{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:10:09Z","timestamp":1649031009449},"reference-count":22,"publisher":"Akademiai Kiado Zrt.","issue":"40","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,10,1]]},"abstract":"<jats:p>A szerz\u0151 \u00f6sszefoglalja a benignus prostata-hyperplasi\u00e1ban jelenleg alkalmazott gy\u00f3gyszereket. A n\u00f6v\u00e9nyi kivonatokkal szerzett tapasztalatok k\u00e9t \u00e9vtizedes m\u00faltra tekintenek vissza, alkalmaz\u00e1suk a benignus prostata-hyperplasia inici\u00e1lis f\u00e1zis\u00e1ban javasolt. A hormon\u00e1lis hat\u00e1s\u00fa 5-alfa-redukt\u00e1z finasterid jelent\u0151s, b\u00e1r csak t\u00f6bb \u00e9v-h\u00f3nap alatt kialakul\u00f3 prostatavolumen-redukci\u00f3 a vizel\u00e9si zavarok mechanikus komponens\u00e9t befoly\u00e1solja kedvez\u0151en. Indik\u00e1ci\u00f3ja f\u0151leg a 40 g feletti prostatavolumen eset\u00e9n \u00e1ll fenn. Az alfa-receptor-g\u00e1tl\u00f3k a h\u00f3lyagnyakra hat\u00f3, r\u00f6vid ter\u00e1pi\u00e1s idej\u0171 relax\u00e1ns hat\u00e1sokkal a prostata-hyperplasia dinamikus komponens\u00e9re hatnak, alkalmaz\u00e1suk indokolt minden benignus prostata-hyperplasia eset\u00e9ben, f\u00fcggetlen\u00fcl a prostatavolument\u0151l. T\u00f6bb-kevesebb hypotoni\u00e1s mell\u00e9khat\u00e1ssal sz\u00e1molni kell. Az ut\u00f3bbi id\u0151ben az 5-foszfodi\u00e9szter\u00e1z-g\u00e1tl\u00f3k kedvez\u0151 hat\u00e1s\u00e1t is le\u00edrt\u00e1k, illetve az is nyilv\u00e1nval\u00f3v\u00e1 v\u00e1lt, hogy az alfa-blokkol\u00f3kkal kezelt beteg szexu\u00e1lis aktivit\u00e1sa is fokoz\u00f3dik.<\/jats:p>","DOI":"10.1556\/oh.2008.28462","type":"journal-article","created":{"date-parts":[[2008,9,25]],"date-time":"2008-09-25T01:08:32Z","timestamp":1222304912000},"page":"1875-1880","source":"Crossref","is-referenced-by-count":0,"title":["Conservative treatment of benign prostatic hyperplasia"],"prefix":"10.1556","volume":"149","author":[{"given":"Imre","family":"Romics","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Urol\u00f3giai Klinika Budapest \u00dcll\u0151i \u00fat 78\/b 1082"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/S0140-6736(95)91085-9","volume":"345","year":"1995","journal-title":"Lancet"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/(SICI)1097-0045(199610)29:4<231::AID-PROS4>3.0.CO;2-E","volume":"29","year":"1996","journal-title":"Prostate"},{"key":"atypb3","first-page":"381","volume":"165","year":"2001","journal-title":"J. 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