{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:56:46Z","timestamp":1756461406963},"reference-count":28,"publisher":"Akademiai Kiado Zrt.","issue":"25","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,6,1]]},"abstract":"<jats:p>A sziszt\u00e9m\u00e1s amyloidosis gyakran \u00e9rinti a gastrointestinalis rendszert fek\u00e9ly vagy polypoid elv\u00e1ltoz\u00e1s form\u00e1j\u00e1ban, a vastagbelet k\u00f6rk\u00f6r\u00f6sen sz\u0171k\u00edt\u0151 folyamat azonban k\u00fcl\u00f6n\u00f6sen ritka. Amyloidosis el\u0151fordul\u00e1sa a \u03bb-k\u00f6nny\u0171l\u00e1ncot termel\u0151 myeloma multiplexes betegek kb. 10%-\u00e1ban v\u00e1rhat\u00f3, sz\u00f6vettanilag AL t\u00edpus\u00fa. A hematol\u00f3giai betegs\u00e9g diagn\u00f3zisa azonban szinte minden esetben megel\u0151zi a gastrointestinalis t\u00fcnetek jelentkez\u00e9s\u00e9t.<jats:italic>Esetismertet\u00e9s:<\/jats:italic>Egy 73 \u00e9ves n\u0151beteget an\u00e9mia, hasi f\u00e1jdalom, haematochesia miatt vizsg\u00e1ltunk. A kolonoszk\u00f3pia sor\u00e1n k\u00f6rk\u00f6r\u00f6s sigmab\u00e9lstenosis igazol\u00f3dott, mely neoplasia gyan\u00faj\u00e1t vetette fel. A sz\u0171k\u00fclet megold\u00e1s\u00e1ra sigmaresectio t\u00f6rt\u00e9nt rectosigmoidealis anastomosissal. A resecatum sz\u00f6vettani vizsg\u00e1lata AA-amyloidosist \u00e1llap\u00edtott meg. A kivizsg\u00e1l\u00e1s sor\u00e1n a subcutan zs\u00edrsz\u00f6veti biopszia sziszt\u00e9m\u00e1s amyloidosis lehet\u0151s\u00e9g\u00e9t vetette fel. Az immunelektrofor\u00e9zis emelkedett gamma-globulin-frakci\u00f3t, ezen bel\u00fcl IgG-\u03bb-monoclonalis komponenst \u00e9s egy m\u00e1sik \u03bb-t\u00edpus\u00fa k\u00f6nny\u0171l\u00e1nckomponenst \u00e1llap\u00edtott meg. Ez\u00e9rt Jamshidi-biopszia t\u00f6rt\u00e9nt, mely myeloma multiplexet igazolt.<jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>Beteg\u00fcnkn\u00e9l a ritka, vastagbelet obstru\u00e1l\u00f3, tumort ut\u00e1nz\u00f3 b\u00e9lfali amyloidosis vezetett el a myeloma multiplex diagn\u00f3zis\u00e1hoz. A hematol\u00f3giai k\u00f3rk\u00e9p c\u00e9lzott kezel\u00e9se mellett ilyen esetben sz\u00fcks\u00e9ges lehet a k\u00f6r\u00fcl\u00edrt sz\u0171k\u00fclet endoszk\u00f3pos stentel\u00e9se vagy a seb\u00e9szi ter\u00e1pia.<\/jats:p>","DOI":"10.1556\/oh.2008.28365","type":"journal-article","created":{"date-parts":[[2008,6,11]],"date-time":"2008-06-11T18:54:31Z","timestamp":1213210471000},"page":"1181-1185","source":"Crossref","is-referenced-by-count":2,"title":["Amyloidosis induced colonic stricture. The first symptom of myeloma multiplex. A case report"],"prefix":"10.1556","volume":"149","author":[{"given":"Anita","family":"Annah\u00e1zi","sequence":"first","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar I. 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