{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T13:50:13Z","timestamp":1749822613463},"reference-count":37,"publisher":"Akademiai Kiado Zrt.","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,4,1]]},"abstract":"<jats:p>Most 25 \u00e9ve, 1984-ben \u00e9szlelt\u00fck az els\u0151 hazai Lyme-betegeket, \u00e9s pontosan 20 \u00e9ve, hogy a L\u00e1szl\u00f3 K\u00f3rh\u00e1zban megnyitottuk a Lyme-ambulanci\u00e1t, \u00e9s \u00e9ppen 15 \u00e9ve, hogy mag\u00e1npraxis keret\u00e9ben megnyitottuk a Kullancsbetegs\u00e9gek Ambulanci\u00e1j\u00e1t. Az itt v\u00e9gzett munka legfontosabb \u00e1llom\u00e1sai: egy \u00faj, kullancs \u00e1ltal terjesztett Rickettsia-fert\u0151z\u00e9s (tick-borne lymphadenopathy) le\u00edr\u00e1sa, egy Lyme-immunoblotkit \u00e9s a hozz\u00e1 kapcsol\u00f3d\u00f3 automata immunoblot reader kifejleszt\u00e9se. Le\u00edrtunk egy \u00faj \u00e9s a kor\u00e1bbiakn\u00e1l egyszer\u0171bb, megb\u00edzhat\u00f3bb m\u00f3dszert az intrathecalis borrelia antitest meghat\u00e1roz\u00e1s\u00e1ra, ami n\u00e9lk\u00fcl\u00f6zhetetlen a neuroborreliosis al\u00e1t\u00e1maszt\u00e1s\u00e1ra. Rutinszer\u0171en alkalmazzuk az \u00e1ltalunk kifejlesztett \u00f6sszehasonl\u00edt\u00f3 immunoblot-vizsg\u00e1latot (comparative immunoblot assay), ami alkalmas annak a kider\u00edt\u00e9s\u00e9re, hogy a szeropozit\u00edv lelet h\u00e1tter\u00e9ben egy jelenleg is fenn\u00e1ll\u00f3 vagy \u00e9pp r\u00e9gen lezajlott \u00e9s gy\u00f3gyult fert\u0151z\u00e9sr\u0151l van-e sz\u00f3. Terhess\u00e9gi Lyme-fert\u0151z\u00e9seket vizsg\u00e1lva els\u0151k\u00e9nt bizony\u00edtottuk be, hogy a kezeletlen\u00fcl maradtak eset\u00e9ben gyakoribbak a magzati k\u00e1rosod\u00e1sok.<\/jats:p>","DOI":"10.1556\/oh.2009.28576","type":"journal-article","created":{"date-parts":[[2009,4,12]],"date-time":"2009-04-12T01:01:50Z","timestamp":1239498110000},"page":"725-732","source":"Crossref","is-referenced-by-count":3,"title":["Lyme borreliosis \u2013 lessons learnt from 25 years"],"prefix":"10.1556","volume":"150","author":[{"given":"Andr\u00e1s","family":"Lakos","sequence":"first","affiliation":[{"name":"1 Kullancsbetegs\u00e9gek Ambulanci\u00e1ja Budapest Visegr\u00e1di u. 14. 1132"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"atypb3","first-page":"741","volume":"108","year":"1996","journal-title":"Wien. Klin. Wochenschr."},{"key":"atypb4","first-page":"21","volume":"4","year":"1999","journal-title":"H\u00e1ziorvos Tov\u00e1bbk\u00e9pz\u0151 Szle"},{"key":"atypb5","volume-title":"Klinikai \u00e9s j\u00e1rv\u00e1ny\u00fcgyi bakteriol\u00f3gia","year":"1999"},{"key":"atypb6","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1111\/j.1469-0691.2004.01019.x","volume":"10","year":"2004","journal-title":"Clin. Microbiol. Infect."},{"key":"atypb7","volume-title":"Infektol\u00f3giai \u00fatmutat\u00f3. (Klinikai ir\u00e1nyelvek k\u00e9zik\u00f6nyve.)","year":"2004"},{"key":"atypb8","first-page":"5","volume":"13","year":"2008","journal-title":"H\u00e1ziorvosi Tov\u00e1bbk\u00e9pz\u0151 Szle"},{"key":"atypb9","first-page":"5","volume":"29","year":"1996","journal-title":"Parasit. Hung."},{"key":"atypb10","first-page":"129","volume":"132","year":"1991","journal-title":"Orv. Hetil."},{"key":"atypb14","volume-title":"A Lyme borreliosis. Klinikai t\u00fcnetek, ter\u00e1pia, epidemiol\u00f3gia, szerodiagnosztika","year":"1991"},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.3201\/eid1111.050542","volume":"11","year":"2005","journal-title":"Emerg. Inf. Dis."},{"key":"atypb16","first-page":"2697","volume":"126","year":"1985","journal-title":"Orv. Hetil."},{"key":"atypb17","volume-title":"Kullancsok \u00e9s betegs\u00e9gek","year":"1992"},{"key":"atypb18","first-page":"1983","volume":"128","year":"1987","journal-title":"Orv. Hetil."},{"key":"atypb19","first-page":"80","volume":"1","year":"1999","journal-title":"Gyermekgy\u00f3gy\u00e1szati Figyel\u0151"},{"key":"atypb20","first-page":"2143","volume":"129","year":"1988","journal-title":"Orv. Hetil."},{"key":"atypb21","first-page":"2311","volume":"130","year":"1989","journal-title":"Orv. Hetil."},{"key":"atypb22","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1111\/j.1540-8159.1989.tb05059.x","volume":"12","year":"1989","journal-title":"Pacing Clin. Electrophysiol."},{"key":"atypb23","first-page":"73","volume":"41","year":"1988","journal-title":"Ideggy. Szle"},{"key":"atypb24","first-page":"1257","volume":"129","year":"1988","journal-title":"Orv. Hetil."},{"key":"atypb25","first-page":"654","volume":"24","year":"1988","journal-title":"Pediatr. Res."},{"key":"atypb26","volume-title":"Betegs\u00e9genciklop\u00e9dia","year":"2002"},{"key":"atypb27","first-page":"1","volume":"25","year":"1992","journal-title":"J. Infection"},{"key":"atypb29","first-page":"1439","volume":"127","year":"1986","journal-title":"Orv. Hetil."},{"key":"atypb30","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1093\/intimm\/dxh343","volume":"17","year":"2005","journal-title":"Int. Immunol."},{"key":"atypb33","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0888-0786(90)90014-F","volume":"4","year":"1990","journal-title":"Serod. Immunother."},{"key":"atypb34","first-page":"101","volume":"4","year":"1997","journal-title":"Infektol\u00f3gia \u00e9s Klinikai Mikrobiol\u00f3gia"},{"key":"atypb36","first-page":"26","volume":"5","year":"1998","journal-title":"Infektol\u00f3gia \u00e9s Klinikai Mikrobiol\u00f3gia"},{"key":"atypb37","first-page":"20","volume":"16","year":"2008","journal-title":"Medicus Anonymus"},{"key":"atypb38","volume-title":"Klinikai \u00e9s j\u00e1rv\u00e1ny\u00fcgyi bakteriol\u00f3gia","year":"1999"},{"key":"atypb39","first-page":"11","volume":"10","year":"2002","journal-title":"Medicus Anonymus"},{"key":"atypb40","volume-title":"Reumatol\u00f3gia","year":"2001"},{"key":"atypb41","first-page":"3229","volume":"138","year":"1997","journal-title":"Orv. Hetil."},{"key":"atypb42","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0140-6736(05)64072-X","volume":"350","year":"1997","journal-title":"Lancet"},{"key":"atypb43","first-page":"648","volume":"114","year":"2002","journal-title":"Wien. Klin. Wochenshr."},{"key":"atypb44","first-page":"88","volume":"49","year":"1999","journal-title":"Gy\u00f3gyszereink"},{"key":"atypb45","first-page":"613","volume":"5","year":"1993","journal-title":"J.\u00a0Chemother."},{"key":"atypb46","first-page":"1529","volume":"140","year":"1999","journal-title":"Orv. Hetil."}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/150\/16\/article-p725.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/150\/16\/article-p725.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T10:19:30Z","timestamp":1590574770000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/150\/16\/article-p725.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,1]]},"references-count":37,"journal-issue":{"issue":"16"},"URL":"https:\/\/doi.org\/10.1556\/oh.2009.28576","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,1]]}}}