{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T11:15:30Z","timestamp":1782472530019,"version":"3.54.5"},"reference-count":15,"publisher":"Akademiai Kiado Zrt.","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,3,1]]},"abstract":"<jats:p>Diab\u00e9teszes betegekben a h\u00fagy\u00fati infekci\u00f3k gyakoribbak, illetve s\u00falyosabb k\u00f3rlefoly\u00e1s v\u00e1rhat\u00f3. A k\u00fcl\u00f6nbs\u00e9g n\u0151kben kifejezettebb mind a szimpt\u00f3m\u00e1s infekci\u00f3k, mind az aszimptomatikus bacteriuria vonatkoz\u00e1s\u00e1ban. A k\u00f3rokoz\u00f3 spektrum nem t\u00e9r el l\u00e9nyegesen a nem diab\u00e9teszes betegekben \u00e9szlelt k\u00f3rokoz\u00f3-megoszl\u00e1st\u00f3l. Cystitisek eset\u00e9ben \u2013 vizsg\u00e1latok hi\u00e1ny\u00e1ban \u2013 nem k\u00fcl\u00f6nb\u00f6znek a kezel\u00e9si elvek a nem diab\u00e9teszes betegek kezel\u00e9se sor\u00e1n alkalmazott\u00f3l, de a veseparenchyma gyakori \u00e9rintetts\u00e9ge miatt c\u00e9lszer\u0171nek l\u00e1tszik a biztosan hat\u00e9kony antibiotikum v\u00e1laszt\u00e1sa empirikus ter\u00e1pi\u00e1ra. A pyelonephritis t\u00f6bbnyire kezdeti parenteralis kezel\u00e9st, a sz\u00f6v\u0151dm\u00e9nyek lehet\u0151s\u00e9ge miatt szoros obszerv\u00e1ci\u00f3t, \u00e9s \u00edgy az esetek t\u00f6bbs\u00e9g\u00e9ben hospitaliz\u00e1ci\u00f3t ig\u00e9nyel. Az \n <jats:italic>E. coli<\/jats:italic>\n emelked\u0151 antibiotikum-rezisztenci\u00e1ja miatt a doxycyclin, a sulfamethoxazol empirikus ter\u00e1pi\u00e1ra diab\u00e9teszes betegek h\u00fagy\u00fati infekci\u00f3inak kezel\u00e9s\u00e9re nem javasolt, s\u00falyosabb k\u00f3rform\u00e1kban az amoxycillin\/klavul\u00e1nsav, illetve a fluorokinolonok alkalmaz\u00e1sa is megk\u00e9rd\u0151jelezhet\u0151. Jelenleg m\u00e9g az ambul\u00e1ns gyakorlatban el\u00e9rhet\u0151 antibiotikumok k\u00f6z\u00fcl a 3. gener\u00e1ci\u00f3s cephalosporinok a leghat\u00e9konyabbak. A diab\u00e9teszes betegek sz\u0171r\u00e9se aszimptomatikus bacteriuri\u00e1ra nem javasolt, az alkalmazott antibiotikum-kezel\u00e9s a k\u00e9s\u0151bbi szimpt\u00f3m\u00e1s epiz\u00f3dokat nem v\u00e9di ki.<\/jats:p>","DOI":"10.1556\/oh.2008.28298","type":"journal-article","created":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T14:58:56Z","timestamp":1205938736000},"page":"597-600","source":"Crossref","is-referenced-by-count":6,"title":["Urinary tract infections in diabetes mellitus"],"prefix":"10.1556","volume":"149","author":[{"given":"Endre","family":"Ludwig","sequence":"first","affiliation":[{"name":"1 Egyes\u00edtett Szent Istv\u00e1n \u00e9s Szent L\u00e1szl\u00f3 K\u00f3rh\u00e1z, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Infektol\u00f3giai Tansz\u00e9kcsoport Budapest Nagyv\u00e1rad t\u00e9r 1. 1096"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"atypb1","first-page":"281","volume":"1","year":"1992","journal-title":"Eur. J. Med."},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0163-4453(86)94112-5","volume":"12","year":"1986","journal-title":"J. Infect."},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1001\/archinte.161.11.1421","volume":"161","year":"2001","journal-title":"Arch. Int. Med."},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0891-5520(05)70383-4","volume":"11","year":"1997","journal-title":"Inf. Dis. Clin. North Am."},{"key":"atypb5","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1001\/jama.1977.03280190026020","volume":"238","year":"1977","journal-title":"JAMA"},{"key":"atypb6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1464-5491.1987.tb00825.x","volume":"4","year":"1987","journal-title":"Diabetes Med."},{"key":"atypb7","doi-asserted-by":"crossref","first-page":"392","DOI":"10.2337\/diacare.20.3.392","volume":"20","year":"1997","journal-title":"Diabet. Care"},{"key":"atypb8","first-page":"351","volume":"24","year":"1998","journal-title":"Diabetes Metab."},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.2337\/diacare.25.8.1405","volume":"25","year":"2002","journal-title":"Diabet. Care"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1471-2334-6-54","volume":"6","year":"2006","journal-title":"BMC Infect Dis."},{"key":"atypb11","first-page":"35","volume":"22","year":"2003","journal-title":"Int. J. Antimicrob. Agents"},{"key":"atypb12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.7326\/0003-4819-142-1-200501040-00008","volume":"142","year":"2005","journal-title":"Ann. Intern. Med."},{"key":"atypb13","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/oxfordjournals.aje.a000181","volume":"161","year":"2005","journal-title":"Am. J. Epidemiol."},{"key":"atypb14","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1056\/NEJMoa021042","volume":"347","year":"2002","journal-title":"N. Eng. J. Med."},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1086\/427507","volume":"40","year":"2005","journal-title":"CID"}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/149\/13\/article-p597.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/149\/13\/article-p597.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T10:14:38Z","timestamp":1590574478000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/149\/13\/article-p597.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,1]]},"references-count":15,"journal-issue":{"issue":"13"},"URL":"https:\/\/doi.org\/10.1556\/oh.2008.28298","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,1]]}}}