{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T01:04:52Z","timestamp":1648515892960},"reference-count":16,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,1]]},"abstract":"<jats:p>Az irreverz\u00edbilis sz\u00edv- \u00e9s veseel\u00e9gtelens\u00e9gben szenved\u0151 betegekn\u00e9l ter\u00e1pi\u00e1s lehet\u0151s\u00e9get jelenthet az azonos donorb\u00f3l sz\u00e1rmaz\u00f3, egyidej\u0171, kombin\u00e1lt sz\u00edv- \u00e9s vese\u00e1t\u00fcltet\u00e9s. A m\u00f3dszerben rejl\u0151 sz\u00e1mos el\u0151ny ellen\u00e9re csak kev\u00e9s adat \u00e1ll rendelkez\u00e9sre a hossz\u00fa t\u00e1v\u00fa graftt\u00fal\u00e9l\u00e9st \u00e9s -mortalit\u00e1st illet\u0151en. A szerz\u0151k k\u00f6zlem\u00e9ny\u00fckben besz\u00e1molnak a Magyarorsz\u00e1gon el\u0151sz\u00f6r v\u00e9gzett kombin\u00e1lt sz\u00edv-vese \u00e1t\u00fcltet\u00e9s sor\u00e1n szerzett tapasztalataikr\u00f3l, \u00e9s irodalmi \u00e1ttekint\u00e9sben az elj\u00e1r\u00e1s jogosults\u00e1g\u00e1t elemzik. \u2013 A fiatal, ur\u00e9mi\u00e1s f\u00e9rfi beteg ischaemi\u00e1s eredet\u0171 dilatativ cardiomyopathi\u00e1val sz\u00edvtranszplant\u00e1ci\u00f3s v\u00e1r\u00f3list\u00e1n szerepelt. Tests\u00faly, testm\u00e9ret, AB0-v\u00e9rcsoport alapj\u00e1n egyez\u0151, kad\u00e1ver donorb\u00f3l elt\u00e1vol\u00edtott sz\u00edvvel \u00e9s ves\u00e9vel, negat\u00edv T-sejt-keresztpr\u00f3b\u00e1t k\u00f6vet\u0151en, transzplant\u00e1ci\u00f3t v\u00e9geztek. El\u0151sz\u00f6r a sz\u00edv be\u00fcltet\u00e9se t\u00f6rt\u00e9nt meg, majd a hemodinamikai param\u00e9terek stabiliz\u00e1l\u00f3d\u00e1sa ut\u00e1n azonnal, az egyazon donorb\u00f3l elt\u00e1vol\u00edtott ves\u00e9t transzplant\u00e1lt\u00e1k. Mindk\u00e9t m\u0171t\u00e9t technik\u00e1ja megegyezett azzal, amit az izol\u00e1lt sz\u00edv- vagy vese\u00e1t\u00fcltet\u00e9s sor\u00e1n alkalmaznak. A be\u00fcltetett sz\u00edv \u00e9s vese m\u0171k\u00f6d\u00e9s\u00e9nek param\u00e9terei gyors javul\u00e1st mutattak. A beteg t\u00f6bb mint egy \u00e9vvel a kett\u0151s szerv\u00e1t\u00fcltet\u00e9st k\u00f6vet\u0151en is kompenz\u00e1lt kering\u00e9ssel \u00e9s vesem\u0171k\u00f6d\u00e9ssel, j\u00f3 \u00e1ltal\u00e1nos \u00e1llapotban, akt\u00edv \u00e9letet \u00e9l. A bemutatott eset \u00e9s az irodalmi adatok alapj\u00e1n kijelenthet\u0151, hogy a kombin\u00e1lt sz\u00edv- \u00e9s vese\u00e1t\u00fcltet\u00e9s alternat\u00edv\u00e1t jelent v\u00e9g\u00e1llapot\u00fa sz\u00edv- \u00e9s vesebetegek kezel\u00e9s\u00e9ben. A mindk\u00e9t graftn\u00e1l tapasztalt \u2013 az irodalomb\u00f3l ismert \u2013 alacsonyabb korai rejekci\u00f3s ar\u00e1ny az immunszuppresszi\u00f3s protokolljukat igazolja, illetve felveti a szervek egym\u00e1sra gyakorolt protekt\u00edv hat\u00e1s\u00e1t is.<\/jats:p>","DOI":"10.1556\/oh.2008.28243","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T21:50:23Z","timestamp":1201038623000},"page":"147-152","source":"Crossref","is-referenced-by-count":1,"title":["The first successful combined heart-kidney transplantation in Hungary"],"prefix":"10.1556","volume":"149","author":[{"given":"Tam\u00e1s","family":"Benk\u0151","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika Budapest Baross u. 23. 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imre","family":"Feh\u00e9rv\u00e1ri","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika Budapest Baross u. 23. 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krist\u00f3f","family":"R\u00e1cz","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9r- \u00e9s Sz\u00edvseb\u00e9szeti Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orsolya","family":"Friedrich","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9r- \u00e9s Sz\u00edvseb\u00e9szeti Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ildik\u00f3","family":"G\u00e1lfy","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9r- \u00e9s Sz\u00edvseb\u00e9szeti Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szil\u00e1rd","family":"T\u00f6r\u00f6k","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika Budapest Baross u. 23. 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1d\u00e1m","family":"Remport","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika Budapest Baross u. 23. 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen\u0151","family":"J\u00e1ray","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika Budapest Baross u. 23. 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elek","family":"Bodor","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9r- \u00e9s Sz\u00edvseb\u00e9szeti Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Szabolcs","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00c9r- \u00e9s Sz\u00edvseb\u00e9szeti Klinika Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/ndt\/13.3.723","volume":"13","year":"1998","journal-title":"Nephrol. 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