{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:12:56Z","timestamp":1648926776086},"reference-count":22,"publisher":"Akademiai Kiado Zrt.","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:p>Az id\u0151skori maculadegeneratio a fejlett orsz\u00e1gokban m\u00e1ra a vaks\u00e1gi statisztik\u00e1k vezet\u0151j\u00e9v\u00e9 v\u00e1lt. Magyarorsz\u00e1gon is n\u00e9h\u00e1ny sz\u00e1zezerre becs\u00fclhet\u0151 a betegs\u00e9gben szenved\u0151k sz\u00e1ma. A k\u00fcl\u00f6nb\u00f6z\u0151 megjelen\u00e9si form\u00e1k sz\u00e9les sk\u00e1l\u00e1j\u00e1t kor\u00e1bban \u00f6n\u00e1ll\u00f3 betegs\u00e9gnek tekintett\u00e9k. Ami\u00f3ta tiszt\u00e1z\u00f3dott a k\u00f3r teljes vertikuma, patomechanizmusa, valamint fejl\u0151dtek a kezel\u00e9si m\u00f3dszerek, sok esetben j\u00f3 kil\u00e1t\u00e1sok ny\u00edlnak a l\u00e1t\u00e1s meg\u0151rz\u00e9s\u00e9re, esetleg jav\u00edt\u00e1s\u00e1ra is. A szerz\u0151 az elv\u00e1ltoz\u00e1sok le\u00edr\u00e1sa ut\u00e1n r\u00e9szletesen elemzi azokat az elj\u00e1r\u00e1sokat, amelyek m\u00e1r bizony\u00edtottan hat\u00e1sosak, vagy amelyek az elm\u00falt \u00e9vekben ker\u00fcltek az \u00e9rdekl\u0151d\u00e9s homlokter\u00e9be. A betegs\u00e9g megel\u0151z\u00e9s\u00e9n\u00e9l k\u00fcl\u00f6n\u00f6sen a doh\u00e1nyz\u00e1s k\u00e1ros hat\u00e1s\u00e1ra h\u00edvja f\u00f6l a figyelmet. A konzervat\u00edv kezel\u00e9s a kor\u00e1bbi antioxid\u00e1ns-ter\u00e1pia mellett ma m\u00e1r mag\u00e1ban foglalja az \u00fagynevezett metabolikus ter\u00e1pi\u00e1t is. Sz\u00e9les k\u00f6rben haszn\u00e1latosak a k\u00fcl\u00f6nf\u00e9le l\u00e9zerkezel\u00e9sek, kisebb sz\u00e1mban a radioakt\u00edv besug\u00e1rz\u00e1s. Ugyancsak korl\u00e1tozott a hagyom\u00e1nyos seb\u00e9szeti elj\u00e1r\u00e1sok szerepe, de igen \u00edg\u00e9retes a vascularis endothelialis n\u00f6veked\u00e9si faktor elleni szerek haszn\u00e1lata. A szerz\u0151 utal az egyes elj\u00e1r\u00e1sok k\u00f6lts\u00e9geire is.<\/jats:p>","DOI":"10.1556\/oh.2008.28345","type":"journal-article","created":{"date-parts":[[2008,5,16]],"date-time":"2008-05-16T12:34:22Z","timestamp":1210941262000},"page":"989-994","source":"Crossref","is-referenced-by-count":0,"title":["Therapeutic modalities of age-related macular degeneration"],"prefix":"10.1556","volume":"149","author":[{"given":"L\u00e1szl\u00f3","family":"Vezendi","sequence":"first","affiliation":[{"name":"1 Kanizsai Dorottya K\u00f3rh\u00e1z-Rendel\u0151int\u00e9zet Szem\u00e9szeti Oszt\u00e1ly Nagykanizsa Szekeres J. u. 2\u20138. 8800"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/eye.1987.40","volume":"1","year":"1987","journal-title":"Eye"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/0039-6257(80)90021-1","volume":"24","year":"1980","journal-title":"Surv. 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