{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:05:34Z","timestamp":1789679134572,"version":"4.0.1"},"reference-count":50,"publisher":"Akademiai Kiado Zrt.","issue":"46","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,11,1]]},"abstract":"<jats:p>A melanoma malignumban szenved\u0151 betegek sz\u00e1ma \u00e9vr\u0151l \u00e9vre emelkedik a vil\u00e1g sz\u00e1mos orsz\u00e1g\u00e1ban, k\u00f6zt\u00fck haz\u00e1nkban is. A betegs\u00e9g kialakul\u00e1s\u00e1ban szerepet j\u00e1tsz\u00f3 konstitucion\u00e1lis \u00e9s k\u00f6rnyezeti t\u00e9nyez\u0151k felismer\u00e9se, ez\u00e1ltal a fokozott rizik\u00f3nak kitett szem\u00e9lyek azonos\u00edt\u00e1sa a primer prevenci\u00f3 elengedhetetlen eszk\u00f6zei. \n <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n Jelen vizsg\u00e1latunkban felm\u00e9rt\u00fck a k\u00fcl\u00f6nb\u00f6z\u0151 fest\u00e9ksejtes b\u0151relv\u00e1ltoz\u00e1sok el\u0151fordul\u00e1s\u00e1nak gyakoris\u00e1g\u00e1t serd\u00fcl\u0151 \u00e9s fiatal feln\u0151tt koroszt\u00e1ly k\u00f6r\u00e9ben. \n <jats:italic>M\u00f3dszerek:<\/jats:italic>\n Felm\u00e9r\u00e9s\u00fcnkben 1320, 14 \u00e9s 18 \u00e9v k\u00f6z\u00f6tti k\u00f6z\u00e9piskolai tanul\u00f3 vett r\u00e9szt. A b\u0151rgy\u00f3gy\u00e1szati sz\u0171r\u0151vizsg\u00e1lat sor\u00e1n a k\u00f6z\u00f6ns\u00e9ges fest\u00e9ksejtes anyajegy, az at\u00edpusos anyajegy, a velesz\u00fcletett anyajegy, a lentigo \u00e9s a szepl\u0151 prevalenci\u00e1j\u00e1t hat\u00e1roztuk meg. A di\u00e1kok k\u00f6r\u00e9ben sz\u00e9tosztott k\u00e9rd\u0151\u00edv seg\u00edts\u00e9g\u00e9vel arra kerest\u00fck a v\u00e1laszt, hogy a pigment\u00e1lt b\u0151relv\u00e1ltoz\u00e1sok, illetve az egyes fenot\u00edpusos jellegek, napoz\u00e1si szok\u00e1sok, valamint a rosszindulat\u00fa fest\u00e9ksejtes daganatok, a nagysz\u00e1m\u00fa anyajegy csal\u00e1dban t\u00f6rt\u00e9n\u0151 esetleges el\u0151fordul\u00e1sa k\u00f6z\u00f6tt milyen \u00f6sszef\u00fcgg\u00e9s \u00e1ll fenn. \n <jats:italic>Eredm\u00e9nyek:<\/jats:italic>\n A di\u00e1kok t\u00falnyom\u00f3 t\u00f6bbs\u00e9ge rendelkezett k\u00f6z\u00f6ns\u00e9ges fest\u00e9ksejtes anyajeggyel: 1\u201310 sz\u00e1m\u00fa anyajegy 27%-n\u00e1l, 10\u2013100 sz\u00e1m\u00fa anyajegy 67%-n\u00e1l, m\u00edg nagysz\u00e1m\u00fa, 100 feletti anyajegy 5,4%-n\u00e1l fordult el\u0151. A vizsg\u00e1latban r\u00e9szt vett egy\u00e9nek 24,3%-\u00e1n\u00e1l fordult el\u0151 klinikailag at\u00edpusos anyajegy, a velesz\u00fcletett anyajegyek gyakoris\u00e1ga 6,2% volt. A vizsg\u00e1lt faktorok k\u00f6z\u00fcl a nem, a hajsz\u00edn, a szemsz\u00edn, a b\u0151rt\u00edpus, a gyermekkori h\u00f3lyagos nap\u00e9g\u00e9s el\u0151fordul\u00e1sa, valamint a csal\u00e1dban el\u0151fordul\u00f3 nagysz\u00e1m\u00fa fest\u00e9ksejtes anyajegy statisztikailag szignifik\u00e1ns kapcsolatot mutatott az egyes pigment\u00e1lt b\u0151relv\u00e1ltoz\u00e1sok el\u0151fordul\u00e1s\u00e1nak gyakoris\u00e1g\u00e1val. \n <jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic>\n A vil\u00e1girodalmi adatokhoz k\u00e9pest igen magas volt az at\u00edpusos anyajeggyel, illetve a nagysz\u00e1m\u00fa k\u00f6z\u00f6ns\u00e9ges anyajeggyel rendelkez\u0151 fiatalok sz\u00e1ma, ami m\u00e1r \u00f6nmag\u00e1ban is egy\u00e9rtelm\u0171en jelzi a b\u0151r rosszindulat\u00fa fest\u00e9ksejtes daganat\u00e1nak kialakul\u00e1s\u00e1ra val\u00f3 fokozott hajlamot az adott popul\u00e1ci\u00f3n bel\u00fcl. Eredm\u00e9nyeink igazolj\u00e1k, hogy a melanoma megel\u0151z\u00e9s\u00e9t szolg\u00e1l\u00f3 felvil\u00e1gos\u00edt\u00f3 programokkal m\u00e1r a fiatal koroszt\u00e1lyokat \u00e9rdemes megc\u00e9lozni. Rendszeres eg\u00e9szs\u00e9gnevel\u0151 tev\u00e9kenys\u00e9ggel \u00e9s megfelel\u0151 sz\u0171r\u0151vizsg\u00e1latokkal, a magas kock\u00e1zat\u00fa szem\u00e9lyek kiemel\u00e9s\u00e9n \u00e9s gondoz\u00e1s\u00e1n kereszt\u00fcl a melanoma mortalit\u00e1si ar\u00e1ny\u00e1nak jelent\u0151s cs\u00f6kken\u00e9s\u00e9t \u00e9rhetj\u00fck el.<\/jats:p>","DOI":"10.1556\/oh.2008.28446","type":"journal-article","created":{"date-parts":[[2008,11,13]],"date-time":"2008-11-13T22:53:07Z","timestamp":1226616787000},"page":"2173-2182","source":"Crossref","is-referenced-by-count":4,"title":["The prevalence of melanocytic naevi among teenagers"],"prefix":"10.1556","volume":"149","author":[{"given":"Zsanett","family":"Csoma","sequence":"first","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Erdei","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00f3ra","family":"Bartusek","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9va","family":"D\u00f3sa-R\u00e1cz","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"Dobozy","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lajos","family":"Kem\u00e9ny","sequence":"additional","affiliation":[{"name":"2 A Magyar Tudom\u00e1nyos Akad\u00e9mia \u00e9s a Szegedi Tudom\u00e1nyegyetem Dermatol\u00f3giai Kutat\u00f3csoportja Szeged"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Ol\u00e1h","sequence":"additional","affiliation":[{"name":"1 Szegedi Tudom\u00e1nyegyetem B\u0151rgy\u00f3gy\u00e1szati \u00e9s Allergol\u00f3giai Klinika Szeged Kor\u00e1nyi fasor 6. 6720"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1016\/j.ejca.2004.06.003","volume":"40","year":"2004","journal-title":"Eur. 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