{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T16:40:17Z","timestamp":1708447217134},"reference-count":33,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,1]]},"abstract":"<jats:p>A foetopathologiai vizsg\u00e1lat nagy jelent\u0151s\u00e9g\u0171, hiszen egy k\u00f6vetkez\u0151 terhess\u00e9g v\u00e1llal\u00e1s\u00e1nak szempontjait szem el\u0151tt tartva \u2013 egyebek mellett \u2013 az el\u0151fordul\u00f3 rendelleness\u00e9g ism\u00e9tl\u0151d\u00e9s\u00e9nek es\u00e9lyeit hivatott meg\u00edt\u00e9lni.<jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>Vizsg\u00e1lataink c\u00e9lj\u00e1ul a praenatalis ultrahang-diagnosztika hat\u00e9konys\u00e1g\u00e1nak, illetve a terhess\u00e9gmegszak\u00edt\u00e1st k\u00f6vet\u0151 foetopathologiai vizsg\u00e1lat eredm\u00e9ny\u00e9nek meg\u00edt\u00e9l\u00e9s\u00e9t, elemz\u00e9s\u00e9t t\u0171zt\u00fck ki a jelent\u0151sebb craniospinalis malformati\u00f3k tekintet\u00e9ben.<jats:italic>M\u00f3dszer:<\/jats:italic>Vizsg\u00e1lataink sor\u00e1n az 1995. janu\u00e1r 1. \u00e9s 2006. december 31. k\u00f6z\u00f6tt a Semmelweis Egyetem \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar I. sz\u00e1m\u00fa Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinik\u00e1j\u00e1n craniospinalis malformatio miatt megszak\u00edtott 339 terhess\u00e9g adatait dolgoztuk fel.<jats:italic>Eredm\u00e9nyek:<\/jats:italic>A vizsg\u00e1lt esetekben az anyai \u00e9letkor medi\u00e1n \u00e9rt\u00e9ke 15 \u00e9s 47 \u00e9ves sz\u00e9ls\u0151 \u00e9rt\u00e9kek k\u00f6z\u00f6tt 27 \u00b1 5,8 \u00e9v volt. 83 esetben (24,5%) terhel\u0151 sz\u00fcl\u00e9szeti-n\u0151gy\u00f3gy\u00e1szati vagy genetikai el\u0151zm\u00e9ny fordult el\u0151. A vizsg\u00e1lt 339 esetb\u0151l 231-ben (68,1%) az ultrahangvizsg\u00e1lattal nyert \u00e9s a foetopathologiai vizsg\u00e1lattal igazolt diagn\u00f3zisok teljesen megegyeztek, 82 esetben (24,2%) r\u00e9szleges egyez\u00e9s mellett a boncol\u00e1s tov\u00e1bbi k\u00f3rism\u00e9k fel\u00e1ll\u00edt\u00e1s\u00e1ra adott m\u00f3dot, m\u00edg 26 esetben (7,7%) a praenatalis ultrahangvizsg\u00e1lat, illetve a foetopathologiai vizsg\u00e1lat elt\u00e9r\u0151 eredm\u00e9nyeket igazolt. Ez ut\u00f3bbi 26 eset fel\u00e9ben (13 eset) a vet\u00e9l\u00e9sindukci\u00f3 javallat\u00e1t ultrahangvizsg\u00e1lattal igazolt hydrocephalus k\u00e9pezte, melyet a boncol\u00e1s nem er\u0151s\u00edtett meg, illet\u0151leg egy\u00e9b craniospinalis rendelleness\u00e9g(ek) fenn\u00e1ll\u00e1s\u00e1t igazolta.<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>Mivel a hydrocephalus k\u00f3rism\u00e9z\u00e9se esetenk\u00e9nt \u2013 tekintettel a soksz\u00edn\u0171 k\u00f3reredetre \u2013 a t\u00f6bbi craniospinalis rendelleness\u00e9ghez k\u00e9pest k\u00e9s\u0151bbi geszt\u00e1ci\u00f3s korban lehets\u00e9ges csak, kijelenthet\u0151, hogy \u2013 m\u00e9rlegelve a foetopathologiai vizsg\u00e1latok t\u00fckr\u00e9ben igazol\u00f3dott diagnosztikai hat\u00e9konys\u00e1got \u2013 a hydrocephalus praenatalis ultrahang-diagnosztik\u00e1j\u00e1t a t\u00f6bbi craniospinalis rendelleness\u00e9gt\u0151l k\u00fcl\u00f6n, azok\u00e9t\u00f3l elt\u00e9r\u0151 id\u0151beli \u00e9s ultrahang-metodikai elvek alapj\u00e1n c\u00e9lszer\u0171 \u00e9rtelmezni.<\/jats:p>","DOI":"10.1556\/oh.2008.28136","type":"journal-article","created":{"date-parts":[[2007,12,20]],"date-time":"2007-12-20T14:50:16Z","timestamp":1198162216000},"page":"23-27","source":"Crossref","is-referenced-by-count":1,"title":["Craniospinal malformations in a twelve-year fetopathological study; the efficiency of ultrasonography in view of fetopathological investigations"],"prefix":"10.1556","volume":"149","author":[{"given":"J\u00f3zsef G\u00e1bor","family":"Jo\u00f3","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar I. 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