{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:02:35Z","timestamp":1756382555297},"reference-count":27,"publisher":"Akademiai Kiado Zrt.","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:p>Az autoimmun pancreatitis a kr\u00f3nikus pancreatitis ritka oka. Klinikai jelent\u0151s\u00e9ge m\u00e9gsem lebecs\u00fclend\u0151, mivel r\u00e9szben a rosszindulat\u00fa hasny\u00e1lmirigyr\u00e1kt\u00f3l t\u00f6rt\u00e9n\u0151 elk\u00fcl\u00f6n\u00edt\u00e9se neh\u00e9zs\u00e9get okozhat, r\u00e9szben pedig az id\u00fclt pancreatitisek t\u00f6bbs\u00e9g\u00e9t\u0151l elt\u00e9r\u0151en j\u00f3l kezelhet\u0151, szteroidkezel\u00e9sre teljes regresszi\u00f3ja is el\u0151fordulhat. Klinikai k\u00e9pe nem jellegzetes, az elz\u00e1r\u00f3d\u00e1sos s\u00e1rgas\u00e1g, hasi f\u00e1jdalom, fogy\u00e1s gyakori. A k\u00e9palkot\u00f3 vizsg\u00e1latok jellemz\u0151en a pancreas diff\u00faz megnagyobbod\u00e1s\u00e1t \u00e9s a Wirsung-vezet\u00e9k egyenetlen sz\u0171k\u00fclet\u00e9t mutatj\u00e1k. Autoimmun pancreatitisben szenved\u0151kben az IgG4-immunglobulin n\u00f6vekedett sz\u00e9rumkoncentr\u00e1ci\u00f3j\u00e1t, autoantitesteket \u00e9s IgG4-pozit\u00edv immunsejtek jelenl\u00e9t\u00e9t mutatt\u00e1k ki m\u00e1s sz\u00f6vettani jellegzetess\u00e9gek mellett. A hasny\u00e1lmirigy \u00e9rintetts\u00e9ge mellett egy\u00e9b szervek is megbetegedhetnek, \u00edgy pl. sclerotis\u00e1l\u00f3 cholangitisszel, sialoadenitisszel, retroperitonealis fibrosissal, Riedel-strum\u00e1val \u00e9s gyullad\u00e1sos b\u00e9lbetegs\u00e9gekkel val\u00f3 t\u00e1rsul\u00e1s\u00e1t is le\u00edrt\u00e1k. Mindezek alapj\u00e1n az autoimmun pancreatitis rendszerbetegs\u00e9gnek tarthat\u00f3, sziszt\u00e9m\u00e1s IgG4-asszoci\u00e1lt sclerotis\u00e1l\u00f3 k\u00f3rk\u00e9p egyik megjelen\u00e9si form\u00e1jak\u00e9nt.<\/jats:p>","DOI":"10.1556\/oh.2008.28319","type":"journal-article","created":{"date-parts":[[2008,5,4]],"date-time":"2008-05-04T04:53:41Z","timestamp":1209876821000},"page":"873-876","source":"Crossref","is-referenced-by-count":2,"title":["Autoimmune pancreatitis"],"prefix":"10.1556","volume":"149","author":[{"given":"P\u00e9ter","family":"Igaz","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar II. Belgy\u00f3gy\u00e1szati Klinika Budapest Szentkir\u00e1lyi u. 46. 1088"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"Tulassay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/BF02285209","volume":"40","year":"1995","journal-title":"Dig. Dis. Sci."},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/BF02232341","volume":"6","year":"1961","journal-title":"Am. J. Dig. Dis."},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/MOG.0b013e3282ba5736","volume":"23","year":"2007","journal-title":"Curr. Opin. Gastroenterol."},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00006676-200307000-00001","volume":"27","year":"2003","journal-title":"Pancreas"},{"key":"atypb5","first-page":"28","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb6","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0016-5085(00)70264-2","volume":"118","year":"2000","journal-title":"Gastroenterology"},{"key":"atypb7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00535-007-2044-x","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s00535-007-2047-7","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00535-006-1862-6","volume":"41","year":"2006","journal-title":"J. Gastroenterol."},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00535-007-2045-9","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb11","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1056\/NEJMra061200","volume":"355","year":"2006","journal-title":"N. Eng. J. Med."},{"key":"atypb12","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1002\/bjs.5893","volume":"94","year":"2007","journal-title":"Br. J. Surg."},{"key":"atypb13","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.gtc.2007.03.015","volume":"36","year":"2007","journal-title":"Gastroenterol. Clin. North Am."},{"key":"atypb14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1148\/radiol.2332031436","volume":"233","year":"2004","journal-title":"Radiology"},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1056\/NEJM200103083441005","volume":"344","year":"2001","journal-title":"N. Eng. J. Med."},{"key":"atypb16","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.3748\/wjg.v12.i38.6225","volume":"12","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"atypb17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00535-007-2049-5","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb18","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/01.mpa.0000226881.48204.fd","volume":"33","year":"2006","journal-title":"Pancreas"},{"key":"atypb19","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1067\/mge.2002.122653","volume":"55","year":"2002","journal-title":"Gastrointest. Endosc."},{"key":"atypb20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s00535-007-2050-z","volume":"42","year":"2007","journal-title":"J. Gastroenterol."},{"key":"atypb21","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.cgh.2006.05.017","volume":"4","year":"2006","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"atypb22","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00000478-200301000-00012","volume":"27","year":"2003","journal-title":"Am. J. Surg. Pathol."},{"key":"atypb23","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s00535-002-1108-1","volume":"38","year":"2003","journal-title":"J. Gastroenterol."},{"key":"atypb24","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/01.mpa.0000202950.02988.07","volume":"32","year":"2006","journal-title":"Pancreas"},{"key":"atypb25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1556\/OH.2007.27964","volume":"148","year":"2007","journal-title":"Orv. Hetil."},{"key":"atypb26","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/01.mpa.0000232329.35822.3a","volume":"33","year":"2006","journal-title":"Pancreas"},{"key":"atypb27","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1055\/s-2007-963447","volume":"45","year":"2007","journal-title":"Z. Gastroenterol."}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/149\/19\/article-p873.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/149\/19\/article-p873.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T10:14:22Z","timestamp":1590574462000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/149\/19\/article-p873.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,1]]},"references-count":27,"journal-issue":{"issue":"19"},"URL":"https:\/\/doi.org\/10.1556\/oh.2008.28319","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,1]]}}}