{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T10:13:13Z","timestamp":1648548793409},"reference-count":48,"publisher":"Akademiai Kiado Zrt.","issue":"51","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,12,1]]},"abstract":"<jats:p>A szerz\u0151 a magzatok csontjainak \u00e9s \u00edz\u00fcleteinek funkci\u00f3j\u00e1t, majd patol\u00f3gi\u00e1j\u00e1t t\u00e1rgyalja. A csontok biztos\u00edtj\u00e1k a test statik\u00e1j\u00e1t, a koponya \u00e9s a gerincoszlop v\u00e9di a k\u00f6zponti idegrendszert, a mellkas a sz\u00edvet \u00e9s a t\u00fcd\u0151t, a medence pedig a hasi szerveket. Mindezek k\u00f3ros elv\u00e1ltoz\u00e1sai vesz\u00e9lyeztetik a szervek norm\u00e1lis m\u0171k\u00f6d\u00e9s\u00e9t. A csontok mozg\u00e1s\u00e1t az \u00edz\u00fcletek \u00e9s az izmok teszik lehet\u0151v\u00e9. A v\u00e9gtagok abnormalit\u00e1sai a mozg\u00e1sokat korl\u00e1tozz\u00e1k (\u201efoetal akinesia deformation sequence\u201d). Akinesi\u00e1t id\u00e9zhetnek el\u0151 els\u0151sorban a csont-, az \u00edz\u00fcleti, tov\u00e1bb\u00e1 idegrendszeri, izom-, esetleg b\u0151rbetegs\u00e9gek, amelyek befoly\u00e1solj\u00e1k a csontok \u00e9s \u00edz\u00fcletek \u00e1llapot\u00e1t, funkci\u00f3k\u00e9pess\u00e9g\u00e9t. Mindezek a k\u00f3ros elv\u00e1ltoz\u00e1sok aktivit\u00e1skorl\u00e1toz\u00e1st vagy rokkants\u00e1got okoznak, s\u00falyos esetben hal\u00e1losak. Ultrahanggal a betegs\u00e9gek kor\u00e1n kimutathat\u00f3k, \u00e9s rem\u00e9nytelen esetben a terhess\u00e9g megszak\u00edt\u00e1sa javasolt.<\/jats:p>","DOI":"10.1556\/oh.2008.28499","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T03:33:58Z","timestamp":1228966438000},"page":"2425-2431","source":"Crossref","is-referenced-by-count":0,"title":["Fetal bone and joint disorders"],"prefix":"10.1556","volume":"149","author":[{"given":"\u00c1kos","family":"Jakobovits","sequence":"first","affiliation":[{"name":"1 Toldy Ferenc K\u00f3rh\u00e1z Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Oszt\u00e1ly Cegl\u00e9d Pf. 63. 2700"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s00247-001-0644-9","volume":"32","year":"2002","journal-title":"Pediatr. Radio."},{"key":"atypb2","volume-title":"Developmental neuropathology. 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