{"date-parts":[[2007,9,7]],"date-time":"2007-09-07T14:27:46Z","timestamp":1189175266000},"page":"1737-1744","source":"Crossref","is-referenced-by-count":0,"title":["Local thrombolysis in the treatment of peripheral arterial vascular diseases"],"prefix":"10.1556","volume":"148","author":[{"given":"J\u00e1nos","family":"Mikita","sequence":"first","affiliation":[{"name":"1 Debreceni Egyetem, Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum Belgy\u00f3gy\u00e1szati Int\u00e9zet, II. 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